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Murcko scaffold

Ring system with 4 rings and 22 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
4
With full pages
3
Scaffold SMILES

O=C(c1cccs1)c1ccc2cc(-c3ccccc3)ncn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cccs1)c1ccc2cc(-c3ccccc3)ncn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

ET 3-(3-CL-Phenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C21H15ClN2O3S, CAS 302913-14-0
ET 3-(3-CL-Phenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-14-0C21H15ClN2O3S
ET 3-(4-Bromophenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C21H15BrN2O3S, CAS 302913-18-4
ET 3-(4-Bromophenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-18-4C21H15BrN2O3S
ET 3-(4-CL-Phenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C21H15ClN2O3S, CAS 302913-16-2
ET 3-(4-CL-Phenyl)-7-(2-thienylcarbonyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-16-2C21H15ClN2O3S
1-[3-Phenyl-7-(thiophene-2-carbonyl)pyrrolo[1,2-c]pyrimidin-5-yl]ethan-1-one chemical structure, C20H14N2O2S, CAS 646062-71-7
1-[3-Phenyl-7-(thiophene-2-carbonyl)pyrrolo[1,2-c]pyrimidin-5-yl]ethan-1-one
CAS 646062-71-7C20H14N2O2S