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Murcko scaffold

2-Cyclobutyl-1H-imidazole scaffold

80 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
80
With full pages
5
Scaffold SMILES

c1c[nH]c(C2CCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Cyclobutyl-1H-imidazole page
Murcko scaffold c1c[nH]c(C2CCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

2-(1-Aminocyclobutyl)-1H-imidazole-4-carboxylic acid chemical structure, C8H11N3O2, CAS 1110909-14-2
2-(1-Aminocyclobutyl)-1H-imidazole-4-carboxylic acid
CAS 1110909-14-2C8H11N3O2
2-Cyclobutyl-1H-imidazole chemical structure, C7H10N2, CAS 89943-00-0
2-Cyclobutyl-1H-imidazole
CAS 89943-00-0C7H10N2
Methyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate chemical structure, C9H13N3O2, CAS 1183958-63-5
Methyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate
CAS 1183958-63-5C9H13N3O2
2-[1-(2,2,2-Trifluoroacetamido)cyclobutyl]-1H-imidazole-4-carboxylic acid chemical structure, C10H10F3N3O3, CAS 1183888-13-2
2-[1-(2,2,2-Trifluoroacetamido)cyclobutyl]-1H-imidazole-4-carboxylic acid
CAS 1183888-13-2C10H10F3N3O3
tert-Butyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate chemical structure, C12H19N3O2, CAS 1182997-67-6
tert-Butyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate
CAS 1182997-67-6C12H19N3O2
2-(1-Acetamidocyclobutyl)-1H-imidazole-4-carboxylic acid chemical structure, C10H13N3O3, CAS 1179162-04-9
2-(1-Acetamidocyclobutyl)-1H-imidazole-4-carboxylic acid
CAS 1179162-04-9C10H13N3O3
2-(1-((tert-Butoxycarbonyl)amino)cyclobutyl)-1H-imidazole-4-carboxylic acid chemical structure, C13H19N3O4, CAS 1179012-71-5
2-(1-((tert-Butoxycarbonyl)amino)cyclobutyl)-1H-imidazole-4-carboxylic acid
CAS 1179012-71-5C13H19N3O4
Ethyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate chemical structure, C10H15N3O2, CAS 1182804-70-1
Ethyl 2-(1-aminocyclobutyl)-1H-imidazole-4-carboxylate
CAS 1182804-70-1C10H15N3O2
2-(1-{[(Prop-2-en-1-yloxy)carbonyl]amino}cyclobutyl)-1H-imidazole-4-carboxylic acid chemical structure, C12H15N3O4, CAS 1410182-96-5
2-(1-{[(Prop-2-en-1-yloxy)carbonyl]amino}cyclobutyl)-1H-imidazole-4-carboxylic acid
CAS 1410182-96-5C12H15N3O4
2-Cyclobutyl-1H-imidazole-4-carbaldehyde chemical structure, C8H10N2O, CAS 1485121-64-9
2-Cyclobutyl-1H-imidazole-4-carbaldehyde
CAS 1485121-64-9C8H10N2O
(1s,3s)-3-Amino-1-(1-methyl-1H-imidazol-2-yl)cyclobutan-1-ol chemical structure, C8H13N3O, CAS 2680534-76-1
(1s,3s)-3-Amino-1-(1-methyl-1H-imidazol-2-yl)cyclobutan-1-ol
CAS 2680534-76-1C8H13N3O
1-(1H-Imidazol-2-yl)cyclobutan-1-amine chemical structure, C7H11N3, CAS 1515053-03-8
1-(1H-Imidazol-2-yl)cyclobutan-1-amine
CAS 1515053-03-8C7H11N3
1-(1-Methyl-1H-imidazol-2-yl)cyclobutan-1-amine chemical structure, C8H13N3, CAS 1537850-28-4
1-(1-Methyl-1H-imidazol-2-yl)cyclobutan-1-amine
CAS 1537850-28-4C8H13N3
1-[1-(1H-Imidazol-2-yl)cyclobutyl]methanamine chemical structure, C8H13N3, CAS 1511581-89-7
1-[1-(1H-Imidazol-2-yl)cyclobutyl]methanamine
CAS 1511581-89-7C8H13N3
1-[1-(1-Methyl-1H-imidazol-2-yl)cyclobutyl]methanamine chemical structure, C9H15N3, CAS 1503535-49-6
1-[1-(1-Methyl-1H-imidazol-2-yl)cyclobutyl]methanamine
CAS 1503535-49-6C9H15N3
1-(1H-Imidazol-2-yl)cyclobutane-1-carboxylic acid chemical structure, C8H10N2O2, CAS 1540993-55-2
1-(1H-Imidazol-2-yl)cyclobutane-1-carboxylic acid
CAS 1540993-55-2C8H10N2O2
1-(1-Methyl-1H-imidazol-2-yl)cyclobutane-1-carboxylic acid chemical structure, C9H12N2O2, CAS 1502161-86-5
1-(1-Methyl-1H-imidazol-2-yl)cyclobutane-1-carboxylic acid
CAS 1502161-86-5C9H12N2O2
(2-(1-Aminocyclobutyl)-1H-imidazol-4-yl)methanol chemical structure, C8H13N3O, CAS 1774892-32-8
(2-(1-Aminocyclobutyl)-1H-imidazol-4-yl)methanol
CAS 1774892-32-8C8H13N3O
1-(1-Methyl-1H-imidazol-2-yl)cyclobutane-1-carbonitrile chemical structure, C9H11N3, CAS 1368614-43-0
1-(1-Methyl-1H-imidazol-2-yl)cyclobutane-1-carbonitrile
CAS 1368614-43-0C9H11N3
5-Bromo-2-cyclobutyl-1H-imidazole chemical structure, C7H9BrN2, CAS 1279123-47-5
5-Bromo-2-cyclobutyl-1H-imidazole
CAS 1279123-47-5C7H9BrN2
3-(1H-Imidazol-2-yl)cyclobutan-1-amine dihydrochloride chemical structure, C7H13Cl2N3, CAS 2230799-85-4
3-(1H-Imidazol-2-yl)cyclobutan-1-amine dihydrochloride
CAS 2230799-85-4C7H13Cl2N3
3-(1H-Imidazol-2-yl)cyclobutan-1-amine chemical structure, C7H11N3, CAS 1971123-97-3
3-(1H-Imidazol-2-yl)cyclobutan-1-amine
CAS 1971123-97-3C7H11N3
1-(4-Methyl-1H-imidazol-2-yl)cyclobutan-1-amine dihydrochloride chemical structure, C8H15Cl2N3, CAS 2094857-63-1
1-(4-Methyl-1H-imidazol-2-yl)cyclobutan-1-amine dihydrochloride
CAS 2094857-63-1C8H15Cl2N3
1-(1-Ethyl-1H-imidazol-2-yl)cyclobutan-1-amine chemical structure, C9H15N3, CAS 1865121-80-7
1-(1-Ethyl-1H-imidazol-2-yl)cyclobutan-1-amine
CAS 1865121-80-7C9H15N3