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Murcko scaffold

Ring system with 4 rings and 27 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(Nc1ccc(Oc2ccnc3ccccc23)cc1)Oc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(Oc2ccnc3ccccc23)cc1)Oc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Phenyl N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}carbamate chemical structure, C24H20N2O5, CAS 347151-53-5
Phenyl N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}carbamate
CAS 347151-53-5C24H20N2O5
Phenyl N-(2-chloro-4-(7-methoxy-6-methoxycarbonyl-4-quinolyl)oxyphenyl)carbamate chemical structure, C25H19ClN2O6, CAS 417723-09-2
Phenyl N-(2-chloro-4-(7-methoxy-6-methoxycarbonyl-4-quinolyl)oxyphenyl)carbamate
CAS 417723-09-2C25H19ClN2O6
(4-((6-(Aminocarbonyl)-7-methoxy-4-quinolinyl)oxy)-2-chlorophenyl)carbamic acid phenyl ester chemical structure, C24H18ClN3O5, CAS 417722-95-3
(4-((6-(Aminocarbonyl)-7-methoxy-4-quinolinyl)oxy)-2-chlorophenyl)carbamic acid phenyl ester
CAS 417722-95-3C24H18ClN3O5
Phenyl N-[4-[6-carbamoyl-7-(2-methoxyethoxy)quinolin-4-yl]oxyphenyl]carbamate chemical structure, C26H23N3O6, CAS 417722-87-3
Phenyl N-[4-[6-carbamoyl-7-(2-methoxyethoxy)quinolin-4-yl]oxyphenyl]carbamate
CAS 417722-87-3C26H23N3O6
Phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2,3-dimethylphenyl)carbamate chemical structure, C26H23N3O5, CAS 417723-78-5
Phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl)oxy-2,3-dimethylphenyl)carbamate
CAS 417723-78-5C26H23N3O5
4-(6,7-Dimethoxyquinolin-4-yloxy)-2-fluorophenylcarbamic acid phenyl ester chemical structure, C24H19FN2O5, CAS 417724-33-5
4-(6,7-Dimethoxyquinolin-4-yloxy)-2-fluorophenylcarbamic acid phenyl ester
CAS 417724-33-5C24H19FN2O5
[4-(6-Carbamoyl-7-methoxy-4-quinolyl)oxy-2-methylphenyl]carbamic acid phenyl ester chemical structure, C25H21N3O5, CAS 417723-73-0
[4-(6-Carbamoyl-7-methoxy-4-quinolyl)oxy-2-methylphenyl]carbamic acid phenyl ester
CAS 417723-73-0C25H21N3O5
Phenyl N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]carbamate chemical structure, C25H21N3O5, CAS 417723-70-7
Phenyl N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]carbamate
CAS 417723-70-7C25H21N3O5
Phenyl N-[4-(6-carbamoyl-7-methoxyquinolin-4-yl)oxy-3-methylphenyl]carbamate chemical structure, C25H21N3O5, CAS 417722-53-3
Phenyl N-[4-(6-carbamoyl-7-methoxyquinolin-4-yl)oxy-3-methylphenyl]carbamate
CAS 417722-53-3C25H21N3O5