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Murcko scaffold

Ring system with 4 rings and 24 atoms

40 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 24
Chemicals: 40
With full pages: 4

Scaffold SMILES

O=C(Cn1cnc2c(oc3ccccc32)c1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Cn1cnc2c(oc3ccccc32)c1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

N-(5-Chloro-2-methoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C19H14ClN3O4, CAS 850259-00-6

N-(5-Chloro-2-methoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850259-00-6C₁₉H₁₄ClN₃O₄

N-(4-Methoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C19H15N3O4, CAS 850371-54-9

N-(4-Methoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850371-54-9C₁₉H₁₅N₃O₄

N-(2,4-Dimethoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H17N3O5, CAS 864923-09-1

N-(2,4-Dimethoxyphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 864923-09-1C₂₀H₁₇N₃O₅

N-(3,4-Dimethoxyphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C20H17N3O5, CAS 864923-10-4

N-(3,4-Dimethoxyphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 864923-10-4C₂₀H₁₇N₃O₅

2-(4-Oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)-N-(2-(trifluoromethyl)phenyl)acetamide chemical structure, C19H12F3N3O3, CAS 849678-29-1

2-(4-Oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)-N-(2-(trifluoromethyl)phenyl)acetamide

CAS 849678-29-1C₁₉H₁₂F₃N₃O₃

$2-{6-Oxo-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen-5-yl}-N-[4-(trifluoromethyl)phenyl]acetamide chemical structure, C19H12F3N3O3, CAS 864923-13-7$

2-{6-Oxo-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen-5-yl}-N-[4-(trifluoromethyl)phenyl]acetamide

CAS 864923-13-7C₁₉H₁₂F₃N₃O₃

2-(4-Oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide chemical structure, C19H12F3N3O4, CAS 849616-63-3

2-(4-Oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide

CAS 849616-63-3C₁₉H₁₂F₃N₃O₄

N-(3-Acetylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C20H15N3O4, CAS 850632-91-6

N-(3-Acetylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850632-91-6C₂₀H₁₅N₃O₄

N-(3-Chloro-4-fluorophenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C18H11ClFN3O3, CAS 849532-89-4

N-(3-Chloro-4-fluorophenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 849532-89-4C₁₈H₁₁ClFN₃O₃

N-(3,4-Dichlorophenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C18H11Cl2N3O3, CAS 849528-82-1

N-(3,4-Dichlorophenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 849528-82-1C₁₈H₁₁Cl₂N₃O₃

N-(3,4-Dimethylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C20H17N3O3, CAS 850625-99-9

N-(3,4-Dimethylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850625-99-9C₂₀H₁₇N₃O₃

2-(4-Oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)-N-(4-propan-2-ylphenyl)acetamide chemical structure, C21H19N3O3, CAS 850590-33-9

2-(4-Oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)-N-(4-propan-2-ylphenyl)acetamide

CAS 850590-33-9C₂₁H₁₉N₃O₃

N-(2,6-Dimethylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C20H17N3O3, CAS 850540-23-7

N-(2,6-Dimethylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850540-23-7C₂₀H₁₇N₃O₃

N-(3-Bromophenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C18H12BrN3O3, CAS 849185-82-6

N-(3-Bromophenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 849185-82-6C₁₈H₁₂BrN₃O₃

N-(4-Bromo-3-methylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C19H14BrN3O3, CAS 850182-80-8

N-(4-Bromo-3-methylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850182-80-8C₁₉H₁₄BrN₃O₃

N-(3-Chloro-4-methoxyphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C19H14ClN3O4, CAS 850370-61-5

N-(3-Chloro-4-methoxyphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850370-61-5C₁₉H₁₄ClN₃O₄

N-(3-Fluoro-4-methylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide chemical structure, C19H14FN3O3, CAS 850703-42-3

N-(3-Fluoro-4-methylphenyl)-2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetamide

CAS 850703-42-3C₁₉H₁₄FN₃O₃

N-(3-Acetamidophenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H16N4O4, CAS 864923-17-1

N-(3-Acetamidophenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 864923-17-1C₂₀H₁₆N₄O₄

N-(2,3-Dimethylphenyl)-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H17N3O3, CAS 850651-98-8

N-(2,3-Dimethylphenyl)-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850651-98-8C₂₀H₁₇N₃O₃

N-(2,5-Dimethylphenyl)-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H17N3O3, CAS 850462-11-2

N-(2,5-Dimethylphenyl)-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850462-11-2C₂₀H₁₇N₃O₃

N-(3,5-Dimethylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H17N3O3, CAS 850169-16-3

N-(3,5-Dimethylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850169-16-3C₂₀H₁₇N₃O₃

N-Mesityl-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C21H19N3O3, CAS 849687-71-4

N-Mesityl-2-(4-oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 849687-71-4C₂₁H₁₉N₃O₃

N-(4-Ethylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C20H17N3O3, CAS 850556-47-7

N-(4-Ethylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850556-47-7C₂₀H₁₇N₃O₃

N-(4-Butylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide chemical structure, C22H21N3O3, CAS 850601-99-9

N-(4-Butylphenyl)-2-(4-oxobenzofuro[3,2-d]pyrimidin-3(4H)-yl)acetamide

CAS 850601-99-9C₂₂H₂₁N₃O₃