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Murcko scaffold

Ring system with 3 rings and 24 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(COC(=O)c1n[nH]c(=O)c2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1n[nH]c(=O)c2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

[2-[2-(Difluoromethoxy)anilino]-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C19H15F2N3O5, CAS 729566-98-7
[2-[2-(Difluoromethoxy)anilino]-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 729566-98-7C19H15F2N3O5
[2-Oxo-2-(4-propan-2-ylanilino)ethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C21H21N3O4, CAS 742112-70-5
[2-Oxo-2-(4-propan-2-ylanilino)ethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 742112-70-5C21H21N3O4
[2-(3-Fluoro-4-methylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C19H16FN3O4, CAS 848228-74-0
[2-(3-Fluoro-4-methylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 848228-74-0C19H16FN3O4
[2-(2,3-Dimethylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C20H19N3O4, CAS 848321-13-1
[2-(2,3-Dimethylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 848321-13-1C20H19N3O4
[2-(2-Chloro-4-fluoroanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C18H13ClFN3O4, CAS 848581-47-5
[2-(2-Chloro-4-fluoroanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 848581-47-5C18H13ClFN3O4
[2-(2,5-Dimethylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C20H19N3O4, CAS 863763-23-9
[2-(2,5-Dimethylanilino)-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 863763-23-9C20H19N3O4
[2-[4-(Difluoromethylsulfanyl)anilino]-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate chemical structure, C19H15F2N3O4S, CAS 805289-03-6
[2-[4-(Difluoromethylsulfanyl)anilino]-2-oxoethyl] 3-methyl-4-oxophthalazine-1-carboxylate
CAS 805289-03-6C19H15F2N3O4S
[2-(3,4-Dichloroanilino)-2-oxoethyl] 3-(2-hydroxyethyl)-4-oxophthalazine-1-carboxylate chemical structure, C19H15Cl2N3O5, CAS 732989-62-7
[2-(3,4-Dichloroanilino)-2-oxoethyl] 3-(2-hydroxyethyl)-4-oxophthalazine-1-carboxylate
CAS 732989-62-7C19H15Cl2N3O5
[2-(4-Carbamoylanilino)-2-oxoethyl] 4-oxo-3-propylphthalazine-1-carboxylate chemical structure, C21H20N4O5, CAS 743453-93-2
[2-(4-Carbamoylanilino)-2-oxoethyl] 4-oxo-3-propylphthalazine-1-carboxylate
CAS 743453-93-2C21H20N4O5
[2-Oxo-2-[3-(trifluoromethyl)anilino]ethyl] 4-oxo-3H-phthalazine-1-carboxylate chemical structure, C18H12F3N3O4, CAS 385398-65-2
[2-Oxo-2-[3-(trifluoromethyl)anilino]ethyl] 4-oxo-3H-phthalazine-1-carboxylate
CAS 385398-65-2C18H12F3N3O4
2-[(3,4-Dimethylphenyl)amino]-2-oxoethyl 3,4-dihydro-4-oxo-1-phthalazinecarboxylate chemical structure, C19H17N3O4, CAS 385398-79-8
2-[(3,4-Dimethylphenyl)amino]-2-oxoethyl 3,4-dihydro-4-oxo-1-phthalazinecarboxylate
CAS 385398-79-8C19H17N3O4
[2-(4-Methylanilino)-2-oxoethyl] 4-oxo-3H-phthalazine-1-carboxylate chemical structure, C18H15N3O4, CAS 385399-26-8
[2-(4-Methylanilino)-2-oxoethyl] 4-oxo-3H-phthalazine-1-carboxylate
CAS 385399-26-8C18H15N3O4
[(Cyanomethyl)(phenyl)carbamoyl]methyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate chemical structure, C19H14N4O4, CAS 1031529-38-0
[(Cyanomethyl)(phenyl)carbamoyl]methyl 4-oxo-3,4-dihydrophthalazine-1-carboxylate
CAS 1031529-38-0C19H14N4O4