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Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
1
Scaffold SMILES

c1ccc(-c2ccccc2C2=NCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccccc2C2=NCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-([1,1'-Biphenyl]-2-yl)-4,4-dimethyl-4,5-dihydrooxazole chemical structure, C17H17NO, CAS 57598-40-0
2-([1,1'-Biphenyl]-2-yl)-4,4-dimethyl-4,5-dihydrooxazole
CAS 57598-40-0C17H17NO
4,4-Dimethyl-2-(4'-methyl-2-biphenylyl)-2-oxazoline chemical structure, C18H19NO, CAS 84392-32-5
4,4-Dimethyl-2-(4'-methyl-2-biphenylyl)-2-oxazoline
CAS 84392-32-5C18H19NO
4,5-Dihydro-2-(4'-methoxy(1,1'-biphenyl)-2-yl)-4,4-dimethyloxazole chemical structure, C18H19NO2, CAS 84392-30-3
4,5-Dihydro-2-(4'-methoxy(1,1'-biphenyl)-2-yl)-4,4-dimethyloxazole
CAS 84392-30-3C18H19NO2
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2'-methyl[1,1'-biphenyl]-2-yl)- chemical structure, C18H19NO, CAS 156641-63-3
Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2'-methyl[1,1'-biphenyl]-2-yl)-
CAS 156641-63-3C18H19NO
4,4-Dimethyl-2-(4'-methoxymethoxymethylbiphenyl-2-yl)oxazoline chemical structure, C20H23NO3, CAS 158144-37-7
4,4-Dimethyl-2-(4'-methoxymethoxymethylbiphenyl-2-yl)oxazoline
CAS 158144-37-7C20H23NO3
4,5-Dihydro-2-(6-methoxy(1,1'-biphenyl)-2-yl)-4,4-dimethyloxazole chemical structure, C18H19NO2, CAS 57598-35-3
4,5-Dihydro-2-(6-methoxy(1,1'-biphenyl)-2-yl)-4,4-dimethyloxazole
CAS 57598-35-3C18H19NO2
2-(2'-Ethyl[1,1'-biphenyl]-2-yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole chemical structure, C19H21NO, CAS 89393-46-4
2-(2'-Ethyl[1,1'-biphenyl]-2-yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
CAS 89393-46-4C19H21NO
2-[2,3,5-Trifluoro-6-(4-methoxyphenyl)phenyl]-4,5-dihydro-1,3-oxazole chemical structure, C16H12F3NO2, CAS 1357478-01-3
2-[2,3,5-Trifluoro-6-(4-methoxyphenyl)phenyl]-4,5-dihydro-1,3-oxazole
CAS 1357478-01-3C16H12F3NO2
2-(5-Bromo-2a(2),6a(2)-dimethoxy-4a(2)-pentyl[1,1a(2)-biphenyl]-2-yl)-4,5-dihydro-4,4-dimethyloxazole chemical structure, C24H30BrNO3, CAS 89368-13-8
2-(5-Bromo-2a(2),6a(2)-dimethoxy-4a(2)-pentyl[1,1a(2)-biphenyl]-2-yl)-4,5-dihydro-4,4-dimethyloxazole
CAS 89368-13-8C24H30BrNO3
2-(4,4-Dimethyl-5H-1,3-oxazol-2-yl)-3-phenylbenzaldehyde chemical structure, C18H17NO2, CAS 78265-08-4
2-(4,4-Dimethyl-5H-1,3-oxazol-2-yl)-3-phenylbenzaldehyde
CAS 78265-08-4C18H17NO2