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Central nervous system drugs

Trimipramine

Also known as Trimeprimine, Trimeproprimine, Sapilent

CAS 739-71-9Formula C20H26N2Molar mass 294.44 g/molEC 212-008-3
GHS signal word: Danger. Pictograms: Corrosive, Acute toxicity (severe), Harmful or irritant, Hazardous to the environment 32 suppliers listed Drug substance
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Trimipramine chemical structure, C20H26N2, CAS 739-71-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
739-71-9
Formula
C20H26N2
Molar mass
294.44 g/mol
EC number
212-008-3
HS code
293399
Category
Central nervous system drugs

What is Trimipramine?

Plain description, key identifiers and synonyms

Trimipramine is a dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant. It has a role as an antidepressant, a xenobiotic and an environmental contaminant. It is a dibenzoazepine and a tertiary amino compound. It is functionally related to an imipramine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine
CAS number
739-71-9 CAS number cross-checkedOther or deprecated CAS: 3564-66-7
EC number
212-008-3
Molecular formula
C20H26N2
UNII
6S082C9NDT, 9K5931C1H5, QJ9MUH57H8
InChIKey
ZSCDBOWYZJWBIY-UHFFFAOYSA-N
InChI
InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3
SMILES (canonical and isomeric)
CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C

Synonyms

  • Trimeprimine
  • Trimeproprimine
  • Sapilent
  • beta-Methylimipramine
  • Trimeprimina
  • Trimipramina
  • Trimipraminum
  • 7162 RP
  • IL 6001
  • 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine
  • 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine
  • 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine
  • 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine
  • 5-(gamma-Dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine
  • 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-
  • 5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
  • 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine
  • 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)-2-methylpropyl)-10,11-dihydro-
  • 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-
  • NovoTripramine
  • NuTrimipramine
  • ApoTrimip
  • Novo Tripramine
  • Nu Trimipramine
  • Apo Trimip
Show all 35 synonyms
  • 3-(5,6-dihydrobenzo(b)(1)benzazepin-11-yl)-N,N,2-trimethylpropan-1-amine
  • 10,11-Dihydro-N,n,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine
  • Beta, Trimipramin
  • (3-(2-azatricyclo(9.4.0.0^(3,8))pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-2-methylpropyl)dimethylamine
  • (3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}-2-methylpropyl)dimethylamine
  • Trimipraminneurazpharm
  • Trimipramin neurazpharm
  • (3-(2-azatricyclo(9.4.0.03,8)pentadeca-1(15),3,5,7,11,13-hexaen-2-yl)-2-methylpropyl)dimethylamine
  • Surmontil
  • (+)-Trimipramine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
294.44 g/molcalc.
Exact mass
294.2096 Dacalc.
LogP (octanol/water)
4.12calc.
Topological polar surface area
6.48 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
4calc.
Heavy atoms
22calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)CCc1ccccc1N2

c1ccc2c(c1)CCc1ccccc1N2

3 rings, 15 atoms, the Iminodibenyl ring system.

268 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H301Toxic if swallowed.
  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H336May cause drowsiness or dizziness.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (23)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Trimipramine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 32 suppliers
30 of 30 offers
  • Medkem
    India, Hyderabad ManufacturerUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • Faes Farma, SA
    Spain, Leioa ManufacturerUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • Rivopharm SA
    Switzerland, Manno ManufacturerUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • 10X Chem
    United States, San DiegoUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • 3WAY Pharm Inc
    China, ShanghaiUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • A2B Chem LLC
    United States, San DiegoUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • Aa Blocks LLC
    United States, San DiegoUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • AbaChemScene, LLC
    United States, Monmouth JunctionUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
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  • AKos Consulting & Solutions
    Germany, LorrachUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
    View
  • Amadis Chemical Co., Ltd.
    China, HangzhouUnclaimed profile
    TrimipramineGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

32 suppliers in 11 countries

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Trimipramine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals, Nervous System.

Industries and functions

Pharmacological actions

  • Adrenergic Uptake Inhibitors
  • Antidepressive Agents, Tricyclic

Roles

  • antidepressant
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • environmental contaminant
  • pharmaceutical
  • psychotropic drug
  • tranquilizing drug
  • xenobiotic

Pharmacology

Trimipramine is a Tricyclic Antidepressant.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Trimipramine is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Trimipramine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Trimipramine, based on the data on this page

What is Trimipramine?

Trimipramine is a dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant. It has a role as an antidepressant, a xenobiotic and an environmental contaminant.

What is the CAS number of Trimipramine?

The CAS registry number of Trimipramine is 739-71-9. Other or deprecated CAS numbers: 3564-66-7.

What is the molecular formula and weight of Trimipramine?

The molecular formula of Trimipramine is C20H26N2 and its molar mass is 294.44 g/mol.

What is Trimipramine used for?

Use classes: Pharmaceuticals, Nervous System.

Is Trimipramine hazardous?

Trimipramine carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes skin irritation, may cause an allergic skin reaction. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Trimipramine?

Trimipramine is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Trimipramine?

CompoundList lists 32 suppliers of Trimipramine in United States, China, Germany, Switzerland and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Trimipramine in India?

1 supplier in India list Trimipramine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Trimipramine?

Suppliers quote Trimipramine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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