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Murcko scaffold

Ring system with 3 rings and 25 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccccc1C(=O)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccccc1C(=O)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxyacetamide chemical structure, C20H23N3O3, CAS 306752-90-9
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxyacetamide
CAS 306752-90-9C20H23N3O3
2-(4-Chlorophenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide chemical structure, C20H22ClN3O3, CAS 350681-46-8
2-(4-Chlorophenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide
CAS 350681-46-8C20H22ClN3O3
RefChem:381295 chemical structure, C21H24ClN3O3, CAS 6044-99-1
RefChem:381295
CAS 6044-99-1C21H24ClN3O3
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxybutanamide chemical structure, C22H27N3O3, CAS 876115-49-0
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxybutanamide
CAS 876115-49-0C22H27N3O3
2-(2,5-Dimethylphenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide chemical structure, C22H27N3O3, CAS 815623-25-7
2-(2,5-Dimethylphenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide
CAS 815623-25-7C22H27N3O3
2-(2-Chlorophenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide chemical structure, C20H22ClN3O3, CAS 815623-29-1
2-(2-Chlorophenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]acetamide
CAS 815623-29-1C20H22ClN3O3
2-(4-Methylphenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]propanamide chemical structure, C22H27N3O3, CAS 815623-41-7
2-(4-Methylphenoxy)-N-[2-(4-methylpiperazine-1-carbonyl)phenyl]propanamide
CAS 815623-41-7C22H27N3O3
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxypropanamide chemical structure, C21H25N3O3, CAS 815623-48-4
N-[2-(4-Methylpiperazine-1-carbonyl)phenyl]-2-phenoxypropanamide
CAS 815623-48-4C21H25N3O3