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Murcko scaffold

Ring system with 2 rings and 13 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
8
With full pages
0
Scaffold SMILES

O=C1CCC(c2cncnc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC(c2cncnc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-(2-Ethoxy-5-pyrimidinyl)-4-hydroxycyclohexanone chemical structure, C12H16N2O3, CAS 708274-31-1
4-(2-Ethoxy-5-pyrimidinyl)-4-hydroxycyclohexanone
CAS 708274-31-1C12H16N2O3
4-Hydroxy-4-(5-pyrimidinyl)cyclohexanone chemical structure, C10H12N2O2, CAS 708274-26-4
4-Hydroxy-4-(5-pyrimidinyl)cyclohexanone
CAS 708274-26-4C10H12N2O2
1-(2-Methylpyrimidin-5-yl)-4-oxocyclohexanecarbonitrile chemical structure, C12H13N3O, CAS 1600498-54-1
1-(2-Methylpyrimidin-5-yl)-4-oxocyclohexanecarbonitrile
CAS 1600498-54-1C12H13N3O
4-Oxo-1-(pyrimidin-5-yl)cyclohexane-1-carbonitrile chemical structure, C11H11N3O, CAS 1600498-55-2
4-Oxo-1-(pyrimidin-5-yl)cyclohexane-1-carbonitrile
CAS 1600498-55-2C11H11N3O
4-(2-Methoxy-5-pyrimidinyl)cyclohexanone chemical structure, C11H14N2O2, CAS 1417609-20-1
4-(2-Methoxy-5-pyrimidinyl)cyclohexanone
CAS 1417609-20-1C11H14N2O2
1-(4-Methylpyrimidin-5-yl)-4-oxocyclohexane-1-carboxylic acid chemical structure, C12H14N2O3, CAS 2229439-92-1
1-(4-Methylpyrimidin-5-yl)-4-oxocyclohexane-1-carboxylic acid
CAS 2229439-92-1C12H14N2O3
4-Oxo-1-(pyrimidin-5-yl)cyclohexane-1-carboxylic acid chemical structure, C11H12N2O3, CAS 2228616-15-5
4-Oxo-1-(pyrimidin-5-yl)cyclohexane-1-carboxylic acid
CAS 2228616-15-5C11H12N2O3
1-(2-{[(tert-Butoxy)carbonyl]amino}pyrimidin-5-yl)-4-oxocyclohexane-1-carboxylic acid chemical structure, C16H21N3O5, CAS 2228181-29-9
1-(2-{[(tert-Butoxy)carbonyl]amino}pyrimidin-5-yl)-4-oxocyclohexane-1-carboxylic acid
CAS 2228181-29-9C16H21N3O5