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Murcko scaffold

Ring system with 3 rings and 17 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
4
Scaffold SMILES

c1ccc(CNc2ccnc3[nH]ncc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNc2ccnc3[nH]ncc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-[Benzyl(ethyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C17H18N4O2, CAS 860785-50-8
4-[Benzyl(ethyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 860785-50-8C17H18N4O2
Ethyl 1-ethyl-4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C20H24N4O3, CAS 860785-52-0
Ethyl 1-ethyl-4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 860785-52-0C20H24N4O3
1-Ethyl-4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C18H20N4O3, CAS 860785-53-1
1-Ethyl-4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 860785-53-1C18H20N4O3
Ethyl 1-ethyl-3-methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C20H21F3N4O2, CAS 860785-55-3
Ethyl 1-ethyl-3-methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 860785-55-3C20H21F3N4O2
Ethyl 1-ethyl-3-methyl-4-{[4-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C20H21F3N4O2, CAS 860785-58-6
Ethyl 1-ethyl-3-methyl-4-{[4-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 860785-58-6C20H21F3N4O2
Ethyl 1-methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C18H17F3N4O2, CAS 692287-32-4
Ethyl 1-methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 692287-32-4C18H17F3N4O2
1-Methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C16H13F3N4O2, CAS 685109-25-5
1-Methyl-4-{[3-(trifluoromethyl)benzyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 685109-25-5C16H13F3N4O2
Ethyl 4-[(4-methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C18H20N4O3, CAS 685109-26-6
Ethyl 4-[(4-methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 685109-26-6C18H20N4O3
4-[(4-Methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C16H16N4O3, CAS 685109-27-7
4-[(4-Methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 685109-27-7C16H16N4O3
Ethyl 4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C18H20N4O3, CAS 860651-19-0
Ethyl 4-[(4-methoxybenzyl)amino]-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 860651-19-0C18H20N4O3
{4-[(4-Methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl}methanol chemical structure, C16H18N4O2, CAS 866131-42-2
{4-[(4-Methoxybenzyl)amino]-1-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl}methanol
CAS 866131-42-2C16H18N4O2
Ethyl 4-(benzylamino)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C17H18N4O2, CAS 160034-51-5
Ethyl 4-(benzylamino)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 160034-51-5C17H18N4O2
Ethyl 4-{[(4-chlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C17H17ClN4O2, CAS 1221715-35-0
Ethyl 4-{[(4-chlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 1221715-35-0C17H17ClN4O2
Ethyl 1-methyl-4-{[(4-methylphenyl)methyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C18H20N4O2, CAS 1221715-29-2
Ethyl 1-methyl-4-{[(4-methylphenyl)methyl]amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 1221715-29-2C18H20N4O2
Ethyl 4-{[(2,4-dichlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C17H16Cl2N4O2, CAS 1221715-33-8
Ethyl 4-{[(2,4-dichlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 1221715-33-8C17H16Cl2N4O2
4-[[(1-Ethylpyrazolo[3,4-b]pyridin-4-yl)amino]methyl]benzenesulfonamide chemical structure, C15H17N5O2S, CAS 2660180-80-1
4-[[(1-Ethylpyrazolo[3,4-b]pyridin-4-yl)amino]methyl]benzenesulfonamide
CAS 2660180-80-1C15H17N5O2S