Murcko scaffold
2-Oxabicyclo(3.1.0)hexane scaffold
29 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 6
- Chemicals
- 29
- With full pages
- 5
Scaffold SMILES
C1CC2CC2O1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 29 of 29 chemicals
2-Oxa-4-aminobicyclo(3.1.0)hexane-4,6-dicarboxylic acid
CAS 1378838-68-6C7H9NO5
(1R,4R,5S,6R)-4-Amino-2-oxabicyclo(3.1.0)hexane-4,6-dicarboxylic acid
CAS 191471-52-0C7H9NO5
![Ethyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate chemical structure, C8H12O3, CAS 90482-42-1](/s/WPWZXGZTADPNQW-UHFFFAOYSA-N.svg)
Ethyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate
CAS 90482-42-1C8H12O3
![Ethyl (1S,5S,6S)-2-oxabicyclo[3.1.0]Hexane-6-carboxylate chemical structure, C8H12O3, CAS 213137-33-8](/s/WPWZXGZTADPNQW-ACZMJKKPSA-N.svg)
Ethyl (1S,5S,6S)-2-oxabicyclo[3.1.0]Hexane-6-carboxylate
CAS 213137-33-8C8H12O3
![6,6-Dichloro-2-oxabicyclo[3.1.0]hexane chemical structure, C5H6Cl2O, CAS 24765-58-0](/s/BPNWKQDJAQRDPI-UHFFFAOYSA-N.svg)
6,6-Dichloro-2-oxabicyclo[3.1.0]hexane
CAS 24765-58-0C5H6Cl2O
![Methyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate chemical structure, C7H10O3, CAS 89921-52-8](/s/GXZWDGVVQCYWMR-UHFFFAOYSA-N.svg)
Methyl 2-oxabicyclo[3.1.0]hexane-6-carboxylate
CAS 89921-52-8C7H10O3
![(1S,4S,5R,6S)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid chemical structure, C7H9NO5, CAS 191471-51-9](/s/YASVRZWVUGJELU-ADXDAQDCSA-N.svg)
(1S,4S,5R,6S)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid
CAS 191471-51-9C7H9NO5
![Ethyl (1S,5S,6R)-2-oxabicyclo[3.1.0]Hexane-6-carboxylate chemical structure, C8H12O3, CAS 202334-19-8](/s/WPWZXGZTADPNQW-XVMARJQXSA-N.svg)
Ethyl (1S,5S,6R)-2-oxabicyclo[3.1.0]Hexane-6-carboxylate
CAS 202334-19-8C8H12O3
![(1S,5S,6R)-2-Oxabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C6H8O3, CAS 1436006-59-5](/s/WWOUNQUZFPEFBG-LMVFSUKVSA-N.svg)
(1S,5S,6R)-2-Oxabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 1436006-59-5C6H8O3
![Rel-(1S,5S,6S)-2-oxabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C6H8O3, CAS 1436006-60-8](/s/WWOUNQUZFPEFBG-YUPRTTJUSA-N.svg)
Rel-(1S,5S,6S)-2-oxabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 1436006-60-8C6H8O3
2-Oxabicyclo(3.1.0)hexane-6-carboxylic acid
CAS 99418-15-2C6H8O3
![Ethyl (1S,4S,5R,6S)-4-hydroxy-2-oxabicyclo[3.1.0]hexane-6-carboxylate chemical structure, C8H12O4, CAS 1204678-19-2](/s/CCZIRRGQGLYOHA-BWBBJGPYSA-N.svg)
Ethyl (1S,4S,5R,6S)-4-hydroxy-2-oxabicyclo[3.1.0]hexane-6-carboxylate
CAS 1204678-19-2C8H12O4
2-Oxabicyclo(3.1.0)hexane
CAS 285-61-0C5H8O
