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Murcko scaffold

1,3-Dioxole scaffold

30 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
30
With full pages
2
Scaffold SMILES

C1=COCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 1,3-Dioxole page
Murcko scaffold C1=COCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

2,4-Dimethyl-1,3-dioxole chemical structure, C5H8O2, CAS 14738-97-7
2,4-Dimethyl-1,3-dioxole
CAS 14738-97-7C5H8O2
1,3-Dioxole, 4,5-difluoro-2,2-bis(trifluoromethyl)- chemical structure, C5F8O2, CAS 37697-64-6
1,3-Dioxole, 4,5-difluoro-2,2-bis(trifluoromethyl)-
CAS 37697-64-6C5F8O2
1,3-Dioxole, 4-methyl- chemical structure, C4H6O2, CAS 14738-96-6
1,3-Dioxole, 4-methyl-
CAS 14738-96-6C4H6O2
1,3-Dioxole, 2,2-bis(trifluoromethyl)- chemical structure, C5H2F6O2, CAS 89444-43-9
1,3-Dioxole, 2,2-bis(trifluoromethyl)-
CAS 89444-43-9C5H2F6O2
1,3-Dioxole, 2,2,4-trifluoro-5-(trifluoromethoxy)- chemical structure, C4F6O3, CAS 161611-74-1
1,3-Dioxole, 2,2,4-trifluoro-5-(trifluoromethoxy)-
CAS 161611-74-1C4F6O3
1,3-Dioxole, 2,2-dimethyl- chemical structure, C5H8O2, CAS 22945-10-4
1,3-Dioxole, 2,2-dimethyl-
CAS 22945-10-4C5H8O2
1,3-Dioxole chemical structure, C3H4O2, CAS 288-53-9
1,3-Dioxole
CAS 288-53-9C3H4O2
1,3-Dioxole, 4-chloro-5-fluoro-2,2-bis(trifluoromethyl)- chemical structure, C5ClF7O2, CAS 89444-42-8
1,3-Dioxole, 4-chloro-5-fluoro-2,2-bis(trifluoromethyl)-
CAS 89444-42-8C5ClF7O2
2,2-Diethyl-2H-1,3-dioxole chemical structure, C7H12O2, CAS 59953-85-4
2,2-Diethyl-2H-1,3-dioxole
CAS 59953-85-4C7H12O2
2,2,4-Trimethyl-2H-1,3-dioxole chemical structure, C6H10O2, CAS 51494-95-2
2,2,4-Trimethyl-2H-1,3-dioxole
CAS 51494-95-2C6H10O2
2-Methyl-2H-1,3-dioxole chemical structure, C4H6O2, CAS 68882-31-5
2-Methyl-2H-1,3-dioxole
CAS 68882-31-5C4H6O2
4,5-Dimethyl-2H-1,3-dioxole chemical structure, C5H8O2, CAS 85976-13-2
4,5-Dimethyl-2H-1,3-dioxole
CAS 85976-13-2C5H8O2
2,2,4,5-Tetramethyl-2H-1,3-dioxole chemical structure, C7H12O2, CAS 85976-14-3
2,2,4,5-Tetramethyl-2H-1,3-dioxole
CAS 85976-14-3C7H12O2
Ethanone, 1-(2,2,5-trimethyl-1,3-dioxol-4-yl)- chemical structure, C8H12O3, CAS 96706-10-4
Ethanone, 1-(2,2,5-trimethyl-1,3-dioxol-4-yl)-
CAS 96706-10-4C8H12O3
Methyl 2-methyl-1,3-dioxole-4-carboxylate chemical structure, C6H8O4, CAS 101544-32-5
Methyl 2-methyl-1,3-dioxole-4-carboxylate
CAS 101544-32-5C6H8O4
2,2-Di(propan-2-yl)-2H-1,3-dioxole chemical structure, C9H16O2, CAS 112183-60-5
2,2-Di(propan-2-yl)-2H-1,3-dioxole
CAS 112183-60-5C9H16O2
Perfluoro-2-ethyl-2-methyl-1,3-dioxole chemical structure, C6F10O2, CAS 130760-25-7
Perfluoro-2-ethyl-2-methyl-1,3-dioxole
CAS 130760-25-7C6F10O2
4-Fluoro-2,2,5-tris(trifluoromethyl)-1,3-dioxole chemical structure, C6F10O2, CAS 130760-30-4
4-Fluoro-2,2,5-tris(trifluoromethyl)-1,3-dioxole
CAS 130760-30-4C6F10O2
Methyl 3-(5-acetyl-2,2-dimethyl-2H-1,3-dioxol-4-yl)propanoate chemical structure, C11H16O5, CAS 923590-94-7
Methyl 3-(5-acetyl-2,2-dimethyl-2H-1,3-dioxol-4-yl)propanoate
CAS 923590-94-7C11H16O5
1,3-Dioxole, 4,5-dichloro-2,2-difluoro- chemical structure, C3Cl2F2O2, CAS 89413-95-6
1,3-Dioxole, 4,5-dichloro-2,2-difluoro-
CAS 89413-95-6C3Cl2F2O2
4,5-Dichloro-2,2-bis(trifluoromethyl)-2H-1,3-dioxole chemical structure, C5Cl2F6O2, CAS 64499-77-0
4,5-Dichloro-2,2-bis(trifluoromethyl)-2H-1,3-dioxole
CAS 64499-77-0C5Cl2F6O2
1,3-Dioxole, 4-chloro-2,2-bis(trifluoromethyl)- chemical structure, C5HClF6O2, CAS 89444-44-0
1,3-Dioxole, 4-chloro-2,2-bis(trifluoromethyl)-
CAS 89444-44-0C5HClF6O2
1,3-Dioxole, 4-chloro-2,2,5-trifluoro- chemical structure, C3ClF3O2, CAS 89444-45-1
1,3-Dioxole, 4-chloro-2,2,5-trifluoro-
CAS 89444-45-1C3ClF3O2
1,3-Dioxole, 2,2,4-trifluoro- chemical structure, C3HF3O2, CAS 89414-03-9
1,3-Dioxole, 2,2,4-trifluoro-
CAS 89414-03-9C3HF3O2