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Murcko scaffold

Thiophene scaffold

22,644 chemicals on CompoundList share this ring system.

Rings: 1
Scaffold atoms: 5
Chemicals: 22,644
With full pages: 2,330

Scaffold SMILES

c1ccsc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold Open the Thiophene page

Murcko scaffold c1ccsc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 22,644 chemicals

N-2-Thiophen-2-yl-acetamide boronic acid chemical structure, C7H10BNO3S, CAS 448211-54-9

N-2-Thiophen-2-yl-acetamide boronic acid

CAS 448211-54-9C₇H₁₀BNO₃S

Thenoyltrifluoroacetone chemical structure, C8H5F3O2S, CAS 326-91-0

Thenoyltrifluoroacetone

CAS 326-91-0C₈H₅F₃O₂S

Thiophene-3-carboxylic acid chemical structure, C5H4O2S, CAS 88-13-1

Thiophene-3-carboxylic acid

CAS 88-13-1C₅H₄O₂S

2-Acetylthiophene chemical structure, C6H6OS, CAS 88-15-3

2-Acetylthiophene

CAS 88-15-3C₆H₆OS

2-Chlorothiophene chemical structure, C4H3ClS, CAS 96-43-5

2-Chlorothiophene

CAS 96-43-5C₄H₃ClS

2-Thiophenecarboxaldehyde chemical structure, C5H4OS, CAS 98-03-3

2-Thiophenecarboxaldehyde

CAS 98-03-3C₅H₄OS

Thiophene chemical structure, C4H4S, CAS 110-02-1

CAS 110-02-1C₄H₄S

2-Thiophenecarboxylic acid chemical structure, C5H4O2S, CAS 527-72-0

2-Thiophenecarboxylic acid

CAS 527-72-0C₅H₄O₂S

2-Methylthiophene chemical structure, C5H6S, CAS 554-14-3

2-Methylthiophene

CAS 554-14-3C₅H₆S

Thiophene, 2-nitro- chemical structure, C4H3NO2S, CAS 609-40-5

Thiophene, 2-nitro-

CAS 609-40-5C₄H₃NO₂S

3-Methylthiophene chemical structure, C5H6S, CAS 616-44-4

3-Methylthiophene

CAS 616-44-4C₅H₆S

2,5-Dimethylthiophene chemical structure, C6H8S, CAS 638-02-8

2,5-Dimethylthiophene

CAS 638-02-8C₆H₈S

3-Bromothiophene chemical structure, C4H3BrS, CAS 872-31-1

3-Bromothiophene

CAS 872-31-1C₄H₃BrS

2-Ethylthiophene chemical structure, C6H8S, CAS 872-55-9

2-Ethylthiophene

CAS 872-55-9C₆H₈S

2-Bromothiophene chemical structure, C4H3BrS, CAS 1003-09-4

2-Bromothiophene

CAS 1003-09-4C₄H₃BrS

1-(Thiophen-3-yl)ethanone chemical structure, C6H6OS, CAS 1468-83-3

1-(Thiophen-3-yl)ethanone

CAS 1468-83-3C₆H₆OS

2-tert-Butylthiophene chemical structure, C8H12S, CAS 1689-78-7

2-tert-Butylthiophene

CAS 1689-78-7C₈H₁₂S

2,3,4-Trimethylthiophene chemical structure, C7H10S, CAS 1795-04-6

2,3,4-Trimethylthiophene

CAS 1795-04-6C₇H₁₀S

2-Thiopheneacetic acid chemical structure, C6H6O2S, CAS 1918-77-0

2-Thiopheneacetic acid

CAS 1918-77-0C₆H₆O₂S

Ethanone, 1-(2-thienyl)-, oxime, (1Z)- chemical structure, C6H7NOS, CAS 1956-45-2

Ethanone, 1-(2-thienyl)-, oxime, (1Z)-

CAS 1956-45-2C₆H₇NOS

3,4-Dibromothiophene chemical structure, C4H2Br2S, CAS 3141-26-2

3,4-Dibromothiophene

CAS 3141-26-2C₄H₂Br₂S

2,5-Dibromothiophene chemical structure, C4H2Br2S, CAS 3141-27-3

2,5-Dibromothiophene

CAS 3141-27-3C₄H₂Br₂S

2,5-Dichlorothiophene chemical structure, C4H2Cl2S, CAS 3172-52-9

2,5-Dichlorothiophene

CAS 3172-52-9C₄H₂Cl₂S

2-Iodothiophene chemical structure, C4H3IS, CAS 3437-95-4

2-Iodothiophene

CAS 3437-95-4C₄H₃IS