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Murcko scaffold

Ring system with 3 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
10
With full pages
2
Scaffold SMILES

O=C1CN=C(c2ccccc2)c2cn[nH]c2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CN=C(c2ccccc2)c2cn[nH]c2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Zolazepam chemical structure, C15H15FN4O, CAS 31352-82-6
Zolazepam
CAS 31352-82-6C15H15FN4O
Pyrazolo(3,4-e)(1,4)diazepin-7(1H)-one, 4-(2-fluorophenyl)-6,8-dihydro-1,3,8-trimethyl-, mixt. with 2-(ethylamino)-2-(2-thienyl)cyclohexanone chemical structure, C27H33N5O3S, CAS 60893-97-2
Pyrazolo(3,4-e)(1,4)diazepin-7(1H)-one, 4-(2-fluorophenyl)-6,8-dihydro-1,3,8-trimethyl-, mixt. with 2-(ethylamino)-2-(2-thienyl)cyclohexanone
CAS 60893-97-2C27H33N5O3S
Zoletil chemical structure, C27H34Cl2FN5O2S, CAS 75418-09-6
Zoletil
CAS 75418-09-6C27H34Cl2FN5O2S
Zolazepam hydrochloride chemical structure, C15H16ClFN4O, CAS 33754-49-3
Zolazepam hydrochloride
CAS 33754-49-3C15H16ClFN4O
Tilazol chemical structure, C27H33ClFN5O2S, CAS 37291-85-3
Tilazol
CAS 37291-85-3C27H33ClFN5O2S
4-(2-Chlorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo[3,4-e][1,4]diazepin-7(1H)-one chemical structure, C15H15ClN4O, CAS 111424-65-8
4-(2-Chlorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo[3,4-e][1,4]diazepin-7(1H)-one
CAS 111424-65-8C15H15ClN4O
Zolazepam-d3 chemical structure, C15H15FN4O, CAS 1286480-83-8
Zolazepam-d3
CAS 1286480-83-8C15H15FN4O
1,8-Didemethyl zolazepam chemical structure, C13H11FN4O, CAS 55199-54-7
1,8-Didemethyl zolazepam
CAS 55199-54-7C13H11FN4O
8-Demethyl-6-hydroxy Zolazepam chemical structure, C14H13FN4O2, CAS 55199-56-9
8-Demethyl-6-hydroxy Zolazepam
CAS 55199-56-9C14H13FN4O2
8-Demethyl zolazepam chemical structure, C14H13FN4O, CAS 31271-94-0
8-Demethyl zolazepam
CAS 31271-94-0C14H13FN4O