Murcko scaffold
N-Phenethylbenzenesulfonamide scaffold
671 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 671
- With full pages
- 83
Scaffold SMILES
O=S(=O)(NCCc1ccccc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 671 chemicals
N-(3-Chloro-2-oxo-1-(phenylmethyl)propyl)-4-methylbenzenesulfonamide
CAS 329-30-6C17H18ClNO3S
Alanine, N-(p-bromobenzenesulfonyl)-3-phenyl-, DL-
CAS 37642-61-8C15H14BrNO4S
Alanine, N-benzenesulfonyl-3-phenyl-, DL-
CAS 40279-93-4C15H15NO4S
N-((4-Bromophenyl)sulfonyl)-D-phenylalanine
CAS 40279-98-9C15H14BrNO4S
Alanine, 3-(p-hydroxyphenyl)-N-(p-tolylsulfonyl)-, cyanomethyl ester, L-
CAS 64187-18-4C18H18N2O5S
Cyanomethyl N-(4-methylbenzene-1-sulfonyl)phenylalaninate
CAS 64187-44-6C18H18N2O4S
Sulotroban
CAS 72131-33-0C16H17NO5S
Daltroban
CAS 79094-20-5C16H16ClNO4S
N-((4-Methylphenyl)sulfonyl)-L-phenylalanine
CAS 13505-32-3C16H17NO4S
1-Tosylamido-2-phenylethyldiazomethylketone
CAS 10119-00-3C17H17N3O3S
N-Phenethyl-p-toluenesulfonamide
CAS 5450-75-9C15H17NO2S
N-Phenethylbenzenesulfonamide
CAS 77198-99-3C14H15NO2S
![4-{[2-(4-Aminophenyl)ethyl]sulfamoyl}benzenesulfonyl fluoride chemical structure, C14H15FN2O4S2, CAS 21316-00-7](/s/VAICXSJDZFJJNZ-UHFFFAOYSA-N.svg)
4-{[2-(4-Aminophenyl)ethyl]sulfamoyl}benzenesulfonyl fluoride
CAS 21316-00-7C14H15FN2O4S2
![2-[2-(3,4-Dimethoxyphenyl)ethyl-(4-methylphenyl)sulfonylamino]acetic acid chemical structure, C19H23NO6S, CAS 56014-50-7](/s/VRNYMQWGEYZMFP-UHFFFAOYSA-N.svg)
2-[2-(3,4-Dimethoxyphenyl)ethyl-(4-methylphenyl)sulfonylamino]acetic acid
CAS 56014-50-7C19H23NO6S
3-(N-(4-Aminophenethyl)sulfamoyl)benzene-1-sulfonyl fluoride
CAS 21316-01-8C14H15FN2O4S2
N-(3-Bromo-2-phenylpropyl)benzenesulfonamide
CAS 78515-42-1C15H16BrNO2S
![2-([(4-Methylphenyl)sulfonyl]amino)-3-phenylpropanoic acid chemical structure, C16H17NO4S, CAS 34635-34-2](/s/CGRCVIZBNRUWLY-UHFFFAOYSA-N.svg)
2-([(4-Methylphenyl)sulfonyl]amino)-3-phenylpropanoic acid
CAS 34635-34-2C16H17NO4S
Ethyl N-(4-methylbenzene-1-sulfonyl)tyrosinate
CAS 58559-09-4C18H21NO5S
![Methyl 2-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoate chemical structure, C17H19NO4S, CAS 51220-86-1](/s/INTVRPHGRLWXBI-UHFFFAOYSA-N.svg)
Methyl 2-{[(4-methylphenyl)sulfonyl]amino}-3-phenylpropanoate
CAS 51220-86-1C17H19NO4S
Nalpha-Tosyl-L-phenylalanine chloromethyl ketone
CAS 402-71-1C17H18ClNO3S
![2-{[(4-Nitrophenyl)sulfonyl]amino}-3-phenylpropanoic acid chemical structure, C15H14N2O6S, CAS 1638102-70-1](/s/JVHRPLXWZFPXIJ-UHFFFAOYSA-N.svg)
2-{[(4-Nitrophenyl)sulfonyl]amino}-3-phenylpropanoic acid
CAS 1638102-70-1C15H14N2O6S
N-p-Toluenesulfonyltyrosine
CAS 6297-78-5C16H17NO5S
![2-[(4-Nitrophenyl)sulfonylamino]-3-phenylpropanoyl chloride chemical structure, C15H13ClN2O5S](/s/RYQIQECSYJRDBT-UHFFFAOYSA-N.svg)
