Murcko scaffold
Ring system with 3 rings and 17 atoms
60 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 60
- With full pages
- 9
Scaffold SMILES
c1ccc(OCc2ccnc3ncnn23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 60 chemicals
![(R)-7-[1-(4-Chlorophenoxy)ethyl]-1,2,4-triazolo[1,5-a]pyrimidine chemical structure, C13H11ClN4O, CAS 165383-52-8](/s/FCEPUTGEUCVRRI-SECBINFHSA-N.svg)
(R)-7-[1-(4-Chlorophenoxy)ethyl]-1,2,4-triazolo[1,5-a]pyrimidine
CAS 165383-52-8C13H11ClN4O
![7-{1-[4-(tert-Butyl)phenoxy]ethyl}[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C17H21N5O, CAS 477865-05-7](/s/YUPCMIYNTMZQIN-UHFFFAOYSA-N.svg)
7-{1-[4-(tert-Butyl)phenoxy]ethyl}[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-05-7C17H21N5O
![7-(1-Phenoxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H13N5O, CAS 477865-07-9](/s/DSCTYAIKYWSTFP-UHFFFAOYSA-N.svg)
7-(1-Phenoxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-07-9C13H13N5O
![7-[1-(4-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C14H15N5O, CAS 477865-11-5](/s/HQRKNRDNODFOSI-UHFFFAOYSA-N.svg)
7-[1-(4-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-11-5C14H15N5O
![7-[1-(2,6-Dichlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H11Cl2N5O, CAS 477865-30-8](/s/BZOGUTPVKPQHHA-UHFFFAOYSA-N.svg)
7-[1-(2,6-Dichlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-30-8C13H11Cl2N5O
![7-(1-(3-Chlorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H12ClN5O, CAS 477865-76-2](/s/PLLDZKCQZUJJFR-UHFFFAOYSA-N.svg)
7-(1-(3-Chlorophenoxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-76-2C13H12ClN5O
![7-[1-(3-Methoxyphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C14H15N5O2, CAS 306979-54-4](/s/FHTDCFVEGSHBLW-UHFFFAOYSA-N.svg)
7-[1-(3-Methoxyphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 306979-54-4C14H15N5O2
![7-[1-(3-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C14H14N4O, CAS 306979-57-7](/s/HHOSMXBSJPXCEQ-UHFFFAOYSA-N.svg)
7-[1-(3-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 306979-57-7C14H14N4O
![7-[1-(3-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C14H15N5O, CAS 306979-61-3](/s/ZJRYBPAIBUZCOY-UHFFFAOYSA-N.svg)
7-[1-(3-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 306979-61-3C14H15N5O
![7-[1-(3,5-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C15H17N5O, CAS 306979-66-8](/s/KDUIDBRJNDIFTO-UHFFFAOYSA-N.svg)
7-[1-(3,5-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 306979-66-8C15H17N5O
![7-[1-(3,5-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C15H16N4O, CAS 306979-70-4](/s/IRLOIJPDFNPVLM-UHFFFAOYSA-N.svg)
7-[1-(3,5-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 306979-70-4C15H16N4O
![7-{1-[3-(Trifluoromethyl)phenoxy]ethyl}-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C14H12F3N5O, CAS 306979-68-0](/s/RXPWVZSANXRTAY-UHFFFAOYSA-N.svg)
7-{1-[3-(Trifluoromethyl)phenoxy]ethyl}-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 306979-68-0C14H12F3N5O
![7-[1-(3-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H11ClN4O, CAS 165383-25-5](/s/ZRVJOPMTANXDOX-UHFFFAOYSA-N.svg)
7-[1-(3-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 165383-25-5C13H11ClN4O
![7-[1-(2-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H11FN4O, CAS 477865-08-0](/s/XJQALWLMESTHMC-UHFFFAOYSA-N.svg)
7-[1-(2-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 477865-08-0C13H11FN4O
![7-[1-(3-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H11FN4O, CAS 477865-06-8](/s/ARVXSBJANQWERD-UHFFFAOYSA-N.svg)
7-[1-(3-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 477865-06-8C13H11FN4O
![7-[1-(4-tert-Butylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C17H20N4O, CAS 477865-21-7](/s/UIVGPGSWACZQDC-UHFFFAOYSA-N.svg)
7-[1-(4-tert-Butylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 477865-21-7C17H20N4O
![7-[1-(2-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H12ClN5O, CAS 477865-28-4](/s/RQIHETACXYQPEJ-UHFFFAOYSA-N.svg)
