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Murcko scaffold

Ring system with 3 rings and 23 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
7
With full pages
5
Scaffold SMILES

O=C(COC(=O)c1ccccc1)NCc1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1ccccc1)NCc1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2-hydroxybenzoate chemical structure, C17H15NO6, CAS 380204-51-3
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2-hydroxybenzoate
CAS 380204-51-3C17H15NO6
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2-fluorobenzoate chemical structure, C17H14FNO5, CAS 389812-11-7
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2-fluorobenzoate
CAS 389812-11-7C17H14FNO5
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 4-acetamidobenzoate chemical structure, C19H18N2O6, CAS 389813-13-2
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 4-acetamidobenzoate
CAS 389813-13-2C19H18N2O6
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2,4-difluorobenzoate chemical structure, C17H13F2NO5, CAS 391598-72-4
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2,4-difluorobenzoate
CAS 391598-72-4C17H13F2NO5
2-[(1,3-Benzodioxol-5-ylmethyl)amino]-2-oxoethyl 2,6-dichlorobenzoate chemical structure, C17H13Cl2NO5, CAS 387350-93-8
2-[(1,3-Benzodioxol-5-ylmethyl)amino]-2-oxoethyl 2,6-dichlorobenzoate
CAS 387350-93-8C17H13Cl2NO5
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2,3-dimethylbenzoate chemical structure, C19H19NO5, CAS 391605-73-5
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 2,3-dimethylbenzoate
CAS 391605-73-5C19H19NO5
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 3,4,5-trimethoxybenzoate chemical structure, C20H21NO8, CAS 386262-89-1
[2-(1,3-Benzodioxol-5-ylmethylamino)-2-oxoethyl] 3,4,5-trimethoxybenzoate
CAS 386262-89-1C20H21NO8