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Murcko scaffold

N-((Thiophen-2-yl)methyl)-2,3-dihydro-1,4-benzodioxin-6-amine scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
7
With full pages
3
Scaffold SMILES

c1csc(CNc2ccc3c(c2)OCCO3)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-((Thiophen-2-yl)methyl)-2,3-dihydro-1,4-benzodioxin-6-amine page
Murcko scaffold c1csc(CNc2ccc3c(c2)OCCO3)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-[(5-Methylthiophen-2-yl)methyl]-2,3-dihydro-1,4-benzodioxin-6-amine chemical structure, C14H15NO2S, CAS 861224-74-0
N-[(5-Methylthiophen-2-yl)methyl]-2,3-dihydro-1,4-benzodioxin-6-amine
CAS 861224-74-0C14H15NO2S
N-((Thiophen-2-yl)methyl)-2,3-dihydro-1,4-benzodioxin-6-amine chemical structure, C13H13NO2S, CAS 869950-48-1
N-((Thiophen-2-yl)methyl)-2,3-dihydro-1,4-benzodioxin-6-amine
CAS 869950-48-1C13H13NO2S
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C15H14ClNO3S, CAS 851722-04-8
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-(thiophen-2-ylmethyl)acetamide
CAS 851722-04-8C15H14ClNO3S
N-[(3-Methylthiophen-2-yl)methyl]-2,3-dihydro-1,4-benzodioxin-6-amine chemical structure, C14H15NO2S, CAS 861224-75-1
N-[(3-Methylthiophen-2-yl)methyl]-2,3-dihydro-1,4-benzodioxin-6-amine
CAS 861224-75-1C14H15NO2S
N-(Thien-2-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-amine hydrochloride chemical structure, C13H14ClNO2S, CAS 1049733-16-5
N-(Thien-2-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-amine hydrochloride
CAS 1049733-16-5C13H14ClNO2S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-[(thiophen-2-yl)methyl]prop-2-enamide chemical structure, C16H15NO3S, CAS 2094359-65-4
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-[(thiophen-2-yl)methyl]prop-2-enamide
CAS 2094359-65-4C16H15NO3S
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-[(5-methylthiophen-2-yl)methyl]prop-2-enamide chemical structure, C17H17NO3S, CAS 2094285-35-3
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N-[(5-methylthiophen-2-yl)methyl]prop-2-enamide
CAS 2094285-35-3C17H17NO3S