2-[(4-Nitrophenyl)sulfonylamino]-3-phenylpropanoyl chloride
C15H13ClN2O5S
![N-[2-(4-Methoxyphenyl)ethyl]-4-methylsulfanylbenzenesulfonamide chemical structure, C16H19NO3S2, CAS 381679-96-5](/s/RQQQKUPKZGVHGT-UHFFFAOYSA-N.svg)
N-[2-(4-Methoxyphenyl)ethyl]-4-methylsulfanylbenzenesulfonamide
CAS 381679-96-5C16H19NO3S2
- 4-Chloro-N-[2-(3,4-diethoxyphenyl)ethyl]benzenesulfonamide446028-70-2C18H22ClNO4S
- 2,5-Dimethoxy-N-(2-phenylethyl)benzenesulfonamide457960-86-0C16H19NO4S
- N-(3-Hydroxy-propyl)-2-[(4-methoxy-benzenesulfonyl)-phenethyl-amino]-acetamide381697-59-2C20H26N2O5S
- 4-Fluoro-N-(2-phenylethyl)benzenesulfonamide346690-00-4C14H14FNO2S
- N-(4-(((2-Phenylethyl)amino)sulfonyl)phenyl)ethanamide289061-22-9C16H18N2O3S
- 4-Nitro-N-phenethylbenzenesulfonamide52374-24-0C14H14N2O4S
- N-Tosyl-D-phenylalanine86117-53-5C16H17NO4S
- (S)-(-)-N-(1-(Hydroxymethyl)-2-phenylethyl)-4-methylbenzenesulfonamide82495-70-3C16H19NO3S
- (2S)-2-(2-Fluorobenzenesulfonamido)-3-phenylpropanoic acid1212370-86-9C15H14FNO4S
- 2,6-Dichloro-N-(2-phenylethyl)benzenesulfonamide19818-08-7C14H13Cl2NO2S
- 2 suppliersN-[2-(3,4-Dimethoxyphenyl)ethyl]-4-methylbenzene-1-sulfonamide14165-67-4C17H21NO4S
- N-[(3,4-Dimethylphenyl)sulfonyl]-L-phenylalanine381687-96-3C17H19NO4S
- Urea, 1-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-26-3C19H24ClN3O6S2
- Urea, 1-butyl-3-((p-(2-(3-chloro-6-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-81514-27-4C20H26ClN3O6S2
- Benzenesulfonamide, 2-methoxy-5-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-28-5C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-5-nitro-81514-29-6C20H26N4O8S2
- Benzenesulfonamide, 2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-31-0C19H24N4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-4-nitro-81514-32-1C20H26N4O8S2
- Benzenesulfonamide, 5-chloro-2-methoxy-4-nitro-N-(2-(4-((((propylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-81514-34-3C19H23ClN4O8S2
- Benzenesulfonamide, N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-4-nitro-81514-35-4C20H25ClN4O8S2
- Urea, 1-((p-(2-(4-amino-5-chloro-2-methoxybenzenesulfonamido)ethyl)phenyl)sulfonyl)-3-propyl-81514-37-6C19H25ClN4O6S2
- Benzenesulfonamide, 4-amino-N-(2-(4-((((butylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-chloro-2-methoxy-81514-38-7C20H27ClN4O6S2
- L-Phenylalanine, N-((4-(((2-methylpropoxy)carbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-24-9C22H28N2O6S
- L-Phenylalanine, N-((4-((ethoxycarbonyl)amino)phenyl)sulfonyl)-, ethyl ester81865-25-0C20H24N2O6S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals
O=C(NCc1ccccc1)Nc1ccccc171 chemicals