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Murcko scaffold

Ring system with 3 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
14
With full pages
4
Scaffold SMILES

O=C1NC(=NN=Cc2ccco2)SC1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=NN=Cc2ccco2)SC1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-Furaldehyde ((2E)-3-allyl-5-(2,5-dichlorobenzyl)-4-oxo-1,3-thiazolidin-2-ylidene)hydrazone chemical structure, C18H15Cl2N3O2S, CAS 292056-94-1
2-Furaldehyde ((2E)-3-allyl-5-(2,5-dichlorobenzyl)-4-oxo-1,3-thiazolidin-2-ylidene)hydrazone
CAS 292056-94-1C18H15Cl2N3O2S
(Z)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(2-methylbenzyl)thiazolidin-4-one chemical structure, C16H15N3O2S, CAS 292051-97-9
(Z)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(2-methylbenzyl)thiazolidin-4-one
CAS 292051-97-9C16H15N3O2S
2-(Furan-2-ylmethylene-hydrazono)-5-(3-methyl-benzyl)-thiazolidin-4-one chemical structure, C16H15N3O2S, CAS 215933-09-8
2-(Furan-2-ylmethylene-hydrazono)-5-(3-methyl-benzyl)-thiazolidin-4-one
CAS 215933-09-8C16H15N3O2S
(Z)-5-(4-Fluorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C15H12FN3O2S, CAS 1321804-91-4
(Z)-5-(4-Fluorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 1321804-91-4C15H12FN3O2S
(2E)-5-(2,5-Dichlorobenzyl)-2-[(2E)-(furan-2-ylmethylidene)hydrazinylidene]-1,3-thiazolidin-4-one chemical structure, C15H11Cl2N3O2S, CAS 5854-73-9
(2E)-5-(2,5-Dichlorobenzyl)-2-[(2E)-(furan-2-ylmethylidene)hydrazinylidene]-1,3-thiazolidin-4-one
CAS 5854-73-9C15H11Cl2N3O2S
5-(4-Chloro-benzyl)-2-(furan-2-ylmethylene-hydrazono)-thiazolidin-4-one chemical structure, C15H12ClN3O2S, CAS 306321-30-2
5-(4-Chloro-benzyl)-2-(furan-2-ylmethylene-hydrazono)-thiazolidin-4-one
CAS 306321-30-2C15H12ClN3O2S
(E)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(4-methylbenzyl)thiazolidin-4-one chemical structure, C16H15N3O2S, CAS 306321-29-9
(E)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(4-methylbenzyl)thiazolidin-4-one
CAS 306321-29-9C16H15N3O2S
(E)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(4-methoxybenzyl)thiazolidin-4-one chemical structure, C16H15N3O3S, CAS 303792-14-5
(E)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(4-methoxybenzyl)thiazolidin-4-one
CAS 303792-14-5C16H15N3O3S
(E)-5-Benzyl-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C15H13N3O2S, CAS 303793-76-2
(E)-5-Benzyl-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 303793-76-2C15H13N3O2S
(Z)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(3-methoxybenzyl)thiazolidin-4-one chemical structure, C16H15N3O3S, CAS 620541-60-8
(Z)-2-((E)-(Furan-2-ylmethylene)hydrazono)-5-(3-methoxybenzyl)thiazolidin-4-one
CAS 620541-60-8C16H15N3O3S
(Z)-5-(2,3-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C15H11Cl2N3O2S, CAS 303793-92-2
(Z)-5-(2,3-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 303793-92-2C15H11Cl2N3O2S
(Z)-5-(3,4-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C15H11Cl2N3O2S, CAS 327062-23-7
(Z)-5-(3,4-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 327062-23-7C15H11Cl2N3O2S
(Z)-5-(4-Ethoxybenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C17H17N3O3S, CAS 1322000-57-6
(Z)-5-(4-Ethoxybenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 1322000-57-6C17H17N3O3S
(Z)-5-(2,5-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one chemical structure, C15H11Cl2N3O2S, CAS 1321748-55-3
(Z)-5-(2,5-Dichlorobenzyl)-2-((E)-(furan-2-ylmethylene)hydrazono)thiazolidin-4-one
CAS 1321748-55-3C15H11Cl2N3O2S