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Murcko scaffold

Ring system with 4 rings and 22 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
6
With full pages
4
Scaffold SMILES

O=C1Nc2cc(-c3ccccc3)ccc2C1=Cc1ccc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2cc(-c3ccccc3)ccc2C1=Cc1ccc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

3-[2,4-Dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid chemical structure, C24H22N2O3, CAS 251356-45-3
3-[2,4-Dimethyl-5-[(Z)-(2-oxo-6-phenyl-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
CAS 251356-45-3C24H22N2O3
RefChem:854780 chemical structure, C26H26N2O5, CAS 949164-80-1
RefChem:854780
CAS 949164-80-1C26H26N2O5
3-[4-Methyl-5-(2-oxo-6-phenyl-1,2-dihydro-indol3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid chemical structure, C23H20N2O3, CAS 251356-46-4
3-[4-Methyl-5-(2-oxo-6-phenyl-1,2-dihydro-indol3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid
CAS 251356-46-4C23H20N2O3
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 chemical structure, C26H26N2O5
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603
C26H26N2O5
3-[2-[[6-(3-Methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-5-methyl-1H-pyrrol-3-yl]propanoic acid chemical structure, C24H22N2O4, CAS 748153-84-6
3-[2-[[6-(3-Methoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl]-5-methyl-1H-pyrrol-3-yl]propanoic acid
CAS 748153-84-6C24H22N2O4
3-(5-{(E)-[6-(3,5-Dimethoxyphenyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid chemical structure, C26H26N2O5
3-(5-{(E)-[6-(3,5-Dimethoxyphenyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
C26H26N2O5