CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
16
With full pages
1
Scaffold SMILES

O=C1CN=C(c2ccccc2)c2c[nH]cc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CN=C(c2ccccc2)c2c[nH]cc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Premazepam chemical structure, C15H15N3O, CAS 57435-86-6
Premazepam
CAS 57435-86-6C15H15N3O
8-Ethyl-3,7-dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-E)-1,4-diazepin-2(1H)-one chemical structure, C17H19N3O, CAS 57435-88-8
8-Ethyl-3,7-dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-E)-1,4-diazepin-2(1H)-one
CAS 57435-88-8C17H19N3O
5-(2-Fluorophenyl)-6-methyl-3,7-dihydropyrrolo[3,4-e][1,4]diazepin-2(1H)-one chemical structure, C14H12FN3O, CAS 57435-90-2
5-(2-Fluorophenyl)-6-methyl-3,7-dihydropyrrolo[3,4-e][1,4]diazepin-2(1H)-one
CAS 57435-90-2C14H12FN3O
3,7-Dihydro-6-methyl-5-phenylpyrrolo(3,4-E)-1,4-diazepin-2(1H)-one chemical structure, C14H13N3O, CAS 57435-84-4
3,7-Dihydro-6-methyl-5-phenylpyrrolo(3,4-E)-1,4-diazepin-2(1H)-one
CAS 57435-84-4C14H13N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-(2-chlorophenyl)-6-methyl- chemical structure, C14H12ClN3O, CAS 57435-89-9
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-(2-chlorophenyl)-6-methyl-
CAS 57435-89-9C14H12ClN3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-(p-methoxyphenyl)-6-methyl- chemical structure, C15H15N3O2, CAS 57435-91-3
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-(p-methoxyphenyl)-6-methyl-
CAS 57435-91-3C15H15N3O2
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-ethyl-6-methyl-5-phenyl- chemical structure, C16H17N3O, CAS 57435-92-4
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-ethyl-6-methyl-5-phenyl-
CAS 57435-92-4C16H17N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6-methyl-5-phenyl-7-propyl- chemical structure, C17H19N3O, CAS 57435-93-5
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6-methyl-5-phenyl-7-propyl-
CAS 57435-93-5C17H19N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-butyl-6-methyl-5-phenyl- chemical structure, C18H21N3O, CAS 57435-94-6
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-butyl-6-methyl-5-phenyl-
CAS 57435-94-6C18H21N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-isobutyl-6-methyl-5-phenyl- chemical structure, C18H21N3O, CAS 57435-95-7
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-7-isobutyl-6-methyl-5-phenyl-
CAS 57435-95-7C18H21N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-phenyl-1,6,7-trimethyl- chemical structure, C16H17N3O, CAS 57436-05-2
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-5-phenyl-1,6,7-trimethyl-
CAS 57436-05-2C16H17N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-1-ethyl-5-phenyl- chemical structure, C17H19N3O, CAS 57436-06-3
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-1-ethyl-5-phenyl-
CAS 57436-06-3C17H19N3O
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-8-ethyl-6-methyl-5-phenyl- chemical structure, C16H17N3O, CAS 57517-34-7
Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one, 3,7-dihydro-8-ethyl-6-methyl-5-phenyl-
CAS 57517-34-7C16H17N3O
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-8-bromo-6,7-dimethyl-5-phenyl- chemical structure, C15H14BrN3O, CAS 84829-73-2
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-8-bromo-6,7-dimethyl-5-phenyl-
CAS 84829-73-2C15H14BrN3O
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-8-chloro-6,7-dimethyl-5-phenyl- chemical structure, C15H14ClN3O, CAS 84829-74-3
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-8-chloro-6,7-dimethyl-5-phenyl-
CAS 84829-74-3C15H14ClN3O
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-8-nitro-5-phenyl- chemical structure, C15H14N4O3, CAS 84829-75-4
Pyrrolo(3,4-e)-1,4-diazepin-2(1H)-one, 3,7-dihydro-6,7-dimethyl-8-nitro-5-phenyl-
CAS 84829-75-4C15H14N4O3