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Murcko scaffold

1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine scaffold

57 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
57
With full pages
6
Scaffold SMILES

c1ccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine page
Murcko scaffold c1ccc(N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 57 chemicals

4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine chemical structure, C21H19ClN6, CAS 305337-65-9
4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine
CAS 305337-65-9C21H19ClN6
1-(3-Chlorophenyl)-4-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperazine chemical structure, C21H19ClN6, CAS 305337-67-1
1-(3-Chlorophenyl)-4-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperazine
CAS 305337-67-1C21H19ClN6
1-(2-Chlorophenyl)-4-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperazine chemical structure, C21H19ClN6, CAS 305337-69-3
1-(2-Chlorophenyl)-4-{1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperazine
CAS 305337-69-3C21H19ClN6
1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C21H20N6, CAS 393845-64-2
1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-64-2C21H20N6
1-(4-Chlorophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C21H18ClFN6, CAS 393845-78-8
1-(4-Chlorophenyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-78-8C21H18ClFN6
4-(4-(4-Fluorophenyl)piperazin-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C21H19FN6, CAS 393845-82-4
4-(4-(4-Fluorophenyl)piperazin-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-82-4C21H19FN6
1-(4-Methoxyphenyl)-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C22H22N6O, CAS 393845-66-4
1-(4-Methoxyphenyl)-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-66-4C22H22N6O
4-[4-(3-Methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine chemical structure, C22H22N6O, CAS 393845-97-1
4-[4-(3-Methoxyphenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine
CAS 393845-97-1C22H22N6O
1-(4-Chlorophenyl)-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine chemical structure, C21H18ClFN6, CAS 393845-83-5
1-(4-Chlorophenyl)-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine
CAS 393845-83-5C21H18ClFN6
1-(2,4-Dimethylphenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C23H23FN6, CAS 393845-81-3
1-(2,4-Dimethylphenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-81-3C23H23FN6
4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C23H24N6O, CAS 393846-05-4
4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393846-05-4C23H24N6O
1-(2,4-Dimethylphenyl)-4-[4-(4-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine chemical structure, C24H26N6O, CAS 393846-07-6
1-(2,4-Dimethylphenyl)-4-[4-(4-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine
CAS 393846-07-6C24H26N6O
4-[4-(2-Fluorophenyl)piperazin-1-yl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidine chemical structure, C22H21FN6O, CAS 393845-79-9
4-[4-(2-Fluorophenyl)piperazin-1-yl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidine
CAS 393845-79-9C22H21FN6O
1-(2,4-Dimethylphenyl)-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine chemical structure, C23H23FN6, CAS 393845-86-8
1-(2,4-Dimethylphenyl)-4-[4-(4-fluorophenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine
CAS 393845-86-8C23H23FN6
4-[4-(3-Chlorophenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine chemical structure, C22H21ClN6, CAS 393845-75-5
4-[4-(3-Chlorophenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine
CAS 393845-75-5C22H21ClN6
1-(4-Methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C23H24N6O2, CAS 393845-94-8
1-(4-Methoxyphenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-94-8C23H24N6O2
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine chemical structure, C23H24N6O, CAS 393845-95-9
4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine
CAS 393845-95-9C23H24N6O
4-[4-(2-Chlorophenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine chemical structure, C22H21ClN6, CAS 393845-71-1
4-[4-(2-Chlorophenyl)piperazin-1-yl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidine
CAS 393845-71-1C22H21ClN6
4-[4-(3,4-Dichlorophenyl)piperazinyl]-1-phenylpyrazolo[5,4-d]pyrimidine chemical structure, C21H18Cl2N6, CAS 393846-09-8
4-[4-(3,4-Dichlorophenyl)piperazinyl]-1-phenylpyrazolo[5,4-d]pyrimidine
CAS 393846-09-8C21H18Cl2N6
4-[4-(2-Fluorophenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine chemical structure, C21H19FN6, CAS 393845-77-7
4-[4-(2-Fluorophenyl)piperazin-1-yl]-1-phenylpyrazolo[3,4-d]pyrimidine
CAS 393845-77-7C21H19FN6
1-(4-Chlorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C22H21ClN6O, CAS 393845-93-7
1-(4-Chlorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-93-7C22H21ClN6O
4-[4-(3-Chlorophenyl)piperazin-1-yl]-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C22H21ClN6O, CAS 393845-74-4
4-[4-(3-Chlorophenyl)piperazin-1-yl]-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS 393845-74-4C22H21ClN6O
1-(2,4-Dimethylphenyl)-4-[4-(3-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine chemical structure, C24H26N6O, CAS 393846-01-0
1-(2,4-Dimethylphenyl)-4-[4-(3-methoxyphenyl)piperazin-1-yl]pyrazolo[3,4-d]pyrimidine
CAS 393846-01-0C24H26N6O
4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C22H22N6O, CAS 393846-02-1
4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine
CAS 393846-02-1C22H22N6O