Murcko scaffold
N-(1,3-Benzothiazol-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)benzamide scaffold
90 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 90
- With full pages
- 11
Scaffold SMILES
O=C(Nc1nc2ccccc2s1)c1cccc(N2C(=O)CCC2=O)c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 90 chemicals
N-(1,3-Benzothiazol-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 314043-88-4C18H13N3O3S
![(E)-N-(4-Chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H14ClN3O3S, CAS 865543-89-1](/s/VGQAGRUEYRXNGJ-UHFFFAOYSA-N.svg)
(E)-N-(4-Chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 865543-89-1C19H14ClN3O3S
![(Z)-N-(4,6-Dichloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H13Cl2N3O3S, CAS 868369-90-8](/s/HCVMFIMOPDBYMP-UHFFFAOYSA-N.svg)
(Z)-N-(4,6-Dichloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868369-90-8C19H13Cl2N3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,5,7-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C21H19N3O3S, CAS 868369-91-9](/s/OYAFIEJUVBVCPL-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,5,7-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868369-91-9C21H19N3O3S
3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,4,7-trimethyl-1,3-benzothiazol-2-ylidene)benzamide
CAS 1321774-58-6C21H19N3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3,7-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C21H19N3O4S, CAS 868369-93-1](/s/GHGGCQZSFBRNAS-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3,7-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868369-93-1C21H19N3O4S
![(Z)-N-(4,7-Dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C21H19N3O5S, CAS 1164509-13-0](/s/GDEOVZOGQUWNTL-UHFFFAOYSA-N.svg)
(Z)-N-(4,7-Dimethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 1164509-13-0C21H19N3O5S
![(Z)-N-(7-Chloro-3,4-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C20H16ClN3O3S, CAS 868369-95-3](/s/QHCSLCKZLNICDD-UHFFFAOYSA-N.svg)
(Z)-N-(7-Chloro-3,4-dimethylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868369-95-3C20H16ClN3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-5,7-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H21N3O3S, CAS 868369-96-4](/s/KFXCTSOJNJDXHX-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-5,7-dimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868369-96-4C22H21N3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4-methoxy-7-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H21N3O4S, CAS 868369-97-5](/s/PYZFHZVRTDQMSD-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4-methoxy-7-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868369-97-5C22H21N3O4S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4,7-dimethoxybenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C22H21N3O5S, CAS 868369-98-6](/s/OWWZTGBECYAHPL-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4,7-dimethoxybenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868369-98-6C22H21N3O5S
![(Z)-N-(4,6-Difluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C19H13F2N3O3S, CAS 868375-22-8](/s/IAUJMVDRFDVJCN-UHFFFAOYSA-N.svg)
(Z)-N-(4,6-Difluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868375-22-8C19H13F2N3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4,6-difluorobenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C20H15F2N3O3S, CAS 868375-23-9](/s/OWGFNYMDGLWYPX-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4,6-difluorobenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868375-23-9C20H15F2N3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C19H14FN3O3S, CAS 868375-24-0](/s/HWZQELHXXYNCDJ-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868375-24-0C19H14FN3O3S
![(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C20H16FN3O3S, CAS 868375-25-1](/s/APJFZJNWOSPTBY-UHFFFAOYSA-N.svg)
(Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 868375-25-1C20H16FN3O3S
![(Z)-N-(3-Allyl-4-methoxybenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C22H19N3O4S, CAS 868376-47-0](/s/LNNAXVNMELJEBO-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-4-methoxybenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868376-47-0C22H19N3O4S
![(Z)-N-(3-Allyl-4-ethoxybenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide chemical structure, C23H21N3O4S, CAS 868376-48-1](/s/ZXPKAHGUFTYTPZ-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-4-ethoxybenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868376-48-1C23H21N3O4S
