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Murcko scaffold

1-(2-Pyridyl)piperazine scaffold

1,855 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 12
Chemicals: 1,855
With full pages: 112

Scaffold SMILES

c1ccc(N2CCNCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-(2-Pyridyl)piperazine page

Murcko scaffold c1ccc(N2CCNCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,855 chemicals

1-(2-Pyridyl)piperazine chemical structure, C9H13N3, CAS 34803-66-2

1-(2-Pyridyl)piperazine

CAS 34803-66-2C₉H₁₃N₃

1-(3-Fluoro-2-pyridinyl)piperazine chemical structure, C9H12FN3, CAS 85386-84-1

1-(3-Fluoro-2-pyridinyl)piperazine

CAS 85386-84-1C₉H₁₂FN₃

2-(4-Methylpiperazin-1-yl)pyridin-3-amine chemical structure, C10H16N4, CAS 5028-17-1

2-(4-Methylpiperazin-1-yl)pyridin-3-amine

CAS 5028-17-1C₁₀H₁₆N₄

3-Pyridinesulfonamide, 6-(4-methyl-1-piperazinyl)- chemical structure, C10H16N4O2S, CAS 38029-90-2

3-Pyridinesulfonamide, 6-(4-methyl-1-piperazinyl)-

CAS 38029-90-2C₁₀H₁₆N₄O₂S

3-Pyridinesulfonamide, N-methyl-6-(4-methyl-1-piperazinyl)- chemical structure, C11H18N4O2S, CAS 38029-91-3

3-Pyridinesulfonamide, N-methyl-6-(4-methyl-1-piperazinyl)-

CAS 38029-91-3C₁₁H₁₈N₄O₂S

3-Pyridinesulfonamide, N,N-dimethyl-6-(4-methyl-1-piperazinyl)- chemical structure, C12H20N4O2S, CAS 38029-92-4

3-Pyridinesulfonamide, N,N-dimethyl-6-(4-methyl-1-piperazinyl)-

CAS 38029-92-4C₁₂H₂₀N₄O₂S

3-Pyridinesulfonamide, N-ethyl-6-(4-methyl-1-piperazinyl)- chemical structure, C12H20N4O2S, CAS 38029-93-5

3-Pyridinesulfonamide, N-ethyl-6-(4-methyl-1-piperazinyl)-

CAS 38029-93-5C₁₂H₂₀N₄O₂S

3-Pyridinesulfonamide, N,N-diethyl-6-(4-methyl-1-piperazinyl)- chemical structure, C14H24N4O2S, CAS 38029-94-6

3-Pyridinesulfonamide, N,N-diethyl-6-(4-methyl-1-piperazinyl)-

CAS 38029-94-6C₁₄H₂₄N₄O₂S

2-(4-Methylpiperazin-1-yl)nicotinic acid chemical structure, C11H15N3O2, CAS 38029-97-9

2-(4-Methylpiperazin-1-yl)nicotinic acid

CAS 38029-97-9C₁₁H₁₅N₃O₂

3-Pyridinesulfonic acid, 6-(4-methyl-1-piperazinyl)- chemical structure, C10H15N3O3S, CAS 38030-00-1

3-Pyridinesulfonic acid, 6-(4-methyl-1-piperazinyl)-

CAS 38030-00-1C₁₀H₁₅N₃O₃S

3-Pyridinecarboxamide, N,N-diethyl-6-(4-methyl-1-piperazinyl)- chemical structure, C15H24N4O, CAS 38030-01-2

3-Pyridinecarboxamide, N,N-diethyl-6-(4-methyl-1-piperazinyl)-

CAS 38030-01-2C₁₅H₂₄N₄O

3-Pyridinesulfonamide, 2-(4-methyl-1-piperazinyl)- chemical structure, C10H16N4O2S, CAS 38030-49-8

3-Pyridinesulfonamide, 2-(4-methyl-1-piperazinyl)-

CAS 38030-49-8C₁₀H₁₆N₄O₂S

N-Methyl-2-(4-methyl-1-piperazinyl)-3-pyridinesulfonamide chemical structure, C11H18N4O2S, CAS 38030-50-1

N-Methyl-2-(4-methyl-1-piperazinyl)-3-pyridinesulfonamide

CAS 38030-50-1C₁₁H₁₈N₄O₂S

3-Pyridinesulfonamide, N,N-dimethyl-2-(4-methyl-1-piperazinyl)- chemical structure, C12H20N4O2S, CAS 38030-52-3

3-Pyridinesulfonamide, N,N-dimethyl-2-(4-methyl-1-piperazinyl)-

CAS 38030-52-3C₁₂H₂₀N₄O₂S

N-Ethyl-2-(4-methyl-1-piperazinyl)-3-pyridinesulfonamide chemical structure, C12H20N4O2S, CAS 38030-54-5

N-Ethyl-2-(4-methyl-1-piperazinyl)-3-pyridinesulfonamide

CAS 38030-54-5C₁₂H₂₀N₄O₂S

(4-(2-Pyridinyl)-1-piperazinyl)methylenecyanamide chemical structure, C11H13N5, CAS 70486-26-9

(4-(2-Pyridinyl)-1-piperazinyl)methylenecyanamide

CAS 70486-26-9C₁₁H₁₃N₅

1-(Chloroacetyl)-4-pyridin-2-ylpiperazine chemical structure, C11H14ClN3O, CAS 491837-81-1

1-(Chloroacetyl)-4-pyridin-2-ylpiperazine

CAS 491837-81-1C₁₁H₁₄ClN₃O

1-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-one chemical structure, C11H15N3O, CAS 419556-94-8

1-[4-(Pyridin-2-yl)piperazin-1-yl]ethan-1-one

CAS 419556-94-8C₁₁H₁₅N₃O

1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine chemical structure, C10H12F3N3, CAS 132834-58-3

1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine

CAS 132834-58-3C₁₀H₁₂F₃N₃

1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine chemical structure, C10H11ClF3N3, CAS 132834-59-4

1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine

CAS 132834-59-4C₁₀H₁₁ClF₃N₃

2-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]piperazino}ethan-1-ol chemical structure, C12H15ClF3N3O, CAS 215434-40-5

2-{4-[3-Chloro-5-(trifluoromethyl)-2-pyridyl]piperazino}ethan-1-ol

CAS 215434-40-5C₁₂H₁₅ClF₃N₃O

1-Ethyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine chemical structure, C12H16F3N3, CAS 308294-34-0

1-Ethyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine

CAS 308294-34-0C₁₂H₁₆F₃N₃

4-Oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butanoic acid chemical structure, C13H17N3O3, CAS 213186-59-5

4-Oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butanoic acid

CAS 213186-59-5C₁₃H₁₇N₃O₃

2-Chloro-1-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethan-1-one chemical structure, C12H12Cl2F3N3O, CAS 260553-15-9

2-Chloro-1-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethan-1-one

CAS 260553-15-9C₁₂H₁₂Cl₂F₃N₃O