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Rodenticides, nematicides and other pesticides

Warfarin

Also known as Coumafene, Zoocoumarin, Coumafen

CAS 81-81-2Formula C19H16O4Molar mass 308.33 g/molEC 201-377-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard, Hazardous to the environment 93 suppliers listed Drug substance
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Warfarin chemical structure, C19H16O4, CAS 81-81-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from alcohol
Melting point
161 °C
Boiling point
356 °C
Density
Relative density (water = 1): 1.4
Solubility
1 g in 1.5 mL water, 1.9 mL alcohol, >10,000 mL chloroform, >10,000 mL ether /Warfarin p…
HS code
293220
Category
Rodenticides, nematicides and other pesticides
UN number
UN 3027
Illustrative photo, drums, an IBC tote and sacks in a chemical warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Warfarin?

Plain description, key identifiers and synonyms

4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one is a member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. It is a member of benzenes, a hydroxycoumarin and a methyl ketone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one
CAS number
81-81-2 CAS number cross-checkedOther or deprecated CAS: 951658-59-6
EC number
201-377-6
Molecular formula
C19H16O4
UNII
5Q7ZVV76EI
MDL number
MFCD00006854
InChIKey
PJVWKTKQMONHTI-UHFFFAOYSA-N
InChI
InChI=1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3
SMILES (canonical and isomeric)
CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O

Synonyms

  • Coumafene
  • Zoocoumarin
  • Coumafen
  • Brumolin
  • Coumefene
  • Dethmor
  • Kumader
  • Warfarine
  • Kumadu
  • Vampirinip II
  • Coumarins
  • Kypfarin
  • Rodafarin
  • Solfarin
  • Dethnel
  • Kumatox
  • Maveran
  • Ratron
  • Rosex
  • Temus W
  • Vampirinip iii
  • Athrombine-K
  • Frass-Ratron
  • Mar-Frin
  • Rattentraenke
Show all 39 synonyms
  • Ratorex
  • Rattunal
  • Warfarat
  • CO-Rax
  • Rats-no-more
  • Tox-hid
  • Rat-Gard
  • Rat-Kill
  • Rat-Trol
  • Ratron G
  • Ratten-Koederrohr
  • Coumaphene
  • Rat-Mix
  • Rat-Ola

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from alcoholexp.
Odour
Odorlessexp.
Taste
Tastelessexp.
Melting point
161 °Cexp.
Boiling point
356 °Cexp.
Density
Relative density (water = 1): 1.4exp.
Solubility
1 g in 1.5 mL water, 1.9 mL alcohol, >10,000 mL chloroform, >10,000 mL ether /Warfarin potassium/exp.
Vapour pressure
1.5 × 10⁻³ mPa /1.125 × 10⁻⁸ mm Hg/ at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
308.33 g/molcalc.
Exact mass
308.1049 Dacalc.
LogP (octanol/water)
3.61calc.
Topological polar surface area
67.51 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
23calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.16calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1oc2ccccc2cc1Cc1ccccc1

O=c1oc2ccccc2cc1Cc1ccccc1

3 rings, 18 atoms, the 3-Benzyl-2H-1-benzopyran-2-one ring system.

221 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
  • H360DMay damage the unborn child.
  • H372Causes damage to organs through prolonged or repeated exposure.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (23)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 3027
Transport hazard class
6.1
Packing group
I

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Warfarin suppliers

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All 93 suppliers
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Where suppliers are based

93 suppliers in 13 countries

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Warfarin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Warfarin and its sodium salt are registered for use in controlling commensal rodents (rats and mice) in and around homes, animal and agricultural premises, and commercial and industrial sites.

Warfarin is a blood anticoagulant, its sodium salt is used medically to treat people with blood hypercoagulation problems.

Warfarin has been used successfully against common vampire bats.

Use classes: Rodenticides.

Pharmacological actions

  • Anticoagulants
  • Rodenticides

Roles

  • anti-arrhythmia drug
  • anti-inflammatory agent
  • anti-obesity agent
  • antiatherosclerotic agent
  • anticoagulant
  • anticonvulsant
  • antidepressant
  • antiemetic
  • antifibrotic agent
  • antihypertensive agent
  • antineoplastic agent
  • antiparkinson drug
  • antipsoriatic
  • antirheumatic drug
  • cardiovascular drug
  • dermatologic drug
  • hepatoprotective agent
  • hypoglycemic agent
  • immunomodulator
  • immunosuppressive agent
  • pesticide
  • pharmaceutical
  • rodenticide
  • vitamin K antagonist

Pharmacology

Warfarin is a Vitamin K Antagonist. The mechanism of action of warfarin is as a Vitamin K Inhibitor.

How it is made

By addition of 4-hydroxycoumarin to benzalacetone under the catalytic influence of a mildly basic substance such as ammonia or piperidine. The reaction is a typical Michael condensation. Conversion to the sodium salt is effected by reacting purified warfarin with an equimolar portion of dilute NaOH solution at room temperature.

Prepared by the Michael condensation of benzylidene acetone with 4-hydroxycourmarin.

Preparation: M. A. Stahmann et al., United States of America patent 2427578 (1947 to Wisconsin Alumni Research Foundation)

Regulatory status

Inventories, regulations and trade controls that list this substance

Europe

  • EU harmonised classification (CLP Annex VI)
    Index no: 607-056-00-0[1]

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Warfarin (INN) and its salts, Ref no: 203, Annex ref: II/203
  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Warfarin is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Warfarin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Warfarin, based on the data on this page

What is Warfarin?

4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one is a member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. It is a member of benzenes, a hydroxycoumarin and a methyl ketone.

What is the CAS number of Warfarin?

The CAS registry number of Warfarin is 81-81-2. Other or deprecated CAS numbers: 951658-59-6.

What is the molecular formula and weight of Warfarin?

The molecular formula of Warfarin is C19H16O4 and its molar mass is 308.33 g/mol.

What is Warfarin used for?

Warfarin and its sodium salt are registered for use in controlling commensal rodents (rats and mice) in and around homes, animal and agricultural premises, and commercial and industrial sites. Warfarin is a blood anticoagulant, its sodium salt is used medically to treat people with blood hypercoagulation problems.

Is Warfarin hazardous?

Warfarin carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Warfarin?

Warfarin is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Warfarin?

CompoundList lists 93 suppliers of Warfarin in United States, China, India, Canada and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Warfarin in India?

5 suppliers in India list Warfarin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Warfarin?

Suppliers quote Warfarin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Warfarin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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