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Murcko scaffold

Ring system with 4 rings and 27 atoms

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
26
With full pages
6
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2cccc(NCc3ccco3)c2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCN(c2cccc(NCc3ccco3)c2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(3-methylphenyl)methanone chemical structure, C23H24N4O4, CAS 347313-56-8
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(3-methylphenyl)methanone
CAS 347313-56-8C23H24N4O4
(2-Chloro-4,5-difluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H19ClF2N4O4, CAS 347313-09-1
(2-Chloro-4,5-difluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 347313-09-1C22H19ClF2N4O4
(3-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21ClN4O4, CAS 347313-31-9
(3-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 347313-31-9C22H21ClN4O4
(4-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21BrN4O4, CAS 347311-65-3
(4-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 347311-65-3C22H21BrN4O4
(2-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21FN4O4, CAS 381703-18-0
(2-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 381703-18-0C22H21FN4O4
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-phenylmethanone chemical structure, C22H22N4O4, CAS 430455-26-8
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-phenylmethanone
CAS 430455-26-8C22H22N4O4
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-methylphenyl)methanone chemical structure, C23H24N4O4, CAS 439946-42-6
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-methylphenyl)methanone
CAS 439946-42-6C23H24N4O4
(4-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21FN4O4, CAS 439946-41-5
(4-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 439946-41-5C22H21FN4O4
(2-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21BrN4O4, CAS 430450-57-0
(2-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 430450-57-0C22H21BrN4O4
(4-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21ClN4O4, CAS 430450-89-8
(4-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 430450-89-8C22H21ClN4O4
(2-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21ClN4O4, CAS 430450-92-3
(2-Chlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 430450-92-3C22H21ClN4O4
(3-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21BrN4O4, CAS 432499-93-9
(3-Bromophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 432499-93-9C22H21BrN4O4
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(3-methoxyphenyl)methanone chemical structure, C23H24N4O5, CAS 432513-06-9
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(3-methoxyphenyl)methanone
CAS 432513-06-9C23H24N4O5
(3-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H21FN4O4, CAS 432515-80-5
(3-Fluorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 432515-80-5C22H21FN4O4
(4-tert-Butylphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C26H30N4O4, CAS 432519-92-1
(4-tert-Butylphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 432519-92-1C26H30N4O4
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(2-methylphenyl)methanone chemical structure, C23H24N4O4, CAS 432527-29-2
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(2-methylphenyl)methanone
CAS 432527-29-2C23H24N4O4
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-methoxyphenyl)methanone chemical structure, C23H24N4O5, CAS 433238-37-0
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-methoxyphenyl)methanone
CAS 433238-37-0C23H24N4O5
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-propan-2-ylphenyl)methanone chemical structure, C25H28N4O4, CAS 509113-34-2
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-propan-2-ylphenyl)methanone
CAS 509113-34-2C25H28N4O4
(3,4-Dichlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C22H20Cl2N4O4, CAS 524034-63-7
(3,4-Dichlorophenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 524034-63-7C22H20Cl2N4O4
(3-Ethoxyphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C24H26N4O5, CAS 591736-90-2
(3-Ethoxyphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 591736-90-2C24H26N4O5
(4-{3-[(Furan-2-ylmethyl)amino]-4-nitrophenyl}piperazin-1-yl)[3-(propan-2-yloxy)phenyl]methanone chemical structure, C25H28N4O5, CAS 593237-77-5
(4-{3-[(Furan-2-ylmethyl)amino]-4-nitrophenyl}piperazin-1-yl)[3-(propan-2-yloxy)phenyl]methanone
CAS 593237-77-5C25H28N4O5
(4-Ethylphenyl)(4-{3-[(furan-2-ylmethyl)amino]-4-nitrophenyl}piperazin-1-yl)methanone chemical structure, C24H26N4O4, CAS 593237-86-6
(4-Ethylphenyl)(4-{3-[(furan-2-ylmethyl)amino]-4-nitrophenyl}piperazin-1-yl)methanone
CAS 593237-86-6C24H26N4O4
(3,4-Dimethoxyphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone chemical structure, C24H26N4O6, CAS 714279-35-3
(3,4-Dimethoxyphenyl)-[4-[3-(furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]methanone
CAS 714279-35-3C24H26N4O6
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-propan-2-yloxyphenyl)methanone chemical structure, C25H28N4O5, CAS 717829-47-5
[4-[3-(Furan-2-ylmethylamino)-4-nitrophenyl]piperazin-1-yl]-(4-propan-2-yloxyphenyl)methanone
CAS 717829-47-5C25H28N4O5