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Murcko scaffold

N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide scaffold

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
16
With full pages
2
Scaffold SMILES

O=C(Nc1c(-c2ccccc2)nc2ncccn12)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide page
Murcko scaffold O=C(Nc1c(-c2ccccc2)nc2ncccn12)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide chemical structure, C19H14N4O, CAS 302817-95-4
N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide
CAS 302817-95-4C19H14N4O
4-Chloro-N-{2-phenylimidazo[1,2-a]pyrimidin-3-yl}benzamide chemical structure, C19H13ClN4O, CAS 314045-86-8
4-Chloro-N-{2-phenylimidazo[1,2-a]pyrimidin-3-yl}benzamide
CAS 314045-86-8C19H13ClN4O
N-[2-(4-Fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]-4-methylbenzamide chemical structure, C20H15FN4O, CAS 780794-23-2
N-[2-(4-Fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]-4-methylbenzamide
CAS 780794-23-2C20H15FN4O
N-[2-(4-Methylphenyl)imidazo[1,2-a]pyrimidin-3-yl]-3-(trifluoromethyl)benzamide chemical structure, C21H15F3N4O, CAS 863587-90-0
N-[2-(4-Methylphenyl)imidazo[1,2-a]pyrimidin-3-yl]-3-(trifluoromethyl)benzamide
CAS 863587-90-0C21H15F3N4O
N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide chemical structure, C19H13ClN4O, CAS 866248-12-6
N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide
CAS 866248-12-6C19H13ClN4O
4-Chloro-N-[2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide chemical structure, C19H12ClFN4O, CAS 866248-13-7
4-Chloro-N-[2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide
CAS 866248-13-7C19H12ClFN4O
4-Bromo-N-[2-(4-chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide chemical structure, C19H12BrClN4O, CAS 866248-16-0
4-Bromo-N-[2-(4-chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide
CAS 866248-16-0C19H12BrClN4O
4-Fluoro-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide chemical structure, C19H13FN4O, CAS 866248-19-3
4-Fluoro-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide
CAS 866248-19-3C19H13FN4O
4-Methyl-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide chemical structure, C20H16N4O, CAS 866248-20-6
4-Methyl-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide
CAS 866248-20-6C20H16N4O
4-Methoxy-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide chemical structure, C20H16N4O2, CAS 866248-21-7
4-Methoxy-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamide
CAS 866248-21-7C20H16N4O2
N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]-4-methylbenzamide chemical structure, C20H15ClN4O, CAS 866248-27-3
N-[2-(4-Chlorophenyl)imidazo[1,2-a]pyrimidin-3-yl]-4-methylbenzamide
CAS 866248-27-3C20H15ClN4O
N-{2-Phenylimidazo[1,2-a]pyrimidin-3-yl}-3-(trifluoromethyl)benzamide chemical structure, C20H13F3N4O, CAS 863587-83-1
N-{2-Phenylimidazo[1,2-a]pyrimidin-3-yl}-3-(trifluoromethyl)benzamide
CAS 863587-83-1C20H13F3N4O
N-(2-(p-Tolyl)imidazo[1,2-a]pyrimidin-3-yl)-4-(trifluoromethyl)benzamide chemical structure, C21H15F3N4O, CAS 863587-92-2
N-(2-(p-Tolyl)imidazo[1,2-a]pyrimidin-3-yl)-4-(trifluoromethyl)benzamide
CAS 863587-92-2C21H15F3N4O
N-[2-(4-Methylphenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide chemical structure, C20H16N4O, CAS 865284-98-6
N-[2-(4-Methylphenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide
CAS 865284-98-6C20H16N4O
N-[2-(4-Fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide chemical structure, C19H13FN4O, CAS 865285-03-6
N-[2-(4-Fluorophenyl)imidazo[1,2-a]pyrimidin-3-yl]benzamide
CAS 865285-03-6C19H13FN4O
N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)-4-(trifluoromethyl)benzamide chemical structure, C20H13F3N4O, CAS 863587-85-3
N-(2-Phenylimidazo[1,2-a]pyrimidin-3-yl)-4-(trifluoromethyl)benzamide
CAS 863587-85-3C20H13F3N4O