CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
10
With full pages
1
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2cccc(NCC3CCCO3)c2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCN(c2cccc(NCC3CCCO3)c2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

(4-Methylphenyl)(4-{4-nitro-3-[(tetrahydrofuran-2-ylmethyl)amino]phenyl}piperazin-1-yl)methanone chemical structure, C23H28N4O4, CAS 524034-96-6
(4-Methylphenyl)(4-{4-nitro-3-[(tetrahydrofuran-2-ylmethyl)amino]phenyl}piperazin-1-yl)methanone
CAS 524034-96-6C23H28N4O4
(3,4-Dichlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H24Cl2N4O4, CAS 524034-87-5
(3,4-Dichlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 524034-87-5C22H24Cl2N4O4
(4-Chlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H25ClN4O4, CAS 524034-65-9
(4-Chlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 524034-65-9C22H25ClN4O4
(2-Fluorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H25FN4O4, CAS 591726-77-1
(2-Fluorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 591726-77-1C22H25FN4O4
(4-tert-Butylphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C26H34N4O4, CAS 591736-98-0
(4-tert-Butylphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 591736-98-0C26H34N4O4
(3-Chlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H25ClN4O4, CAS 642430-28-2
(3-Chlorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 642430-28-2C22H25ClN4O4
(4-Fluorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H25FN4O4, CAS 642430-24-8
(4-Fluorophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 642430-24-8C22H25FN4O4
(4-Methoxyphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C23H28N4O5, CAS 593238-03-0
(4-Methoxyphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 593238-03-0C23H28N4O5
(3-Bromophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C22H25BrN4O4, CAS 578759-17-8
(3-Bromophenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 578759-17-8C22H25BrN4O4
(2-Methylphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone chemical structure, C23H28N4O4, CAS 708229-39-4
(2-Methylphenyl)-[4-[4-nitro-3-(oxolan-2-ylmethylamino)phenyl]piperazin-1-yl]methanone
CAS 708229-39-4C23H28N4O4