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Murcko scaffold

5-Biphenyl-2-yl-1H-tetrazole scaffold

73 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
73
With full pages
18
Scaffold SMILES

c1ccc(-c2ccccc2-c2nn[nH]n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Biphenyl-2-yl-1H-tetrazole page
Murcko scaffold c1ccc(-c2ccccc2-c2nn[nH]n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 73 chemicals

N-(1-Oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)valine chemical structure, C24H29N5O3, CAS 943333-68-4
N-(1-Oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)valine
CAS 943333-68-4C24H29N5O3
Valsartan chemical structure, C24H29N5O3, CAS 137862-53-4
Valsartan
CAS 137862-53-4C24H29N5O3
Valsartan, D- chemical structure, C24H29N5O3, CAS 137862-87-4
Valsartan, D-
CAS 137862-87-4C24H29N5O3
5-(4'-Methyl-1,1'-biphenyl-2-yl)-1H-tetrazole chemical structure, C14H12N4, CAS 120568-11-8
5-(4'-Methyl-1,1'-biphenyl-2-yl)-1H-tetrazole
CAS 120568-11-8C14H12N4
Hydrochlorothiazide, valsartan chemical structure, C31H37ClN8O7S2, CAS 186615-83-8
Hydrochlorothiazide, valsartan
CAS 186615-83-8C31H37ClN8O7S2
5-(4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl)-2H-tetrazole chemical structure, C14H11BrN4, CAS 138402-33-2
5-(4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl)-2H-tetrazole
CAS 138402-33-2C14H11BrN4
N-(2-Methoxyethyl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-amine chemical structure, C22H27N5O2, CAS 137862-88-5
N-(2-Methoxyethyl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-amine
CAS 137862-88-5C22H27N5O2
4-Hydroxyvalsartan chemical structure, C24H29N5O4, CAS 188259-69-0
4-Hydroxyvalsartan
CAS 188259-69-0C24H29N5O4
N-((2'-(2H-Tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-L-valine chemical structure, C19H21N5O2, CAS 676129-92-3
N-((2'-(2H-Tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-L-valine
CAS 676129-92-3C19H21N5O2
Amlodipine mixture with valsartan chemical structure, C44H54ClN7O8, CAS 254972-16-2
Amlodipine mixture with valsartan
CAS 254972-16-2C44H54ClN7O8
(2'-(1H-Tetrazol-5-yl)biphenyl-4-yl)methanol chemical structure, C14H12N4O, CAS 160514-13-6
(2'-(1H-Tetrazol-5-yl)biphenyl-4-yl)methanol
CAS 160514-13-6C14H12N4O
N-(1-Oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-L-valine methyl ester chemical structure, C25H31N5O3, CAS 137863-17-3
N-(1-Oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-L-valine methyl ester
CAS 137863-17-3C25H31N5O3
2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity) chemical structure, C14H10N4O, CAS 151052-40-3
2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity)
CAS 151052-40-3C14H10N4O
L-Valine, N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methylene]-(9CI) chemical structure, C19H19N5O2, CAS 676129-91-2
L-Valine, N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methylene]-(9CI)
CAS 676129-91-2C19H19N5O2
5-Biphenyl-2-yl-1H-tetrazole chemical structure, C13H10N4, CAS 147330-32-3
5-Biphenyl-2-yl-1H-tetrazole
CAS 147330-32-3C13H10N4
5-[4'-(Bromomethyl)[1,1'-biphenyl]-2-yl]-1-tert-butyl-1H-tetrazole chemical structure, C18H19BrN4, CAS 150766-87-3
5-[4'-(Bromomethyl)[1,1'-biphenyl]-2-yl]-1-tert-butyl-1H-tetrazole
CAS 150766-87-3C18H19BrN4
N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]amine chemical structure, C14H13N5, CAS 147225-68-1
N-[[2'-(1H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]amine
CAS 147225-68-1C14H13N5
Exforge chemical structure, C50H60ClN7O11S, CAS 1190398-97-0
Exforge
CAS 1190398-97-0C50H60ClN7O11S
Valsartan acid chemical structure, C14H10N4O2, CAS 164265-78-5
Valsartan acid
CAS 164265-78-5C14H10N4O2
(4-(2-(1H-1,2,3,4-Tetrazol-5-yl)phenyl)phenyl)methanamine hydrochloride chemical structure, C14H14ClN5, CAS 145733-69-3
(4-(2-(1H-1,2,3,4-Tetrazol-5-yl)phenyl)phenyl)methanamine hydrochloride
CAS 145733-69-3C14H14ClN5
N-(2-Hydroxyethyl)-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}pentanamide chemical structure, C21H25N5O2, CAS 137862-58-9
N-(2-Hydroxyethyl)-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}pentanamide
CAS 137862-58-9C21H25N5O2
N-Butanoyl-2-methyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}alanine chemical structure, C22H25N5O3, CAS 137863-21-9
N-Butanoyl-2-methyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}alanine
CAS 137863-21-9C22H25N5O3
5-(4'-(Chloromethyl)-[1,1'-biphenyl]-2-yl)-2H-tetrazole chemical structure, C14H11ClN4, CAS 161952-66-5
5-(4'-(Chloromethyl)-[1,1'-biphenyl]-2-yl)-2H-tetrazole
CAS 161952-66-5C14H11ClN4
5-(4'-(Dibromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole chemical structure, C14H10Br2N4, CAS 1127249-17-5
5-(4'-(Dibromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole
CAS 1127249-17-5C14H10Br2N4