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Virginiamycin chemical structure, C71H84N10O17, CAS 11006-76-1
2D chemical structure

Key facts

What buyers check first

Appearance
Reddish-yellow powder
Melting point
115 to 120
Solubility
Poorly soluble in water
HS code
294190
Category
Antibiotics and anti-infectives
Illustrative photo, yellow pigment powder in an open kraft paper sack in a chemical plant
Typical packagingIllustrative packaging image, not the actual product

What is Virginiamycin?

Plain description, key identifiers and synonyms

Virginiamycin is a class of streptogramin-related depsipeptides isolated from the bacterium Streptomyces virginiae and other Streptomyces bacterial species. The virginiamycins consist of two major components, virginiamycin M1 and virginiamycin S1. These agents bind to and inhibit ribosome assembly, thereby preventing protein synthesis. Active against Gram-positive bacteria, these antibiotics are primarily used in veterinary practice. (NCI04)

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[(3S,6S,12R,15S,16R,19S,22S)-3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide, (10R,11R,12E,17E,19E,21S)-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),6,12,17,19,25(28)-hexaene-2,8,14,23-tetrone
CAS number
11006-76-1 CAS number cross-checked
EC number
234-244-6
Molecular formula
C71H84N10O17
UNII
C49WS9N75L
InChIKey
MVTQIFVKRXBCHS-SMMNFGSLSA-N
InChI
InChI=1S/C43H49N7O10.C28H35N3O7/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36;1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53);5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b;7-5+,10-9+,18-13+/t25-,29-,30+,31+,32+,34+,35+;19-,20-,26-/m11/s1
Canonical SMILES
CC1=CC(O)CC(=O)Cc2nc(co2)C(=O)N2CCC=C2C(=O)OC(C(C)C)C(C)C=CC(=O)NCC=C1.CCC1NC(=O)C(NC(=O)c2ncccc2O)C(C)OC(=O)C(c2ccccc2)NC(=O)C2CC(=O)CCN2C(=O)C(Cc2ccccc2)N(C)C(=O)C2CCCN2C1=O
Isomeric SMILES
CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C.C[C@@H]1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C)C)O)/C

Synonyms

  • Staphylomycin
  • Stapyocine
  • Virgimycin
  • Virginiamicina
  • Virginiamycina
  • Virginiamycine
  • Virginiamycinum
  • Eskalin
  • Patricin
  • Stafac 20
  • Stafac 50
  • Eskalin 500
  • Stafac 500
  • Antibiotic No. 899
  • Streptogramin
  • Stafac
  • V-MAX 50
  • Eskalin V
  • SKF 7988
  • SK&F 7988
  • Virgimycine
  • Lactrol
  • Livelong
  • Eskalin (Vet)
  • Staphylomycine
Show all 38 synonyms
  • V-MAX
  • V-Max, V-Max 50
  • SK&F-7988
  • Stafac 500, Stafac 10, Stafac 20, Stafac 50
  • Micamicina
  • Mikamycine
  • Mikamycinum
  • Ostreogricina
  • Ostreogrycine
  • Ostreogrycinum
  • Pristinamicina
  • Pristinamycinum
  • RP 7293

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Reddish-yellow powderexp.
Melting point
115 to 120exp.
Solubility
Poorly soluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,349.51 g/molcalc.
Exact mass
1,348.6016 Dacalc.
LogP (octanol/water)
3.86calc.
Topological polar surface area
363.8 Ųcalc.
Hydrogen bond donors
6calc.
Hydrogen bond acceptors
19calc.
Rotatable bonds
7calc.
Heavy atoms
98calc.
Rings
9calc.
Aromatic rings
4calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
10calc.
Components
2calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCN2C(=O)C(Cc3ccccc3)NC(=O)C3CCCN3C(=O)CNC(=O)C(NC(=O)c3ccccn3)COC(=O)C(c3ccccc3)NC(=O)C2C1

O=C1CCN2C(=O)C(Cc3ccccc3)NC(=O)C3CCCN3C(=O)CNC(=O)C(NC(=O)c3ccccn3)COC(=O)C(c3ccccc3)NC(=O)C2C1

6 rings, 55 atoms.

10 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS05: Corrosive
Corrosive
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H302Harmful if swallowed.
  • H317May cause an allergic skin reaction.
  • H318Causes serious eye damage.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (17)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Virginiamycin suppliers

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Virginiamycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

FDA approved nutritional feed additive for chicken, turkey, and swine for food efficiency/growth promotion.

Veterinary medication:.

Use classes: Animal Drugs.

Pharmacological actions

  • Anti-Bacterial Agents
  • Protein Synthesis Inhibitors

Roles

  • antibacterial agent
  • antibacterial drug
  • antiinfective agent
  • antimicrobial agent
  • antimicrobial drug
  • bacterial metabolite
  • metabolite
  • pharmaceutical
  • prokaryotic metabolite

How it is made

Virginiamycin is an antibiotic complex produced by a Streptomyces related to S. virginiae. It is a mixture of two principal components designated virginiamycin M1 (21411-53-0) and virginiamycin S1 (23152-29-6).

Antibiotics are fermentation products and are isolated either as unfinished products or as intermediates, generally solid substances of limited stability. They are purified by methods normally employed in organic chemistry, which include chromatography, crystallization, and precipitation. (Antibiotics)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Virginiamycin is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Virginiamycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Virginiamycin, based on the data on this page

What is Virginiamycin?

Virginiamycin is a class of streptogramin-related depsipeptides isolated from the bacterium Streptomyces virginiae and other Streptomyces bacterial species. The virginiamycins consist of two major components, virginiamycin M1 and virginiamycin S1.

What is the CAS number of Virginiamycin?

The CAS registry number of Virginiamycin is 11006-76-1.

What is the molecular formula and weight of Virginiamycin?

The molecular formula of Virginiamycin is C71H84N10O17 and its molar mass is 1,349.51 g/mol.

What is Virginiamycin used for?

FDA approved nutritional feed additive for chicken, turkey, and swine for food efficiency/growth promotion. Veterinary medication:. Use classes: Animal Drugs.

Is Virginiamycin hazardous?

Virginiamycin carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause an allergic skin reaction, causes serious eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Virginiamycin?

Virginiamycin is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Virginiamycin?

CompoundList lists 11 suppliers of Virginiamycin in Germany, India, China, Israel and 2 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Virginiamycin in India?

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What is the price of Virginiamycin?

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Guides for buyers

Practical guides that help when you source, ship or handle Virginiamycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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