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Murcko scaffold

Ring system with 3 rings and 21 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
27
With full pages
3
Scaffold SMILES

c1ccc(CCCNCc2cccc3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCCNCc2cccc3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

Cinacalcet hydrochloride chemical structure, C22H23ClF3N, CAS 364782-34-3
Cinacalcet hydrochloride
CAS 364782-34-3C22H23ClF3N
Cinacalcet chemical structure, C22H22F3N, CAS 226256-56-0
Cinacalcet
CAS 226256-56-0C22H22F3N
alpha-[2-[Methyl(1-naphthalenylmethyl)amino]ethyl]-Benzenemethanol chemical structure, C21H23NO, CAS 98977-94-7
alpha-[2-[Methyl(1-naphthalenylmethyl)amino]ethyl]-Benzenemethanol
CAS 98977-94-7C21H23NO
N-[(1R)-1-Naphthalen-1-ylethyl]-3-phenylpropan-1-amine chemical structure, C21H23N, CAS 253337-26-7
N-[(1R)-1-Naphthalen-1-ylethyl]-3-phenylpropan-1-amine
CAS 253337-26-7C21H23N
4-Methyl-I+/--[2-[methyl(1-naphthalenylmethyl)amino]ethyl]benzenemethanol chemical structure, C22H25NO, CAS 65473-19-0
4-Methyl-I+/--[2-[methyl(1-naphthalenylmethyl)amino]ethyl]benzenemethanol
CAS 65473-19-0C22H25NO
(S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine chemical structure, C22H22F3N, CAS 694495-47-1
(S)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine
CAS 694495-47-1C22H22F3N
(R)-Cinacalcet-D3 chemical structure, C22H22F3N, CAS 1228567-12-1
(R)-Cinacalcet-D3
CAS 1228567-12-1C22H22F3N
rac Cinacalcet-d3 Hydrochloride chemical structure, C22H23ClF3N, CAS 1185097-33-9
rac Cinacalcet-d3 Hydrochloride
CAS 1185097-33-9C22H23ClF3N
N-[(1S)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine hydrochloride chemical structure, C22H23ClF3N, CAS 1217809-88-5
N-[(1S)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-propanamine hydrochloride
CAS 1217809-88-5C22H23ClF3N
3-(((R)-1-(Naphthalen-1-yl)ethyl)amino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol chemical structure, C22H22F3NO, CAS 1224568-02-8
3-(((R)-1-(Naphthalen-1-yl)ethyl)amino)-1-(3-(trifluoromethyl)phenyl)propan-1-ol
CAS 1224568-02-8C22H22F3NO
rac Cinacalcet HCl chemical structure, C22H23ClF3N, CAS 1025064-33-8
rac Cinacalcet HCl
CAS 1025064-33-8C22H23ClF3N
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(m-tolyl)propan-1-amine chemical structure, C22H25N, CAS 253337-60-9
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(m-tolyl)propan-1-amine
CAS 253337-60-9C22H25N
3-[3-(Difluoromethyl)phenyl]-N-(1-naphthalen-1-ylethyl)propan-1-amine chemical structure, C22H23F2N
3-[3-(Difluoromethyl)phenyl]-N-(1-naphthalen-1-ylethyl)propan-1-amine
C22H23F2N
3'-Destrifluoromethyl 2'-trifluoromethyl cinacalcet hydrochloride chemical structure, C22H23ClF3N, CAS 2469242-96-2
3'-Destrifluoromethyl 2'-trifluoromethyl cinacalcet hydrochloride
CAS 2469242-96-2C22H23ClF3N
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine chemical structure, C22H22F3N, CAS 1431699-53-4
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(2-(trifluoromethyl)phenyl)propan-1-amine
CAS 1431699-53-4C22H22F3N
(R)-3-(3-(Difluoromethyl)phenyl)-N-(1-(naphthalen-1-yl)ethyl)propan-1-amine chemical structure, C22H23F2N, CAS 1025064-41-8
(R)-3-(3-(Difluoromethyl)phenyl)-N-(1-(naphthalen-1-yl)ethyl)propan-1-amine
CAS 1025064-41-8C22H23F2N
N-(1-Naphthalen-1-ylethyl)-3-[2-(trifluoromethyl)phenyl]propan-1-amine chemical structure, C22H22F3N
N-(1-Naphthalen-1-ylethyl)-3-[2-(trifluoromethyl)phenyl]propan-1-amine
C22H22F3N
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine chemical structure, C22H22F3N, CAS 1428185-71-0
(R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(4-(trifluoromethyl)phenyl)propan-1-amine
CAS 1428185-71-0C22H22F3N
Cinacalcet N-oxide chemical structure, C22H22F3NO, CAS 1229224-94-5
Cinacalcet N-oxide
CAS 1229224-94-5C22H22F3NO
Cinacalcet-d3 (hydrochloride) chemical structure, C22H23ClF3N, CAS 2749807-20-1
Cinacalcet-d3 (hydrochloride)
CAS 2749807-20-1C22H23ClF3N
Cinacalcet-d4 hydrochloride chemical structure, C22H23ClF3N, CAS 2514927-75-2
Cinacalcet-d4 hydrochloride
CAS 2514927-75-2C22H23ClF3N
(S)-Cinacalcet-D3 hydrochloride chemical structure, C22H23ClF3N, CAS 2673269-84-4
(S)-Cinacalcet-D3 hydrochloride
CAS 2673269-84-4C22H23ClF3N
(AlphaR)-alpha-methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine hydrochloride salt chemical structure, C22H23ClF3N, CAS 1428118-39-1
(AlphaR)-alpha-methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine hydrochloride salt
CAS 1428118-39-1C22H23ClF3N
N-Nitroso-cinacalcet chemical structure, C22H21F3N2O, CAS 3036581-83-3
N-Nitroso-cinacalcet
CAS 3036581-83-3C22H21F3N2O