CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
9
With full pages
2
Scaffold SMILES

O=C(N=C1c2ccccc2CN1c1ccccc1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(N=C1c2ccccc2CN1c1ccccc1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Ethyl 4-{1-[(2-chloropyridine-3-carbonyl)imino]-2,3-dihydro-1H-isoindol-2-yl}benzoate chemical structure, C23H18ClN3O3, CAS 325821-92-9
Ethyl 4-{1-[(2-chloropyridine-3-carbonyl)imino]-2,3-dihydro-1H-isoindol-2-yl}benzoate
CAS 325821-92-9C23H18ClN3O3
6-Chloro-N-[2-(3-methylphenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C21H16ClN3O, CAS 1164483-07-1
6-Chloro-N-[2-(3-methylphenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 1164483-07-1C21H16ClN3O
6-Chloro-N-[2-(3,5-dichlorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C20H12Cl3N3O, CAS 748786-42-7
6-Chloro-N-[2-(3,5-dichlorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 748786-42-7C20H12Cl3N3O
2-Chloro-N-[2-(4-cyanophenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C21H13ClN4O, CAS 1164482-61-4
2-Chloro-N-[2-(4-cyanophenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 1164482-61-4C21H13ClN4O
2-Chloro-N-[2-(3-chloro-4-fluorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C20H12Cl2FN3O, CAS 1164531-68-3
2-Chloro-N-[2-(3-chloro-4-fluorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 1164531-68-3C20H12Cl2FN3O
2-Chloro-N-[2-(4-methoxyphenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C21H16ClN3O2, CAS 729581-86-6
2-Chloro-N-[2-(4-methoxyphenyl)-2,3-dihydro-1H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 729581-86-6C21H16ClN3O2
6-Chloro-N-[2-(4-fluorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C20H13ClFN3O, CAS 1164468-07-8
6-Chloro-N-[2-(4-fluorophenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 1164468-07-8C20H13ClFN3O
2-Chloro-N-[2-[3-(diethylsulfamoyl)phenyl]-3H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C24H23ClN4O3S, CAS 729581-82-2
2-Chloro-N-[2-[3-(diethylsulfamoyl)phenyl]-3H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 729581-82-2C24H23ClN4O3S
6-Chloro-N-[2-(4-propan-2-ylphenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide chemical structure, C23H20ClN3O, CAS 730965-71-6
6-Chloro-N-[2-(4-propan-2-ylphenyl)-3H-isoindol-1-ylidene]pyridine-3-carboxamide
CAS 730965-71-6C23H20ClN3O