N-(5,7-Dimethyl-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868674-12-8C23H19N3O3S
3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)benzamide
CAS 868674-13-9C22H17N3O4S
3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-ethoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)benzamide
CAS 868674-14-0C23H19N3O4S
3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methyl-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)benzamide
CAS 868674-15-1C22H17N3O3S
N-(4-Chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide
CAS 868674-16-2C21H14ClN3O3S
![Ethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)benzo[d]thiazole-6-carboxylate chemical structure, C21H17N3O5S, CAS 311327-58-9](/s/UWRSYVOJLHKBDU-UHFFFAOYSA-N.svg)
Ethyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)benzo[d]thiazole-6-carboxylate
CAS 311327-58-9C21H17N3O5S
![(E)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(6-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C19H14FN3O3S, CAS 477295-08-2](/s/SXRHPCRCDPYOGY-UHFFFAOYSA-N.svg)
(E)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(6-fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 477295-08-2C19H14FN3O3S
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-prop-2-ynyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)benzamide865182-26-9C21H16N4O5S2
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-(2-ethoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide865173-95-1C22H22N4O6S2
- (Z)-Methyl 2-(2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate865198-98-7C21H18N4O7S2
- N-(4,5-Dimethyl-1,3-benzothiazol-2-yl)-3-(2,5-dioxopyrrolidin-1-yl)benzamide864860-79-7C20H17N3O3S
- (Z)-Methyl 2-(2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-6-fluorobenzo[d]thiazol-3(2H)-yl)acetate865198-19-2C21H16FN3O5S
- (E)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3,4,6-trimethylbenzo[d]thiazol-2(3H)-ylidene)benzamide681163-76-8C21H19N3O3S
- (Z)-N-(3-Allyl-6-chlorobenzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide941871-49-4C21H16ClN3O3S
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)benzamide897616-31-8C22H21N3O4S
- (Z)-Methyl 3-allyl-2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-2,3-dihydrobenzo[d]thiazole-6-carboxylate941976-63-2C23H19N3O5S
- Methyl 2-(3-(2,5-dioxopyrrolidin-1-yl)benzamido)benzo[d]thiazole-6-carboxylate864860-54-8C20H15N3O5S
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-(2-methoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide865160-22-1C21H20N4O6S2
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-(2-ethoxyethyl)-6-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide897616-35-2C22H20FN3O4S
- (E)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide477295-06-0C20H17N3O4S
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide476321-51-4C19H15N3O4S
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(6-ethoxy-1,3-benzothiazol-2-yl)benzamide476321-52-5C20H17N3O4S
- (Z)-N-(6-Chloro-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide941917-06-2C21H14ClN3O3S
- Ethyl 2-[2-[3-(2,5-dioxopyrrolidin-1-yl)benzoyl]imino-1,3-benzothiazol-3-yl]acetate865247-00-3C22H19N3O5S
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(6-ethoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide391867-69-9C21H19N3O4S
- (Z)-3-(2,5-Dioxopyrrolidin-1-yl)-N-(3-(2-ethoxyethyl)-6-methylbenzo[d]thiazol-2(3H)-ylidene)benzamide897616-28-3C23H23N3O4S
- (Z)-N-(6-Bromo-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-3-(2,5-dioxopyrrolidin-1-yl)benzamide865181-36-8C21H14BrN3O3S
- (Z)-Methyl 2-(2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-6-methylbenzo[d]thiazol-3(2H)-yl)acetate865197-38-2C22H19N3O5S
- (Z)-Ethyl 2-(2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-4-fluorobenzo[d]thiazol-3(2H)-yl)acetate865249-16-7C22H18FN3O5S
- (Z)-Methyl 2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)-3-(prop-2-yn-1-yl)-2,3-dihydrobenzo[d]thiazole-6-carboxylate941976-94-9C23H17N3O5S
- (Z)-Methyl 2-(6-acetamido-2-((3-(2,5-dioxopyrrolidin-1-yl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate941917-37-9C23H20N4O6S
Related scaffolds
Same ring framework with different atoms or bond orders
