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Murcko scaffold

Ring system with 2 rings and 9 atoms

45 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 45
With full pages: 9

Scaffold SMILES

c1ncc2c(n1)COC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ncc2c(n1)COC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2-Methyl-5,7-dihydrofuro[3,4-d]pyrimidine chemical structure, C7H8N2O, CAS 36267-74-0

2-Methyl-5,7-dihydrofuro[3,4-d]pyrimidine

CAS 36267-74-0C₇H₈N₂O

2,7-Dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine chemical structure, C8H10N2O, CAS 36267-77-3

2,7-Dimethyl-5,7-dihydrofuro[3,4-d]pyrimidine

CAS 36267-77-3C₈H₁₀N₂O

4-Chloro-2-methyl-5H,7H-furo[3,4-D]pyrimidine chemical structure, C7H7ClN2O, CAS 36267-73-9

4-Chloro-2-methyl-5H,7H-furo[3,4-D]pyrimidine

CAS 36267-73-9C₇H₇ClN₂O

2,4-Dichloro-5H,7H-furo[3,4-d]pyrimidine chemical structure, C6H4Cl2N2O, CAS 848398-41-4

2,4-Dichloro-5H,7H-furo[3,4-d]pyrimidine

CAS 848398-41-4C₆H₄Cl₂N₂O

2,4-Dichloro-7,7-dimethyl-5H,7H-furo[3,4-d]pyrimidine chemical structure, C8H8Cl2N2O, CAS 1260088-72-9

2,4-Dichloro-7,7-dimethyl-5H,7H-furo[3,4-d]pyrimidine

CAS 1260088-72-9C₈H₈Cl₂N₂O

5,7-Dihydrofuro[3,4-D]pyrimidin-2-ylmethanamine chemical structure, C7H9N3O, CAS 944903-79-1

5,7-Dihydrofuro[3,4-D]pyrimidin-2-ylmethanamine

CAS 944903-79-1C₇H₉N₃O

2-(Chloromethyl)-5,7-dihydrofuro[3,4-D]pyrimidine chemical structure, C7H7ClN2O, CAS 944899-77-8

2-(Chloromethyl)-5,7-dihydrofuro[3,4-D]pyrimidine

CAS 944899-77-8C₇H₇ClN₂O

4-Chloro-5-methyl-5,7-dihydrofuro[3,4-D]pyrimidine chemical structure, C7H7ClN2O, CAS 1000984-97-3

4-Chloro-5-methyl-5,7-dihydrofuro[3,4-D]pyrimidine

CAS 1000984-97-3C₇H₇ClN₂O

2-Chloro-5,5,7,7-tetramethyl-5H,7H-furo[3,4-d]pyrimidine chemical structure, C10H13ClN2O, CAS 951004-05-0

2-Chloro-5,5,7,7-tetramethyl-5H,7H-furo[3,4-d]pyrimidine

CAS 951004-05-0C₁₀H₁₃ClN₂O

4-Chloro-2-(methylthio)-5,7-dihydrofuro[3,4-D]pyrimidine chemical structure, C7H7ClN2OS, CAS 1007396-05-5

4-Chloro-2-(methylthio)-5,7-dihydrofuro[3,4-D]pyrimidine

CAS 1007396-05-5C₇H₇ClN₂OS

5,5,7,7-Tetramethyl-5H,7H-furo[3,4-d]pyrimidin-2-amine chemical structure, C10H15N3O, CAS 380622-76-4

5,5,7,7-Tetramethyl-5H,7H-furo[3,4-d]pyrimidin-2-amine

CAS 380622-76-4C₁₀H₁₅N₃O

2-(5,7-Dihydrofuro[3,4-D]pyrimidin-2-yl)ethanamine hydrochloride chemical structure, C8H12ClN3O, CAS 1196154-52-5

2-(5,7-Dihydrofuro[3,4-D]pyrimidin-2-yl)ethanamine hydrochloride

CAS 1196154-52-5C₈H₁₂ClN₃O

4-Chloro-5H,7H-furo(3,4-d)pyrimidine chemical structure, C6H5ClN2O, CAS 1379179-87-9

4-Chloro-5H,7H-furo(3,4-d)pyrimidine

CAS 1379179-87-9C₆H₅ClN₂O

4-Chloro-2-methoxy-5,7-dihydrofuro[3,4-D]pyrimidine chemical structure, C7H7ClN2O2, CAS 1393552-69-6

4-Chloro-2-methoxy-5,7-dihydrofuro[3,4-D]pyrimidine

CAS 1393552-69-6C₇H₇ClN₂O₂

4-Chloro-2-(trifluoromethyl)-5,7-dihydrofuro[3,4-D]pyrimidine chemical structure, C7H4ClF3N2O, CAS 1393540-59-4

4-Chloro-2-(trifluoromethyl)-5,7-dihydrofuro[3,4-D]pyrimidine

CAS 1393540-59-4C₇H₄ClF₃N₂O

2-Chloro-5H,7H-furo(3,4-d)pyrimidine chemical structure, C6H5ClN2O, CAS 1233932-44-9

2-Chloro-5H,7H-furo(3,4-d)pyrimidine

CAS 1233932-44-9C₆H₅ClN₂O

2,4-Dichloro-7-methyl-5,7-dihydrofuro[3,4-d]pyrimidine chemical structure, C7H6Cl2N2O, CAS 1429309-52-3

2,4-Dichloro-7-methyl-5,7-dihydrofuro[3,4-d]pyrimidine

CAS 1429309-52-3C₇H₆Cl₂N₂O

4-Bromo-5H,7H-furo(3,4-d)pyrimidine chemical structure, C6H5BrN2O, CAS 1517565-09-1

4-Bromo-5H,7H-furo(3,4-d)pyrimidine

CAS 1517565-09-1C₆H₅BrN₂O

4-Chloro-5,7-dihydrofuro[3,4-d]pyrimidin-2-amine chemical structure, C6H6ClN3O, CAS 1211527-13-7

4-Chloro-5,7-dihydrofuro[3,4-d]pyrimidin-2-amine

CAS 1211527-13-7C₆H₆ClN₃O

5,7-Dihydrofuro[3,4-d]pyrimidine-4-carboxylic acid chemical structure, C7H6N2O3, CAS 1537663-07-2

5,7-Dihydrofuro[3,4-d]pyrimidine-4-carboxylic acid

CAS 1537663-07-2C₇H₆N₂O₃

2-Chloro-5,7-dihydrofuro[3,4-d]pyrimidine-4-carboxylic acid chemical structure, C7H5ClN2O3, CAS 1504398-16-6

2-Chloro-5,7-dihydrofuro[3,4-d]pyrimidine-4-carboxylic acid

CAS 1504398-16-6C₇H₅ClN₂O₃

N-(4-Methyl-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)-beta-alanine chemical structure, C10H13N3O3, CAS 1782214-38-3

N-(4-Methyl-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)-beta-alanine

CAS 1782214-38-3C₁₀H₁₃N₃O₃

(S)-2,4-Dichloro-7-methyl-5,7-dihydrofuro[3,4-d]pyrimidine chemical structure, C7H6Cl2N2O, CAS 2730031-52-2

(S)-2,4-Dichloro-7-methyl-5,7-dihydrofuro[3,4-d]pyrimidine

CAS 2730031-52-2C₇H₆Cl₂N₂O

5H,7H-Furo(3,4-d)pyrimidin-2-amine chemical structure, C6H7N3O, CAS 1648750-00-8

5H,7H-Furo(3,4-d)pyrimidin-2-amine

CAS 1648750-00-8C₆H₇N₃O