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Murcko scaffold

Ring system with 4 rings and 22 atoms

46 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
46
With full pages
2
Scaffold SMILES

C(=NNc1nnc2c(n1)[nH]c1ccccc12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NNc1nnc2c(n1)[nH]c1ccccc12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

(Z)-1-[(2,5-Dimethoxyphenyl)methylidene]-2-{6-methyl-5H-[1,2,4]triazino[5,6-B]indol-3-YL}hydrazine chemical structure, C19H18N6O2
(Z)-1-[(2,5-Dimethoxyphenyl)methylidene]-2-{6-methyl-5H-[1,2,4]triazino[5,6-B]indol-3-YL}hydrazine
C19H18N6O2
4-(Dipropylamino)benzaldehyde (6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C23H27N7, CAS 330446-22-5
4-(Dipropylamino)benzaldehyde (6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone
CAS 330446-22-5C23H27N7
(Z)-3-(2-(2,5-Dimethoxybenzylidene)hydrazinyl)-6-methyl-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C19H18N6O2, CAS 327032-34-8
(Z)-3-(2-(2,5-Dimethoxybenzylidene)hydrazinyl)-6-methyl-5H-[1,2,4]triazino[5,6-b]indole
CAS 327032-34-8C19H18N6O2
N-[(Z)-(2,4-Dimethoxyphenyl)methylideneamino]-6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-amine chemical structure, C19H18N6O2, CAS 5619-91-0
N-[(Z)-(2,4-Dimethoxyphenyl)methylideneamino]-6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-amine
CAS 5619-91-0C19H18N6O2
4-(2-Hydroxyethoxy)-3-methoxybenzaldehyde 2-(5H-1,2,4-triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C19H18N6O3, CAS 486995-10-2
4-(2-Hydroxyethoxy)-3-methoxybenzaldehyde 2-(5H-1,2,4-triazino[5,6-b]indol-3-yl)hydrazone
CAS 486995-10-2C19H18N6O3
4-Chlorobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C16H11ClN6, CAS 5491-93-0
4-Chlorobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 5491-93-0C16H11ClN6
2,4-Dimethoxybenzaldehyde (8-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C19H18N6O2, CAS 418801-18-0
2,4-Dimethoxybenzaldehyde (8-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone
CAS 418801-18-0C19H18N6O2
4-Methoxybenzaldehyde (5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C18H16N6O, CAS 113361-47-0
4-Methoxybenzaldehyde (5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone
CAS 113361-47-0C18H16N6O
5-Ethyl-3-[(2E)-2-(4-methoxybenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C19H18N6O, CAS 133665-44-8
5-Ethyl-3-[(2E)-2-(4-methoxybenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole
CAS 133665-44-8C19H18N6O
4-(Dimethylamino)benzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C18H17N7, CAS 113306-11-9
4-(Dimethylamino)benzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 113306-11-9C18H17N7
8-Bromo-3-[(2E)-2-(3-nitrobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C16H10BrN7O2, CAS 371943-02-1
8-Bromo-3-[(2E)-2-(3-nitrobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole
CAS 371943-02-1C16H10BrN7O2
5-Ethyl-3-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C18H15IN6, CAS 5305-32-8
5-Ethyl-3-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole
CAS 5305-32-8C18H15IN6
8-Bromo-N-[(E)-(2,4-dichlorophenyl)methylideneamino]-5H-[1,2,4]triazino[5,6-b]indol-3-amine chemical structure, C16H9BrCl2N6, CAS 5305-36-2
8-Bromo-N-[(E)-(2,4-dichlorophenyl)methylideneamino]-5H-[1,2,4]triazino[5,6-b]indol-3-amine
CAS 5305-36-2C16H9BrCl2N6
5-Ethyl-3-[(2E)-2-(4-nitrobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole chemical structure, C18H15N7O2, CAS 320740-55-4
5-Ethyl-3-[(2E)-2-(4-nitrobenzylidene)hydrazinyl]-5H-[1,2,4]triazino[5,6-b]indole
CAS 320740-55-4C18H15N7O2
3-Nitrobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C16H11N7O2, CAS 302795-54-6
3-Nitrobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 302795-54-6C16H11N7O2
4-Bromobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C16H11BrN6, CAS 319491-05-9
4-Bromobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 319491-05-9C16H11BrN6
N-(2,4-Dichloro-benzylidene)-N'-(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazine chemical structure, C16H10Cl2N6, CAS 319491-06-0
N-(2,4-Dichloro-benzylidene)-N'-(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazine
CAS 319491-06-0C16H10Cl2N6
4-{(E)-[2-(8-Bromo-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazinylidene]methyl}-N,N-dimethylaniline chemical structure, C18H16BrN7, CAS 113387-47-6
4-{(E)-[2-(8-Bromo-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazinylidene]methyl}-N,N-dimethylaniline
CAS 113387-47-6C18H16BrN7
4-Bromobenzaldehyde (5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C18H15BrN6, CAS 320583-47-9
4-Bromobenzaldehyde (5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone
CAS 320583-47-9C18H15BrN6
2-Nitrobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C16H11N7O2, CAS 352520-31-1
2-Nitrobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 352520-31-1C16H11N7O2
4-Methylbenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C17H14N6, CAS 129074-85-7
4-Methylbenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 129074-85-7C17H14N6
3-Chlorobenzaldehyde (8-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone chemical structure, C17H13ClN6, CAS 331263-33-3
3-Chlorobenzaldehyde (8-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)hydrazone
CAS 331263-33-3C17H13ClN6
3-Chlorobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone chemical structure, C16H11ClN6, CAS 324029-89-2
3-Chlorobenzaldehyde 5H-[1,2,4]triazino[5,6-b]indol-3-ylhydrazone
CAS 324029-89-2C16H11ClN6
N-(3-Bromo-benzylidene)-N'-(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazine chemical structure, C16H11BrN6, CAS 322413-52-5
N-(3-Bromo-benzylidene)-N'-(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazine
CAS 322413-52-5C16H11BrN6