7-[1-(2-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-28-4C13H12ClN5O
![7-[1-(2-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H11ClN4O, CAS 477865-32-0](/s/BETMYCLJHTVAJX-UHFFFAOYSA-N.svg)
7-[1-(2-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 477865-32-0C13H11ClN4O
![7-[1-(3-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H12FN5O, CAS 477865-03-5](/s/AQDXKHKHMZZAGL-UHFFFAOYSA-N.svg)
7-[1-(3-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-03-5C13H12FN5O
![7-[1-(2-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C13H12FN5O, CAS 477865-09-1](/s/HPWRHVHKMDGSHR-UHFFFAOYSA-N.svg)
7-[1-(2-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-09-1C13H12FN5O
![7-(1-Phenoxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H12N4O, CAS 320416-74-8](/s/FNIGKRUEDGCZJM-UHFFFAOYSA-N.svg)
7-(1-Phenoxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 320416-74-8C13H12N4O
CM-Tpmf
C16H17ClN6O2
![7-[1-(2,6-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine chemical structure, C15H17N5O, CAS 477865-17-1](/s/DUHPIFKPBYGVEP-UHFFFAOYSA-N.svg)
7-[1-(2,6-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine
CAS 477865-17-1C15H17N5O
![7-[1-(2,4-Dichlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine chemical structure, C13H10Cl2N4O, CAS 165383-28-8](/s/CWJSGPLPYFBOGX-UHFFFAOYSA-N.svg)
7-[1-(2,4-Dichlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine
CAS 165383-28-8C13H10Cl2N4O
- 7-[1-(4-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine165383-12-0C13H11ClN4O
- 7-[1-(2,4-Difluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine165383-26-6C13H10F2N4O
- 7-[1-(4-Methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine477865-23-9C14H14N4O
- 7-[1-(2,6-Dichlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine477865-67-1C13H10Cl2N4O
- 7-[1-(4-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine339097-09-5C13H12FN5O
- 4-Nitrophenyl 1-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylethyl ether477865-14-8C13H11N5O3
- 4-(1-[1,2,4]Triazolo[1,5-a]pyrimidin-7-ylethoxy)benzenecarbonitrile165383-21-1C14H11N5O
- 7-{1-[3-(Trifluoromethyl)phenoxy]ethyl}-[1,2,4]triazolo[1,5-a]pyrimidine477865-02-4C14H11F3N4O
- 7-[1-(2,4-Dichlorophenoxy)ethyl]-2-(methylsulfanyl)[1,2,4]triazolo[1,5-a]pyrimidine338403-67-1C14H12Cl2N4OS
- 7-[1-(4-Chloro-2-methylphenoxy)ethyl][1,2,4]triazolo[1,5-a]pyrimidin-2-amine477865-04-6C14H14ClN5O
- B-Tpmf477865-65-9C19H24N6O2
- 7-[1-(2,4-Difluorophenoxy)ethyl][1,2,4]triazolo[1,5-a]pyrimidin-2-amine477864-98-5C13H11F2N5O
- 7-[1-(4-Nitrophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine477865-13-7C13H12N6O3
- 7-[1-(4-Chloro-2-methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine477865-20-6C14H13ClN4O
- N'-[7-[1-(3,5-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylmethanimidamide477865-49-9C18H22N6O
- N,N-Dimethyl-N'-[7-(1-phenoxyethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methanimidamide477865-43-3C16H18N6O
- N'-[7-[1-(4-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylmethanimidamide303146-21-6C16H17FN6O
- N'-[7-[(1S)-1-(4-Chloro-2-methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N-methoxymethanimidamideC16H17ClN6O2
- (E)-N-{7-[1-(4-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxymethanimidamide303146-23-8C15H15FN6O2
- N-Methoxy-N'-[7-[1-(4-nitrophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]methanimidamide477865-57-9C15H15N7O4
- (E)-N-{7-[1-(4-Chloro-2-methylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N'-methoxymethanimidamide477865-59-1C16H17ClN6O2
- N'-[7-[1-(3-Methoxyphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylmethanimidamide477865-40-0C17H20N6O2
- N'-[7-[1-(2,4-Difluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylmethanimidamide477865-42-2C16H16F2N6O
- N'-[7-[1-(3-Chlorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylmethanimidamide338775-05-6C16H17ClN6O
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