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Murcko scaffold

Ring system with 2 rings and 17 atoms

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
9
With full pages
3
Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1ncccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)Nc1ncccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(2E)-N-(4,6-Dimethylpyrimidin-2-yl)-3-phenylprop-2-enamide chemical structure, C15H15N3O, CAS 328119-33-1
(2E)-N-(4,6-Dimethylpyrimidin-2-yl)-3-phenylprop-2-enamide
CAS 328119-33-1C15H15N3O
(2E)-3-(3,4-Dimethoxyphenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide chemical structure, C17H19N3O3, CAS 1164491-53-5
(2E)-3-(3,4-Dimethoxyphenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide
CAS 1164491-53-5C17H19N3O3
(E)-3-(2-Chlorophenyl)-N-pyrimidin-2-ylprop-2-enamide chemical structure, C13H10ClN3O, CAS 349419-80-3
(E)-3-(2-Chlorophenyl)-N-pyrimidin-2-ylprop-2-enamide
CAS 349419-80-3C13H10ClN3O
(E)-3-(2-Chlorophenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide chemical structure, C15H14ClN3O, CAS 1164451-36-8
(E)-3-(2-Chlorophenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide
CAS 1164451-36-8C15H14ClN3O
(E)-3-(2-Nitrophenyl)-N-pyrimidin-2-ylprop-2-enamide chemical structure, C13H10N4O3, CAS 600122-77-8
(E)-3-(2-Nitrophenyl)-N-pyrimidin-2-ylprop-2-enamide
CAS 600122-77-8C13H10N4O3
(E)-3-(4-Chlorophenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide chemical structure, C15H14ClN3O, CAS 433955-66-9
(E)-3-(4-Chlorophenyl)-N-(4,6-dimethylpyrimidin-2-yl)prop-2-enamide
CAS 433955-66-9C15H14ClN3O
2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C17H16N4O4, CAS 300695-93-6
2-Cyano-N-(4,6-dimethoxypyrimidin-2-yl)-3-(4-methoxyphenyl)prop-2-enamide
CAS 300695-93-6C17H16N4O4
2-Cyano-N-(4,6-dichloropyrimidin-2-yl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C15H10Cl2N4O2, CAS 300851-52-9
2-Cyano-N-(4,6-dichloropyrimidin-2-yl)-3-(4-methoxyphenyl)prop-2-enamide
CAS 300851-52-9C15H10Cl2N4O2
3-Phenyl-N-pyrimidin-2-ylprop-2-enamide chemical structure, C13H11N3O, CAS 18602-66-9
3-Phenyl-N-pyrimidin-2-ylprop-2-enamide
CAS 18602-66-9C13H11N3O