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Murcko scaffold

Ring system with 3 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
7
With full pages
1
Scaffold SMILES

O=C1NC(=Nc2ccccc2)SC1=CC=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=Nc2ccccc2)SC1=CC=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

2-(3-Chlorophenylamino)-5-(3-(furan-2-yl)allylidene)thiazol-4(5H)-one chemical structure, C16H11ClN2O2S, CAS 850737-64-3
2-(3-Chlorophenylamino)-5-(3-(furan-2-yl)allylidene)thiazol-4(5H)-one
CAS 850737-64-3C16H11ClN2O2S
(2Z,5E)-5-((E)-3-(Furan-2-yl)allylidene)-2-(phenylimino)thiazolidin-4-one chemical structure, C16H12N2O2S, CAS 714255-73-9
(2Z,5E)-5-((E)-3-(Furan-2-yl)allylidene)-2-(phenylimino)thiazolidin-4-one
CAS 714255-73-9C16H12N2O2S
(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-2-(3-methylanilino)-1,3-thiazol-4-one chemical structure, C17H14N2O2S, CAS 1164554-71-5
(5Z)-5-[(E)-3-(Furan-2-yl)prop-2-enylidene]-2-(3-methylanilino)-1,3-thiazol-4-one
CAS 1164554-71-5C17H14N2O2S
(2Z,5E)-2-((2-Chlorophenyl)imino)-5-((E)-3-(furan-2-yl)allylidene)thiazolidin-4-one chemical structure, C16H11ClN2O2S, CAS 861644-28-2
(2Z,5E)-2-((2-Chlorophenyl)imino)-5-((E)-3-(furan-2-yl)allylidene)thiazolidin-4-one
CAS 861644-28-2C16H11ClN2O2S
2-(3-Bromophenylamino)-5-(3-(furan-2-yl)allylidene)thiazol-4(5H)-one chemical structure, C16H11BrN2O2S, CAS 849025-32-7
2-(3-Bromophenylamino)-5-(3-(furan-2-yl)allylidene)thiazol-4(5H)-one
CAS 849025-32-7C16H11BrN2O2S
(2Z,5E)-5-((E)-3-(Furan-2-yl)allylidene)-2-((4-hydroxyphenyl)imino)thiazolidin-4-one chemical structure, C16H12N2O3S, CAS 862194-16-9
(2Z,5E)-5-((E)-3-(Furan-2-yl)allylidene)-2-((4-hydroxyphenyl)imino)thiazolidin-4-one
CAS 862194-16-9C16H12N2O3S
(2Z,5E)-2-((2,4-Dimethylphenyl)imino)-5-((E)-3-(furan-2-yl)allylidene)thiazolidin-4-one chemical structure, C18H16N2O2S, CAS 850764-76-0
(2Z,5E)-2-((2,4-Dimethylphenyl)imino)-5-((E)-3-(furan-2-yl)allylidene)thiazolidin-4-one
CAS 850764-76-0C18H16N2O2S