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Murcko scaffold

5-Phenyl-4-piperazin-1-yl-thieno[2,3-d]pyrimidine scaffold

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
20
With full pages
6
Scaffold SMILES

c1ccc(-c2csc3ncnc(N4CCNCC4)c23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Phenyl-4-piperazin-1-yl-thieno[2,3-d]pyrimidine page
Murcko scaffold c1ccc(-c2csc3ncnc(N4CCNCC4)c23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-[5-(4-Methoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]-4-methylpiperazine chemical structure, C18H20N4OS, CAS 345615-33-0
1-[5-(4-Methoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]-4-methylpiperazine
CAS 345615-33-0C18H20N4OS
6-Methyl-4-(4-methylpiperazin-1-yl)-5-(p-tolyl)thieno[2,3-d]pyrimidine chemical structure, C19H22N4S, CAS 670270-91-4
6-Methyl-4-(4-methylpiperazin-1-yl)-5-(p-tolyl)thieno[2,3-d]pyrimidine
CAS 670270-91-4C19H22N4S
6-Methyl-4-(4-methylpiperazin-1-yl)-5-phenylthieno[2,3-d]pyrimidine chemical structure, C18H20N4S, CAS 381731-36-8
6-Methyl-4-(4-methylpiperazin-1-yl)-5-phenylthieno[2,3-d]pyrimidine
CAS 381731-36-8C18H20N4S
5-Phenyl-4-piperazin-1-yl-thieno[2,3-d]pyrimidine chemical structure, C16H16N4S, CAS 278791-71-2
5-Phenyl-4-piperazin-1-yl-thieno[2,3-d]pyrimidine
CAS 278791-71-2C16H16N4S
2-[4-(5-Phenylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol chemical structure, C18H20N4OS, CAS 327980-21-2
2-[4-(5-Phenylthieno[2,3-d]pyrimidin-4-yl)piperazin-1-yl]ethanol
CAS 327980-21-2C18H20N4OS
4-(4-Ethylpiperazin-1-yl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine chemical structure, C18H19FN4S, CAS 670255-15-9
4-(4-Ethylpiperazin-1-yl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidine
CAS 670255-15-9C18H19FN4S
5-(4-Chlorophenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C17H17ClN4S, CAS 384369-71-5
5-(4-Chlorophenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 384369-71-5C17H17ClN4S
4-(4-Methylpiperazin-1-yl)-5-phenylthieno[2,3-d]pyrimidine chemical structure, C17H18N4S, CAS 433318-01-5
4-(4-Methylpiperazin-1-yl)-5-phenylthieno[2,3-d]pyrimidine
CAS 433318-01-5C17H18N4S
1-Methyl-4-{5-[4-(propan-2-yl)phenyl]thieno[2,3-d]pyrimidin-4-yl}piperazine chemical structure, C20H24N4S, CAS 379246-60-3
1-Methyl-4-{5-[4-(propan-2-yl)phenyl]thieno[2,3-d]pyrimidin-4-yl}piperazine
CAS 379246-60-3C20H24N4S
5-(4-Chlorophenyl)-4-(4-(2-methylallyl)piperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C20H21ClN4S, CAS 329709-00-4
5-(4-Chlorophenyl)-4-(4-(2-methylallyl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 329709-00-4C20H21ClN4S
5-(4-Chlorophenyl)-4-(4-ethylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C18H19ClN4S, CAS 315709-69-4
5-(4-Chlorophenyl)-4-(4-ethylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 315709-69-4C18H19ClN4S
2-{4-[5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl}ethanol chemical structure, C18H19FN4OS, CAS 384376-11-8
2-{4-[5-(4-Fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl}ethanol
CAS 384376-11-8C18H19FN4OS
5-(3,4-Dimethylphenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C19H22N4S, CAS 670270-33-4
5-(3,4-Dimethylphenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 670270-33-4C19H22N4S
5-(4-Chlorophenyl)-6-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C18H19ClN4S, CAS 670270-90-3
5-(4-Chlorophenyl)-6-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 670270-90-3C18H19ClN4S
4-(4-Ethylpiperazin-1-yl)-5-(4-fluorophenyl)-6-methylthieno[2,3-d]pyrimidine chemical structure, C19H21FN4S, CAS 670270-92-5
4-(4-Ethylpiperazin-1-yl)-5-(4-fluorophenyl)-6-methylthieno[2,3-d]pyrimidine
CAS 670270-92-5C19H21FN4S
5-(2-Chlorophenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C17H17ClN4S, CAS 496026-35-8
5-(2-Chlorophenyl)-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine
CAS 496026-35-8C17H17ClN4S
1-[5-(4-Bromophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-(prop-2-yn-1-yl)piperazine chemical structure, C19H17BrN4S, CAS 941034-91-9
1-[5-(4-Bromophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-(prop-2-yn-1-yl)piperazine
CAS 941034-91-9C19H17BrN4S
1-[5-(4-Chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-(prop-2-yn-1-yl)piperazine chemical structure, C19H17ClN4S, CAS 949242-02-8
1-[5-(4-Chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]-4-(prop-2-yn-1-yl)piperazine
CAS 949242-02-8C19H17ClN4S
5-(4-Chlorophenyl)-4-(1-piperazinyl)-thieno[2,3-d]pyrimidine hydrochloride chemical structure, C16H16Cl2N4S, CAS 1698026-47-9
5-(4-Chlorophenyl)-4-(1-piperazinyl)-thieno[2,3-d]pyrimidine hydrochloride
CAS 1698026-47-9C16H16Cl2N4S
tert-Butyl 4-(5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylate chemical structure, C21H23ClN4O2S, CAS 1698026-46-8
tert-Butyl 4-(5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl)piperazine-1-carboxylate
CAS 1698026-46-8C21H23ClN4O2S