Murcko scaffold
Ring system with 4 rings and 25 atoms
15 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 15
- With full pages
- 2
Scaffold SMILES
O=C(Nc1cc2c(s1)CNCC2)c1cccc(N2C(=O)CCC2=O)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 15 of 15 chemicals
![Ethyl 6-acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H23N3O6S, CAS 921133-63-3](/s/XIHQATXRACDPMR-UHFFFAOYSA-N.svg)
Ethyl 6-acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 921133-63-3C23H23N3O6S
![6-Acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C21H20N4O5S, CAS 864927-82-2](/s/VFZXOUAYPCZKAE-UHFFFAOYSA-N.svg)
6-Acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 864927-82-2C21H20N4O5S
![Methyl 6-acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H21N3O6S, CAS 864857-90-9](/s/PKZLEKTZSSGYPB-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 864857-90-9C22H21N3O6S
![N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C21H18N4O4S, CAS 921138-72-9](/s/BHQYTZFUORXEEI-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 921138-72-9C21H18N4O4S
![Diethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C24H25N3O7S, CAS 921092-89-9](/s/DKPMQZXBXNMMQM-UHFFFAOYSA-N.svg)
Diethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 921092-89-9C24H25N3O7S
![Ethyl 3-cyano-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C22H20N4O5S, CAS 921052-17-7](/s/YYIXSVDQRWBPAD-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 921052-17-7C22H20N4O5S
![6-Ethyl 3-methyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C23H23N3O7S, CAS 921166-06-5](/s/QFVSVNMKMRKLIZ-UHFFFAOYSA-N.svg)
6-Ethyl 3-methyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 921166-06-5C23H23N3O7S
![Ethyl 3-carbamoyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C22H22N4O6S, CAS 921160-42-1](/s/FIXBNYVHAKDOTI-UHFFFAOYSA-N.svg)
Ethyl 3-carbamoyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 921160-42-1C22H22N4O6S
![2-(3-(2,5-Dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride chemical structure, C21H23ClN4O4S, CAS 1216557-45-7](/s/WQECTJDTVIQDAO-UHFFFAOYSA-N.svg)
2-(3-(2,5-Dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride
CAS 1216557-45-7C21H23ClN4O4S
![Methyl 3-carbamoyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C21H20N4O6S, CAS 886951-84-4](/s/VYZQAYAGCRRSKY-UHFFFAOYSA-N.svg)
Methyl 3-carbamoyl-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 886951-84-4C21H20N4O6S
![Methyl 2-[3-(2,5-dioxopyrrolidin-1-yl)benzamido]-3-(methylcarbamoyl)-4H,5H,6H,7H-thieno[2,3-c]pyridine-6-carboxylate chemical structure, C22H22N4O6S, CAS 886957-45-5](/s/LVAGQYSUSUYMSB-UHFFFAOYSA-N.svg)
Methyl 2-[3-(2,5-dioxopyrrolidin-1-yl)benzamido]-3-(methylcarbamoyl)-4H,5H,6H,7H-thieno[2,3-c]pyridine-6-carboxylate
CAS 886957-45-5C22H22N4O6S
![Methyl 3-cyano-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C21H18N4O5S, CAS 886955-33-5](/s/OWPPDFKGWSCEDS-UHFFFAOYSA-N.svg)
Methyl 3-cyano-2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 886955-33-5C21H18N4O5S
![Dimethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C22H21N3O7S, CAS 886939-77-1](/s/YIIPDVCKHITERO-UHFFFAOYSA-N.svg)
Dimethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 886939-77-1C22H21N3O7S
![Ethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride chemical structure, C23H26ClN3O5S, CAS 1135200-67-7](/s/LGCZDRJISHFUNY-UHFFFAOYSA-N.svg)
Ethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride
CAS 1135200-67-7C23H26ClN3O5S
![Methyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride chemical structure, C22H24ClN3O5S, CAS 1329840-45-0](/s/KRABTLWQLPQICR-UHFFFAOYSA-N.svg)
Methyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate hydrochloride
CAS 1329840-45-0C22H24ClN3O5S
Related scaffolds
Same ring framework with different atoms or bond orders
