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Murcko scaffold

2-(Oxan-4-yl)pyridine scaffold

126 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
126
With full pages
0
Scaffold SMILES

c1ccc(C2CCOCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Oxan-4-yl)pyridine page
Murcko scaffold c1ccc(C2CCOCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 126 chemicals

2-Chloro-4,5-dimethyl-6-(tetrahydro-2H-pyran-4-yl)nicotinonitrile chemical structure, C13H15ClN2O, CAS 1707365-08-9
2-Chloro-4,5-dimethyl-6-(tetrahydro-2H-pyran-4-yl)nicotinonitrile
CAS 1707365-08-9C13H15ClN2O
4-(3-Bromopyridin-2-yl)oxane-4-carboxylic acid chemical structure, C11H12BrNO3, CAS 1877979-92-4
4-(3-Bromopyridin-2-yl)oxane-4-carboxylic acid
CAS 1877979-92-4C11H12BrNO3
4-(6-Bromopyridin-2-yl)oxane-4-carboxylic acid chemical structure, C11H12BrNO3, CAS 2229590-57-0
4-(6-Bromopyridin-2-yl)oxane-4-carboxylic acid
CAS 2229590-57-0C11H12BrNO3
2-Chloro-6-(oxan-4-yl)pyridine-3-carbonitrile chemical structure, C11H11ClN2O, CAS 1890597-89-3
2-Chloro-6-(oxan-4-yl)pyridine-3-carbonitrile
CAS 1890597-89-3C11H11ClN2O
2-Chloro-6-(oxan-4-yl)pyridine-3-carboxylic acid chemical structure, C11H12ClNO3, CAS 1888904-31-1
2-Chloro-6-(oxan-4-yl)pyridine-3-carboxylic acid
CAS 1888904-31-1C11H12ClNO3
4-(Pyridin-2-yl)tetrahydro-2H-pyran-4-amine hydrochloride chemical structure, C10H15ClN2O, CAS 1956380-14-5
4-(Pyridin-2-yl)tetrahydro-2H-pyran-4-amine hydrochloride
CAS 1956380-14-5C10H15ClN2O
[4-(3-Methoxypyridin-2-yl)-tetrahydro-2H-pyran-4-yl]methanamine chemical structure, C12H18N2O2, CAS 1881243-24-8
[4-(3-Methoxypyridin-2-yl)-tetrahydro-2H-pyran-4-yl]methanamine
CAS 1881243-24-8C12H18N2O2
4-(3-Bromopyridin-2-yl)oxan-4-amine chemical structure, C10H13BrN2O, CAS 1863252-35-0
4-(3-Bromopyridin-2-yl)oxan-4-amine
CAS 1863252-35-0C10H13BrN2O
4,5-Dibromo-2-(4-tetrahydropyranyl)pyridine chemical structure, C10H11Br2NO, CAS 1381941-56-5
4,5-Dibromo-2-(4-tetrahydropyranyl)pyridine
CAS 1381941-56-5C10H11Br2NO
5-Bromo-2-(oxan-4-yl)pyridin-4-amine chemical structure, C10H13BrN2O, CAS 1381936-22-6
5-Bromo-2-(oxan-4-yl)pyridin-4-amine
CAS 1381936-22-6C10H13BrN2O
3-Bromo-2-(oxan-4-yl)pyridin-4-amine chemical structure, C10H13BrN2O, CAS 1381941-34-9
3-Bromo-2-(oxan-4-yl)pyridin-4-amine
CAS 1381941-34-9C10H13BrN2O
4-Bromo-3-amino-6-(4-tetrahydropyranyl)pyridine chemical structure, C10H13BrN2O, CAS 1381942-62-6
4-Bromo-3-amino-6-(4-tetrahydropyranyl)pyridine
CAS 1381942-62-6C10H13BrN2O
4-Bromo-5-methyl-2-(4-tetrahydropyranyl)pyridine chemical structure, C11H14BrNO, CAS 1374665-98-1
4-Bromo-5-methyl-2-(4-tetrahydropyranyl)pyridine
CAS 1374665-98-1C11H14BrNO
3,5-Dibromo-6-(4-tetrahydropyranyl)pyridine chemical structure, C10H11Br2NO, CAS 1399482-16-6
3,5-Dibromo-6-(4-tetrahydropyranyl)pyridine
CAS 1399482-16-6C10H11Br2NO
3-Bromo-4-chloro-6-(4-tetrahydropyranyl)pyridine chemical structure, C10H11BrClNO, CAS 1399480-65-9
3-Bromo-4-chloro-6-(4-tetrahydropyranyl)pyridine
CAS 1399480-65-9C10H11BrClNO
3-Bromo-2-(oxan-4-yl)pyridine chemical structure, C10H12BrNO, CAS 1417519-31-3
3-Bromo-2-(oxan-4-yl)pyridine
CAS 1417519-31-3C10H12BrNO
3-Amino-2-(4-tetrahydropyranyl)pyridine chemical structure, C10H14N2O, CAS 1417518-40-1
3-Amino-2-(4-tetrahydropyranyl)pyridine
CAS 1417518-40-1C10H14N2O
4-Chloro-2-(4-tetrahydropyranyl)pyridine chemical structure, C10H12ClNO, CAS 1434127-66-8
4-Chloro-2-(4-tetrahydropyranyl)pyridine
CAS 1434127-66-8C10H12ClNO
4-Amino-3,5-dibromo-2-(4-tetrahydropyranyl)pyridine chemical structure, C10H12Br2N2O, CAS 1563534-65-5
4-Amino-3,5-dibromo-2-(4-tetrahydropyranyl)pyridine
CAS 1563534-65-5C10H12Br2N2O
2-Fluoro-6-(oxan-4-yl)pyridine chemical structure, C10H12FNO, CAS 1563532-04-6
2-Fluoro-6-(oxan-4-yl)pyridine
CAS 1563532-04-6C10H12FNO
4-Fluoro-2-(oxan-4-yl)pyridine chemical structure, C10H12FNO, CAS 1563528-54-0
4-Fluoro-2-(oxan-4-yl)pyridine
CAS 1563528-54-0C10H12FNO
4-Bromo-2-fluoro-6-(oxan-4-yl)pyridine chemical structure, C10H11BrFNO, CAS 1622843-20-2
4-Bromo-2-fluoro-6-(oxan-4-yl)pyridine
CAS 1622843-20-2C10H11BrFNO
4-Bromo-2-methyl-6-(oxan-4-yl)pyridine chemical structure, C11H14BrNO, CAS 1622842-66-3
4-Bromo-2-methyl-6-(oxan-4-yl)pyridine
CAS 1622842-66-3C11H14BrNO
3-Bromo-2-fluoro-6-(oxan-4-yl)pyridine chemical structure, C10H11BrFNO, CAS 1622843-18-8
3-Bromo-2-fluoro-6-(oxan-4-yl)pyridine
CAS 1622843-18-8C10H11BrFNO