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Murcko scaffold

Ring system with 4 rings and 26 atoms

39 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 26
Chemicals: 39
With full pages: 3

Scaffold SMILES

O=C(c1cc2ccccc2s1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(c1cc2ccccc2s1)N(Cc1ccccc1)C1CCS(=O)(=O)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide chemical structure, C23H24ClNO3S2, CAS 577763-10-1

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide

CAS 577763-10-1C₂₃H₂₄ClNO₃S₂

3,4,6-Trichloro-N-(3,4-dimethoxybenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C22H20Cl3NO5S2, CAS 578751-35-6

3,4,6-Trichloro-N-(3,4-dimethoxybenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 578751-35-6C₂₂H₂₀Cl₃NO₅S₂

3-Chloro-N-(2-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H17Cl2NO3S2, CAS 578733-96-7

3-Chloro-N-(2-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 578733-96-7C₂₀H₁₇Cl₂NO₃S₂

Benzo[B]thiophene-2-carboxamide, 3,4-dichloro-N-[[4-(dimethylamino)phenyl]methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)- chemical structure, C22H22Cl2N2O3S2, CAS 587009-60-7

Benzo[B]thiophene-2-carboxamide, 3,4-dichloro-N-[[4-(dimethylamino)phenyl]methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)-

CAS 587009-60-7C₂₂H₂₂Cl₂N₂O₃S₂

3-Chloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H17Cl2NO3S2, CAS 620568-28-7

3-Chloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 620568-28-7C₂₀H₁₇Cl₂NO₃S₂

N-Benzyl-3-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H18ClNO3S2, CAS 620567-29-5

N-Benzyl-3-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 620567-29-5C₂₀H₁₈ClNO₃S₂

3,4,6-Trichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide chemical structure, C23H22Cl3NO3S2, CAS 620571-26-8

3,4,6-Trichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide

CAS 620571-26-8C₂₃H₂₂Cl₃NO₃S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-6-methyl-1-benzothiophene-2-carboxamide chemical structure, C22H22ClNO4S2, CAS 620567-85-3

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-6-methyl-1-benzothiophene-2-carboxamide

CAS 620567-85-3C₂₂H₂₂ClNO₄S₂

3-Chloro-N-(3-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H17Cl2NO3S2, CAS 577983-62-1

3-Chloro-N-(3-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 577983-62-1C₂₀H₁₇Cl₂NO₃S₂

N-Benzyl-3,6-dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H17Cl2NO3S2, CAS 620567-40-0

N-Benzyl-3,6-dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 620567-40-0C₂₀H₁₇Cl₂NO₃S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-1-benzothiophene-2-carboxamide chemical structure, C22H22ClNO3S2, CAS 620569-85-9

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-1-benzothiophene-2-carboxamide

CAS 620569-85-9C₂₂H₂₂ClNO₃S₂

Benzo[b]thiophene-2-carboxamide, 3,4,6-trichloro-N-[(4-chlorophenyl)methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)-(9CI) chemical structure, C20H15Cl4NO3S2, CAS 587004-34-0

Benzo[b]thiophene-2-carboxamide, 3,4,6-trichloro-N-[(4-chlorophenyl)methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)-(9CI)

CAS 587004-34-0C₂₀H₁₅Cl₄NO₃S₂

3,4-Dichloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H16Cl3NO3S2, CAS 573936-72-8

3,4-Dichloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 573936-72-8C₂₀H₁₆Cl₃NO₃S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-6-methyl-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide chemical structure, C24H26ClNO3S2, CAS 587003-20-1

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-6-methyl-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide

CAS 587003-20-1C₂₄H₂₆ClNO₃S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-6-methyl-1-benzothiophene-2-carboxamide chemical structure, C23H24ClNO3S2, CAS 578718-25-9

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-ethylbenzyl)-6-methyl-1-benzothiophene-2-carboxamide

CAS 578718-25-9C₂₃H₂₄ClNO₃S₂

3-Chloro-N-(3-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-6-methyl-1-benzothiophene-2-carboxamide chemical structure, C21H19Cl2NO3S2, CAS 575470-41-6

3-Chloro-N-(3-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-6-methyl-1-benzothiophene-2-carboxamide

CAS 575470-41-6C₂₁H₁₉Cl₂NO₃S₂

N-Benzyl-3,4-dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H17Cl2NO3S2, CAS 620567-45-5

N-Benzyl-3,4-dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 620567-45-5C₂₀H₁₇Cl₂NO₃S₂

3-Chloro-N-[4-(dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C22H23ClN2O3S2, CAS 620571-66-6

3-Chloro-N-[4-(dimethylamino)benzyl]-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 620571-66-6C₂₂H₂₃ClN₂O₃S₂

3,6-Dichloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H16Cl3NO3S2, CAS 575462-41-8

3,6-Dichloro-N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 575462-41-8C₂₀H₁₆Cl₃NO₃S₂

3,6-Dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide chemical structure, C23H23Cl2NO3S2, CAS 575469-38-4

3,6-Dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[4-(propan-2-yl)benzyl]-1-benzothiophene-2-carboxamide

CAS 575469-38-4C₂₃H₂₃Cl₂NO₃S₂

N-Benzyl-3,4,6-trichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide chemical structure, C20H16Cl3NO3S2, CAS 578759-14-5

N-Benzyl-3,4,6-trichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-1-benzothiophene-2-carboxamide

CAS 578759-14-5C₂₀H₁₆Cl₃NO₃S₂

3,6-Dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-1-benzothiophene-2-carboxamide chemical structure, C21H19Cl2NO4S2, CAS 620567-91-1

3,6-Dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-1-benzothiophene-2-carboxamide

CAS 620567-91-1C₂₁H₁₉Cl₂NO₄S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-1-benzothiophene-2-carboxamide chemical structure, C21H20ClNO4S2, CAS 620567-80-8

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methoxybenzyl)-1-benzothiophene-2-carboxamide

CAS 620567-80-8C₂₁H₂₀ClNO₄S₂

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)-6-methyl-1-benzothiophene-2-carboxamide chemical structure, C21H19ClFNO3S2, CAS 848681-79-8

3-Chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)-6-methyl-1-benzothiophene-2-carboxamide

CAS 848681-79-8C₂₁H₁₉ClFNO₃S₂