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Murcko scaffold

4-[[3-(Piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one scaffold

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
15
With full pages
3
Scaffold SMILES

O=C(c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-[[3-(Piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one page
Murcko scaffold O=C(c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

4-((4-Fluoro-3-(piperazine-1-carbonyl)phenyl)methyl)-1,2-dihydrophthalazin-1-one chemical structure, C20H19FN4O2, CAS 2191454-50-7
4-((4-Fluoro-3-(piperazine-1-carbonyl)phenyl)methyl)-1,2-dihydrophthalazin-1-one
CAS 2191454-50-7C20H19FN4O2
tert-Butyl 4-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}piperazine-1-carboxylate chemical structure, C25H27FN4O4, CAS 763114-04-1
tert-Butyl 4-{2-fluoro-5-[(4-oxo-3,4-dihydrophthalazin-1-yl)methyl]benzoyl}piperazine-1-carboxylate
CAS 763114-04-1C25H27FN4O4
4-[[3-(Piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one chemical structure, C20H20N4O2, CAS 763111-46-2
4-[[3-(Piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
CAS 763111-46-2C20H20N4O2
4-(3-(4-Acetylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one chemical structure, C22H21FN4O3, CAS 848136-41-4
4-(3-(4-Acetylpiperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
CAS 848136-41-4C22H21FN4O3
4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one 2,2,2-trifluoroacetate chemical structure, C22H20F4N4O4, CAS 1379676-55-7
4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one 2,2,2-trifluoroacetate
CAS 1379676-55-7C22H20F4N4O4
Olaparib impurity 15 chemical structure, C24H25FN4O3, CAS 2250243-17-3
Olaparib impurity 15
CAS 2250243-17-3C24H25FN4O3
4-(4-Fluoro-3-(4-(4-hydroxybutanoyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one chemical structure, C24H25FN4O4, CAS 2514757-44-7
4-(4-Fluoro-3-(4-(4-hydroxybutanoyl)piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
CAS 2514757-44-7C24H25FN4O4
12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanoic acid chemical structure, C32H39FN4O5, CAS 2631575-50-1
12-(4-(2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanoic acid
CAS 2631575-50-1C32H39FN4O5
4-{[4-Fluoro-3-(4-nitrosopiperazine-1-carbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one chemical structure, C20H18FN5O3, CAS 2742659-74-9
4-{[4-Fluoro-3-(4-nitrosopiperazine-1-carbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one
CAS 2742659-74-9C20H18FN5O3
6-Ethynyl-4-[[4-fluoro-3-(4-prop-2-enoylpiperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one chemical structure, C25H21FN4O3, CAS 2991637-98-8
6-Ethynyl-4-[[4-fluoro-3-(4-prop-2-enoylpiperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
CAS 2991637-98-8C25H21FN4O3
1-Piperazinebutanoic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|A-oxo- chemical structure, C24H23FN4O5, CAS 2380303-90-0
1-Piperazinebutanoic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|A-oxo-
CAS 2380303-90-0C24H23FN4O5
1-Piperazineoctanoic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|C-oxo- chemical structure, C28H31FN4O5, CAS 2631575-47-6
1-Piperazineoctanoic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|C-oxo-
CAS 2631575-47-6C28H31FN4O5
4-[5-[(3,4-Dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|A-oxo-1-piperazinehexanoic acid chemical structure, C26H27FN4O5, CAS 2631575-46-5
4-[5-[(3,4-Dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-|A-oxo-1-piperazinehexanoic acid
CAS 2631575-46-5C26H27FN4O5
[7-(Hydroxyamino)-7-oxoheptyl] 4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazine-1-carbodithioate chemical structure, C28H32FN5O4S2, CAS 2928537-98-6
[7-(Hydroxyamino)-7-oxoheptyl] 4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazine-1-carbodithioate
CAS 2928537-98-6C28H32FN5O4S2
Orb3236173 chemical structure, C35H46FN5O5, CAS 2925181-85-5
Orb3236173
CAS 2925181-85-5C35H46FN5O5