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Murcko scaffold

3-[(4-Benzoyl-1-piperazinyl)methyl]-1H-indole scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(c1ccccc1)N1CCN(Cc2c[nH]c3ccccc23)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-[(4-Benzoyl-1-piperazinyl)methyl]-1H-indole page
Murcko scaffold O=C(c1ccccc1)N1CCN(Cc2c[nH]c3ccccc23)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-{[4-(4-Fluorobenzoyl)-1-piperazinyl]methyl}-1H-indole chemical structure, C20H20FN3O, CAS 500001-75-2
3-{[4-(4-Fluorobenzoyl)-1-piperazinyl]methyl}-1H-indole
CAS 500001-75-2C20H20FN3O
3-[(4-Benzoyl-1-piperazinyl)methyl]-1H-indole chemical structure, C20H21N3O, CAS 353772-99-3
3-[(4-Benzoyl-1-piperazinyl)methyl]-1H-indole
CAS 353772-99-3C20H21N3O
3-{[4-(2-Methoxybenzoyl)-1-piperazinyl]methyl}-1H-indole chemical structure, C21H23N3O2, CAS 423742-66-9
3-{[4-(2-Methoxybenzoyl)-1-piperazinyl]methyl}-1H-indole
CAS 423742-66-9C21H23N3O2
[4-(1H-Indol-3-ylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone chemical structure, C23H27N3O4, CAS 332124-95-5
[4-(1H-Indol-3-ylmethyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
CAS 332124-95-5C23H27N3O4
(3,5-Dimethoxyphenyl)-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]methanone chemical structure, C22H25N3O3, CAS 442651-41-4
(3,5-Dimethoxyphenyl)-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]methanone
CAS 442651-41-4C22H25N3O3
3-{[4-(3-Chlorobenzoyl)-1-piperazinyl]methyl}-1H-indole chemical structure, C20H20ClN3O, CAS 441743-35-7
3-{[4-(3-Chlorobenzoyl)-1-piperazinyl]methyl}-1H-indole
CAS 441743-35-7C20H20ClN3O
(2,3-Dimethoxyphenyl)-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]methanone chemical structure, C22H25N3O3, CAS 332899-05-5
(2,3-Dimethoxyphenyl)-[4-(1H-indol-3-ylmethyl)piperazin-1-yl]methanone
CAS 332899-05-5C22H25N3O3
[4-(1H-Indol-3-ylmethyl)piperazin-1-yl]-(4-nitrophenyl)methanone chemical structure, C20H20N4O3, CAS 332161-21-4
[4-(1H-Indol-3-ylmethyl)piperazin-1-yl]-(4-nitrophenyl)methanone
CAS 332161-21-4C20H20N4O3