![2-Oxabicyclo[3.1.0]hexane-6-carboxamide chemical structure, C6H9NO2, CAS 89598-52-7](/s/LCQXFWQCZQWPAE-UHFFFAOYSA-N.svg)
2-Oxabicyclo[3.1.0]hexane-6-carboxamide
CAS 89598-52-7C6H9NO2
(2-Oxabicyclo(3.1.0)hexan-6-yl)methanol
CAS 1363154-56-6C6H10O2
![2-Oxabicyclo[3.1.0]hexan-6-amine chemical structure, C5H9NO, CAS 1708160-40-0](/s/XASIPMMDCAZCGK-UHFFFAOYSA-N.svg)
2-Oxabicyclo[3.1.0]hexan-6-amine
CAS 1708160-40-0C5H9NO
![(2-Oxabicyclo[3.1.0]hexan-6-yl)methanamine chemical structure, C6H11NO, CAS 1559389-86-4](/s/AECSHWNFEPPOOE-UHFFFAOYSA-N.svg)
(2-Oxabicyclo[3.1.0]hexan-6-yl)methanamine
CAS 1559389-86-4C6H11NO
![(1R,5R)-2-Oxabicyclo[3.1.0]hexane-6-carboxylic acid chemical structure, C6H8O3, CAS 1098432-98-4](/s/WWOUNQUZFPEFBG-MCZAYYIJSA-N.svg)
(1R,5R)-2-Oxabicyclo[3.1.0]hexane-6-carboxylic acid
CAS 1098432-98-4C6H8O3
![2-(2-Oxabicyclo[3.1.0]hexan-6-yl)acetic acid chemical structure, C7H10O3, CAS 1936603-87-0](/s/BSJJLACUCPUTRB-UHFFFAOYSA-N.svg)
2-(2-Oxabicyclo[3.1.0]hexan-6-yl)acetic acid
CAS 1936603-87-0C7H10O3
![Methyl rel-(1S,5S,6R)-2-oxabicyclo[3.1.0]hexane-6-carboxylate chemical structure, C7H10O3, CAS 88376-04-9](/s/GXZWDGVVQCYWMR-JKUQZMGJSA-N.svg)
Methyl rel-(1S,5S,6R)-2-oxabicyclo[3.1.0]hexane-6-carboxylate
CAS 88376-04-9C7H10O3
![Methyl rel-(1S,5S,6S)-2-oxabicyclo[3.1.0]hexane-6-carboxylate chemical structure, C7H10O3, CAS 88333-11-3](/s/GXZWDGVVQCYWMR-ZLUOBGJFSA-N.svg)
Methyl rel-(1S,5S,6S)-2-oxabicyclo[3.1.0]hexane-6-carboxylate
CAS 88333-11-3C7H10O3
![(1R,3S,4S,5R)-6-(Hydroxymethyl)-3-methoxy-2-oxabicyclo[3.1.0]hexan-4-ol chemical structure, C7H12O4, CAS 167255-31-4](/s/PIBLCEBVQKWSOX-ZFYZTMLRSA-N.svg)
(1R,3S,4S,5R)-6-(Hydroxymethyl)-3-methoxy-2-oxabicyclo[3.1.0]hexan-4-ol
CAS 167255-31-4C7H12O4
![6,6-Difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile chemical structure, C6H5F2NO, CAS 1955557-96-6](/s/QXEUFJZNHZTJPU-UHFFFAOYSA-N.svg)
6,6-Difluoro-2-oxabicyclo[3.1.0]hexane-1-carbonitrile
CAS 1955557-96-6C6H5F2NO
![2-Oxabicyclo[3.1.0]hexane-6-carbaldehyde chemical structure, C6H8O2, CAS 1936358-04-1](/s/CMXMLOJMMZGSHS-UHFFFAOYSA-N.svg)
2-Oxabicyclo[3.1.0]hexane-6-carbaldehyde
CAS 1936358-04-1C6H8O2
- 6-(Azidomethyl)-2-oxabicyclo[3.1.0]hexane2920143-42-4C6H9N3O
- 2-Oxabicyclo[3.1.0]hexan-6-amine hcl2840022-16-2C5H10ClNO
- 2-Oxabicyclo[3.1.0]hexane-6-carbonitrile2110272-60-9C6H7NO
- tert-Butyl N-(2-oxabicyclo[3.1.0]hexan-6-yl)carbamate2940959-52-2C10H17NO3
- rac-(1R,5R,6R)-2-Oxabicyclo[3.1.0]hexan-6-amine2375250-41-0C5H9NO
Related scaffolds
Same ring framework with different atoms or bond orders
