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Murcko scaffold

Ring system with 4 rings and 23 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
5
With full pages
1
Scaffold SMILES

c1ccc(Nc2nc3nonc3nc2Nc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc3nonc3nc2Nc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Bam15 chemical structure, C16H10F2N6O, CAS 210302-17-3
Bam15
CAS 210302-17-3C16H10F2N6O
N~5~-(2-iodophenyl)-N~6~-(3-methylphenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine chemical structure, C17H13IN6O, CAS 312267-01-9
N~5~-(2-iodophenyl)-N~6~-(3-methylphenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
CAS 312267-01-9C17H13IN6O
(2-Chlorophenyl){6-[(2-chlorophenyl)amino](1,2,5-oxadiazolo[3,4-e]pyrazin-5-yl)}amine chemical structure, C16H10Cl2N6O, CAS 210302-02-6
(2-Chlorophenyl){6-[(2-chlorophenyl)amino](1,2,5-oxadiazolo[3,4-e]pyrazin-5-yl)}amine
CAS 210302-02-6C16H10Cl2N6O
5,6-Bis{2-nitroanilino}[1,2,5]oxadiazolo[3,4-b]pyrazine chemical structure, C16H10N8O5, CAS 210302-22-0
5,6-Bis{2-nitroanilino}[1,2,5]oxadiazolo[3,4-b]pyrazine
CAS 210302-22-0C16H10N8O5
N5-(4-Fluorophenyl)-N6-[3-(trifluoromethyl)phenyl][1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine chemical structure, C17H10F4N6O, CAS 392315-46-7
N5-(4-Fluorophenyl)-N6-[3-(trifluoromethyl)phenyl][1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine
CAS 392315-46-7C17H10F4N6O