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Murcko scaffold

2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(phenylmethyl)- scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
5
Scaffold SMILES

O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(phenylmethyl)- page
Murcko scaffold O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(phenylmethyl)- chemical structure, C20H19N3O2, CAS 82597-82-8
2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(phenylmethyl)-
CAS 82597-82-8C20H19N3O2
Thaxtomine A chemical structure, C22H22N4O6, CAS 122380-18-1
Thaxtomine A
CAS 122380-18-1C22H22N4O6
Thaxtomine B chemical structure, C22H22N4O5, CAS 122380-19-2
Thaxtomine B
CAS 122380-19-2C22H22N4O5
Cyclo(-D-Trp-Tyr) chemical structure, C20H19N3O3, CAS 852955-00-1
Cyclo(-D-Trp-Tyr)
CAS 852955-00-1C20H19N3O3
(11S,14S)-Cyclo-(L-Trp-L-Phe) chemical structure, C20H19N3O2, CAS 6521-48-8
(11S,14S)-Cyclo-(L-Trp-L-Phe)
CAS 6521-48-8C20H19N3O2
25Piperazinedione, indole derivative chemical structure, C20H19N3O3, CAS 20829-53-2
25Piperazinedione, indole derivative
CAS 20829-53-2C20H19N3O3
Thaxtomin C chemical structure, C21H20N4O4, CAS 140111-05-3
Thaxtomin C
CAS 140111-05-3C21H20N4O4
(3R,6R)-3-Benzyl-6-[(1H-indol-3-yl)methyl]piperazine-2,5-dione chemical structure, C20H19N3O2, CAS 92842-17-6
(3R,6R)-3-Benzyl-6-[(1H-indol-3-yl)methyl]piperazine-2,5-dione
CAS 92842-17-6C20H19N3O2
(3S,6R)-3-((1H-Indol-3-yl)methyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione chemical structure, C20H19N3O3, CAS 107911-05-7
(3S,6R)-3-((1H-Indol-3-yl)methyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione
CAS 107911-05-7C20H19N3O3
Quellenin chemical structure, C21H21N3O3, CAS 2243042-31-9
Quellenin
CAS 2243042-31-9C21H21N3O3