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Murcko scaffold

Ring system with 3 rings and 25 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
18
With full pages
16
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccccc1C(=O)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccccc1C(=O)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

2-(3-Methylphenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]acetamide chemical structure, C20H22N2O4, CAS 428823-32-9
2-(3-Methylphenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]acetamide
CAS 428823-32-9C20H22N2O4
2-(3-Methylphenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]butanamide chemical structure, C22H26N2O4, CAS 876047-42-6
2-(3-Methylphenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]butanamide
CAS 876047-42-6C22H26N2O4
N-[2-(4-Morpholinylcarbonyl)phenyl]-2-phenoxybutanamide chemical structure, C21H24N2O4, CAS 876115-21-8
N-[2-(4-Morpholinylcarbonyl)phenyl]-2-phenoxybutanamide
CAS 876115-21-8C21H24N2O4
2-(2-Chlorophenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]propanamide chemical structure, C20H21ClN2O4, CAS 876121-68-5
2-(2-Chlorophenoxy)-N-[2-(morpholine-4-carbonyl)phenyl]propanamide
CAS 876121-68-5C20H21ClN2O4
2-(2-Isopropylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C22H26N2O4, CAS 875010-88-1
2-(2-Isopropylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875010-88-1C22H26N2O4
2-(3,5-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C21H24N2O4, CAS 875010-90-5
2-(3,5-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875010-90-5C21H24N2O4
2-(2,6-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C21H24N2O4, CAS 875010-91-6
2-(2,6-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875010-91-6C21H24N2O4
2-(4-Isopropylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C22H26N2O4, CAS 875010-92-7
2-(4-Isopropylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875010-92-7C22H26N2O4
2-(4-Chloro-2-methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C20H21ClN2O4, CAS 875011-08-8
2-(4-Chloro-2-methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875011-08-8C20H21ClN2O4
2-(4-Bromophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C19H19BrN2O4, CAS 875011-19-1
2-(4-Bromophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875011-19-1C19H19BrN2O4
2-(2,5-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C21H24N2O4, CAS 875011-26-0
2-(2,5-Dimethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875011-26-0C21H24N2O4
2-(2-Chlorophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide chemical structure, C19H19ClN2O4, CAS 875011-32-8
2-(2-Chlorophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]acetamide
CAS 875011-32-8C19H19ClN2O4
2-(4-Methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide chemical structure, C21H24N2O4, CAS 875011-45-3
2-(4-Methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide
CAS 875011-45-3C21H24N2O4
2-(4-Chlorophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide chemical structure, C20H21ClN2O4, CAS 815625-11-7
2-(4-Chlorophenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide
CAS 815625-11-7C20H21ClN2O4
2-(4-Methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]butanamide chemical structure, C22H26N2O4, CAS 875082-60-3
2-(4-Methylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]butanamide
CAS 875082-60-3C22H26N2O4
2-(4-Ethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide chemical structure, C22H26N2O4, CAS 881573-71-3
2-(4-Ethylphenoxy)-N-[2-(4-morpholinylcarbonyl)phenyl]propanamide
CAS 881573-71-3C22H26N2O4
2-(2-Fluorophenoxy)-N-[2-(morpholin-4-ylcarbonyl)phenyl]butanamide chemical structure, C21H23FN2O4, CAS 905794-75-4
2-(2-Fluorophenoxy)-N-[2-(morpholin-4-ylcarbonyl)phenyl]butanamide
CAS 905794-75-4C21H23FN2O4
2-(4-Chlorophenoxy)-N-[2-(morpholin-4-ylcarbonyl)phenyl]butanamide chemical structure, C21H23ClN2O4, CAS 914355-88-7
2-(4-Chlorophenoxy)-N-[2-(morpholin-4-ylcarbonyl)phenyl]butanamide
CAS 914355-88-7C21H23ClN2O4