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Murcko scaffold

2H,3H-[1,2]Thiazolo[5,4-b]pyridin-3-one scaffold

16 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
16
With full pages
3
Scaffold SMILES

O=c1[nH]sc2ncccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2H,3H-[1,2]Thiazolo[5,4-b]pyridin-3-one page
Murcko scaffold O=c1[nH]sc2ncccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Isothiazolo(5,4-b)pyridin-3(2H)-one, 4,6-dimethyl- chemical structure, C8H8N2OS, CAS 60750-75-6
Isothiazolo(5,4-b)pyridin-3(2H)-one, 4,6-dimethyl-
CAS 60750-75-6C8H8N2OS
Ethyl 2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetate chemical structure, C12H14N2O3S, CAS 97055-45-3
Ethyl 2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetate
CAS 97055-45-3C12H14N2O3S
2H,3H-[1,2]Thiazolo[5,4-b]pyridin-3-one chemical structure, C6H4N2OS, CAS 4337-60-4
2H,3H-[1,2]Thiazolo[5,4-b]pyridin-3-one
CAS 4337-60-4C6H4N2OS
Isothiazolo(5,4-b)pyridin-3(2H)-one, 2-acetyl-4,6-dimethyl- chemical structure, C10H10N2O2S, CAS 97248-88-9
Isothiazolo(5,4-b)pyridin-3(2H)-one, 2-acetyl-4,6-dimethyl-
CAS 97248-88-9C10H10N2O2S
2,4,6-Trimethylisothiazolo[5,4-b]pyridin-3(2H)-one chemical structure, C9H10N2OS, CAS 60750-77-8
2,4,6-Trimethylisothiazolo[5,4-b]pyridin-3(2H)-one
CAS 60750-77-8C9H10N2OS
Isothiazolo(5,4-b)pyridine-2-carboxylic acid, 2,3-dihydro-4,6-dimethyl-3-oxo-, methyl ester chemical structure, C10H10N2O3S, CAS 97248-90-3
Isothiazolo(5,4-b)pyridine-2-carboxylic acid, 2,3-dihydro-4,6-dimethyl-3-oxo-, methyl ester
CAS 97248-90-3C10H10N2O3S
2-Methyl[1,2]thiazolo[5,4-b]pyridin-3(2H)-one chemical structure, C7H6N2OS, CAS 91859-64-2
2-Methyl[1,2]thiazolo[5,4-b]pyridin-3(2H)-one
CAS 91859-64-2C7H6N2OS
2-Ethylisothiazolo[5,4-b]pyridin-3(2H)-one chemical structure, C8H8N2OS, CAS 91859-65-3
2-Ethylisothiazolo[5,4-b]pyridin-3(2H)-one
CAS 91859-65-3C8H8N2OS
2-(Propan-2-yl)[1,2]thiazolo[5,4-b]pyridin-3(2H)-one chemical structure, C9H10N2OS, CAS 91859-63-1
2-(Propan-2-yl)[1,2]thiazolo[5,4-b]pyridin-3(2H)-one
CAS 91859-63-1C9H10N2OS
4,5,6-Trimethyl-2H,3H-[1,2]thiazolo[5,4-b]pyridin-3-one chemical structure, C9H10N2OS, CAS 1374509-73-5
4,5,6-Trimethyl-2H,3H-[1,2]thiazolo[5,4-b]pyridin-3-one
CAS 1374509-73-5C9H10N2OS
N-Methyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide chemical structure, C8H7N3O2S, CAS 89208-06-0
N-Methyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide
CAS 89208-06-0C8H7N3O2S
N-Butyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide chemical structure, C11H13N3O2S, CAS 89208-07-1
N-Butyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide
CAS 89208-07-1C11H13N3O2S
3-Oxo-N-(propan-2-yl)[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide chemical structure, C10H11N3O2S, CAS 89208-08-2
3-Oxo-N-(propan-2-yl)[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide
CAS 89208-08-2C10H11N3O2S
N-Heptyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide chemical structure, C14H19N3O2S, CAS 89208-09-3
N-Heptyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide
CAS 89208-09-3C14H19N3O2S
N-Nonyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide chemical structure, C16H23N3O2S, CAS 89208-10-6
N-Nonyl-3-oxo[1,2]thiazolo[5,4-b]pyridine-2(3H)-carboxamide
CAS 89208-10-6C16H23N3O2S
6-Methoxyisothiazolo[5,4-b]pyridin-3-ol chemical structure, C7H6N2O2S, CAS 2995297-80-6
6-Methoxyisothiazolo[5,4-b]pyridin-3-ol
CAS 2995297-80-6C7H6N2O2S