CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
14
With full pages
5
Scaffold SMILES

O=c1cc(CN2CCN(CC=Cc3ccccc3)CC2)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(CN2CCN(CC=Cc3ccccc3)CC2)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-7,8-dimethyl-2H-chromen-2-one chemical structure, C25H28N2O2, CAS 556020-65-6
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-7,8-dimethyl-2H-chromen-2-one
CAS 556020-65-6C25H28N2O2
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6,8-dimethyl-2H-chromen-2-one chemical structure, C25H28N2O2, CAS 899397-99-0
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6,8-dimethyl-2H-chromen-2-one
CAS 899397-99-0C25H28N2O2
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C24H26N2O3, CAS 1164522-61-5
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6-hydroxy-7-methyl-2H-chromen-2-one
CAS 1164522-61-5C24H26N2O3
4-{[4-((2E)-3-Phenylprop-2-enyl)piperazinyl]methyl}-6-ethylchromen-2-one chemical structure, C25H28N2O2, CAS 1178090-44-2
4-{[4-((2E)-3-Phenylprop-2-enyl)piperazinyl]methyl}-6-ethylchromen-2-one
CAS 1178090-44-2C25H28N2O2
6-Chloro-7-methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one chemical structure, C24H25ClN2O2, CAS 899405-00-6
6-Chloro-7-methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one
CAS 899405-00-6C24H25ClN2O2
6-Methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one chemical structure, C24H26N2O2, CAS 900297-76-9
6-Methyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one
CAS 900297-76-9C24H26N2O2
(E)-6-Chloro-4-((4-cinnamylpiperazin-1-yl)methyl)-2H-chromen-2-one chemical structure, C23H23ClN2O2, CAS 900281-49-4
(E)-6-Chloro-4-((4-cinnamylpiperazin-1-yl)methyl)-2H-chromen-2-one
CAS 900281-49-4C23H23ClN2O2
6,7-Dimethyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one chemical structure, C25H28N2O2, CAS 896804-39-0
6,7-Dimethyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one
CAS 896804-39-0C25H28N2O2
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-5,7-dimethyl-2H-chromen-2-one chemical structure, C25H28N2O2, CAS 1164526-67-3
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-5,7-dimethyl-2H-chromen-2-one
CAS 1164526-67-3C25H28N2O2
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6-hydroxy-2H-chromen-2-one chemical structure, C23H24N2O3, CAS 1164493-53-1
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-6-hydroxy-2H-chromen-2-one
CAS 1164493-53-1C23H24N2O3
(E)-6-Chloro-4-((4-cinnamylpiperazin-1-yl)methyl)-7-hydroxy-2H-chromen-2-one chemical structure, C23H23ClN2O3, CAS 896837-65-3
(E)-6-Chloro-4-((4-cinnamylpiperazin-1-yl)methyl)-7-hydroxy-2H-chromen-2-one
CAS 896837-65-3C23H23ClN2O3
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-7-hydroxy-8-methyl-2H-chromen-2-one chemical structure, C24H26N2O3, CAS 900278-12-8
(E)-4-((4-Cinnamylpiperazin-1-yl)methyl)-7-hydroxy-8-methyl-2H-chromen-2-one
CAS 900278-12-8C24H26N2O3
6-Ethyl-7-hydroxy-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one chemical structure, C25H28N2O3, CAS 896074-47-8
6-Ethyl-7-hydroxy-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one
CAS 896074-47-8C25H28N2O3
6-Ethyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one dihydrochloride chemical structure, C25H30Cl2N2O2, CAS 1177573-26-0
6-Ethyl-4-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)-2H-chromen-2-one dihydrochloride
CAS 1177573-26-0C25H30Cl2N2O2