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Murcko scaffold

Ring system with 2 rings and 6 atoms

130 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
6
Chemicals
130
With full pages
17
Scaffold SMILES

C1CC2OC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1CC2OC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 130 chemicals

6-Oxabicyclo[3.1.0]hexane-2-undecanoic acid methyl ester chemical structure, C17H30O3, CAS 6938-17-6
6-Oxabicyclo[3.1.0]hexane-2-undecanoic acid methyl ester
CAS 6938-17-6C17H30O3
6-Oxabicyclo[3.1.0]hexan-2-ol chemical structure, C5H8O2, CAS 765-54-8
6-Oxabicyclo[3.1.0]hexan-2-ol
CAS 765-54-8C5H8O2
3-Bromo-6-oxabicyclo[3.1.0]hexane chemical structure, C5H7BrO, CAS 80778-34-3
3-Bromo-6-oxabicyclo[3.1.0]hexane
CAS 80778-34-3C5H7BrO
3-Bromo-6-oxabicyclo[3.1.0]hexan-2-ol chemical structure, C5H7BrO2, CAS 16326-27-5
3-Bromo-6-oxabicyclo[3.1.0]hexan-2-ol
CAS 16326-27-5C5H7BrO2
1,5-Dimethyl-6-oxa-bicyclo(3.1.0)hexane chemical structure, C7H12O, CAS 82461-31-2
1,5-Dimethyl-6-oxa-bicyclo(3.1.0)hexane
CAS 82461-31-2C7H12O
4-(6-Oxabicyclo[3.1.0]hex-1-yl)-but-3-yn-2-one chemical structure, C9H10O2, CAS 959019-88-6
4-(6-Oxabicyclo[3.1.0]hex-1-yl)-but-3-yn-2-one
CAS 959019-88-6C9H10O2
6-Oxabicyclo(3.1.0)hexane-3-carbonitrile chemical structure, C6H7NO, CAS 53834-54-1
6-Oxabicyclo(3.1.0)hexane-3-carbonitrile
CAS 53834-54-1C6H7NO
6-Oxabicyclo[3.1.0]hexan-3-ol chemical structure, C5H8O2, CAS 175672-65-8
6-Oxabicyclo[3.1.0]hexan-3-ol
CAS 175672-65-8C5H8O2
1,2-Epoxycyclopentane chemical structure, C5H8O, CAS 285-67-6
1,2-Epoxycyclopentane
CAS 285-67-6C5H8O
Obhm-Me3N chemical structure, C10H20INO, CAS 159700-34-2
Obhm-Me3N
CAS 159700-34-2C10H20INO
1-Methyl-6-oxabicyclo(3.1.0)hexane chemical structure, C6H10O, CAS 16240-42-9
1-Methyl-6-oxabicyclo(3.1.0)hexane
CAS 16240-42-9C6H10O
3-Amino-6-oxabicyclo[3.1.0]hexane-3-carboxylic acid chemical structure, C6H9NO3, CAS 285996-78-3
3-Amino-6-oxabicyclo[3.1.0]hexane-3-carboxylic acid
CAS 285996-78-3C6H9NO3
2,2,2-Trifluoro-N-[(1R,5S)-6-oxabicyclo[3.1.0]hexan-3-yl]acetamide chemical structure, C7H8F3NO2, CAS 154705-97-2
2,2,2-Trifluoro-N-[(1R,5S)-6-oxabicyclo[3.1.0]hexan-3-yl]acetamide
CAS 154705-97-2C7H8F3NO2
(1R,3s,5S)-Methyl 6-oxabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C7H10O3, CAS 86941-00-6
(1R,3s,5S)-Methyl 6-oxabicyclo[3.1.0]hexane-3-carboxylate
CAS 86941-00-6C7H10O3
2-Propanone, 1-(6-oxabicyclo[3.1.0]hex-2-yl)-, (1alpha,2alpha,5alpha)-(9CI) chemical structure, C8H12O2, CAS 180980-77-2
2-Propanone, 1-(6-oxabicyclo[3.1.0]hex-2-yl)-, (1alpha,2alpha,5alpha)-(9CI)
CAS 180980-77-2C8H12O2
((1R,3r,5S)-rel-6-Oxabicyclo[3.1.0]hexan-3-yl)methanol chemical structure, C6H10O2, CAS 72598-06-2
((1R,3r,5S)-rel-6-Oxabicyclo[3.1.0]hexan-3-yl)methanol
CAS 72598-06-2C6H10O2
Ethyl (1S,5R)-6-oxabicyclo[3.1.0]hexane-3-carboxylate chemical structure, C8H12O3, CAS 1622218-77-2
Ethyl (1S,5R)-6-oxabicyclo[3.1.0]hexane-3-carboxylate
CAS 1622218-77-2C8H12O3
2-Propanone, 1-(6-oxabicyclo[3.1.0]hex-2-yl)-, (1alpha,2beta,5alpha)-(9CI) chemical structure, C8H12O2, CAS 180787-43-3
2-Propanone, 1-(6-oxabicyclo[3.1.0]hex-2-yl)-, (1alpha,2beta,5alpha)-(9CI)
CAS 180787-43-3C8H12O2
(1R,2R,5S)-6-Oxabicyclo[3.1.0]hexan-2-ol chemical structure, C5H8O2, CAS 120577-03-9
(1R,2R,5S)-6-Oxabicyclo[3.1.0]hexan-2-ol
CAS 120577-03-9C5H8O2
1-(5-Methyl-6-oxabicyclo[3.1.0]hexan-1-yl)ethanone chemical structure, C8H12O2, CAS 145801-12-3
1-(5-Methyl-6-oxabicyclo[3.1.0]hexan-1-yl)ethanone
CAS 145801-12-3C8H12O2
2-Methyl-6-oxabicyclo[3.1.0]hexane chemical structure, C6H10O, CAS 56084-29-8
2-Methyl-6-oxabicyclo[3.1.0]hexane
CAS 56084-29-8C6H10O
1-Ethyl-6-oxabicyclo[3.1.0]hexane chemical structure, C7H12O, CAS 30762-72-2
1-Ethyl-6-oxabicyclo[3.1.0]hexane
CAS 30762-72-2C7H12O
cis-6-Oxabicyclo[3.1.0]hexan-3-ol chemical structure, C5H8O2, CAS 25494-14-8
cis-6-Oxabicyclo[3.1.0]hexan-3-ol
CAS 25494-14-8C5H8O2
Rel-(1R,3r,5S)-1,5-dideuterio-6-oxabicyclo[3.1.0]hexan-3-ol chemical structure, C5H8O2, CAS 201535-42-4
Rel-(1R,3r,5S)-1,5-dideuterio-6-oxabicyclo[3.1.0]hexan-3-ol
CAS 201535-42-4C5H8O2