CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
12
With full pages
7
Scaffold SMILES

O=c1[nH]cc(S(=O)(=O)NCc2ccccc2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(S(=O)(=O)NCc2ccccc2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-Hydroxy-N-(4-methoxybenzyl)-4-methyl-6-oxo-1,6-dihydropyrimidine-5-sulfonamide chemical structure, C13H15N3O5S, CAS 346631-38-7
2-Hydroxy-N-(4-methoxybenzyl)-4-methyl-6-oxo-1,6-dihydropyrimidine-5-sulfonamide
CAS 346631-38-7C13H15N3O5S
N-Benzyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C13H15N3O4S, CAS 874806-19-6
N-Benzyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-19-6C13H15N3O4S
1,3-Dimethyl-N-[(4-methylphenyl)methyl]-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 874806-24-3
1,3-Dimethyl-N-[(4-methylphenyl)methyl]-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-24-3C14H17N3O4S
N-(4-Chlorobenzyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C13H14ClN3O4S, CAS 893357-01-2
N-(4-Chlorobenzyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 893357-01-2C13H14ClN3O4S
N-Benzyl-N-ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C15H19N3O4S, CAS 874806-36-7
N-Benzyl-N-ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-36-7C15H19N3O4S
N-[(4-Methoxyphenyl)methyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C14H17N3O5S, CAS 874806-43-6
N-[(4-Methoxyphenyl)methyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 874806-43-6C14H17N3O5S
N-Benzyl-N-ethyl-1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C16H21N3O4S, CAS 893339-00-9
N-Benzyl-N-ethyl-1,3,6-trimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 893339-00-9C16H21N3O4S
6-Amino-N-benzyl-N-ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C15H20N4O4S, CAS 893377-53-2
6-Amino-N-benzyl-N-ethyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 893377-53-2C15H20N4O4S
N-[(4-Methylphenyl)methyl]-2,4-dioxo-1H-pyrimidine-5-sulfonamide chemical structure, C12H13N3O4S, CAS 897622-54-7
N-[(4-Methylphenyl)methyl]-2,4-dioxo-1H-pyrimidine-5-sulfonamide
CAS 897622-54-7C12H13N3O4S
N-[(4-Fluorophenyl)methyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide chemical structure, C13H14FN3O4S, CAS 893358-05-9
N-[(4-Fluorophenyl)methyl]-1,3-dimethyl-2,4-dioxopyrimidine-5-sulfonamide
CAS 893358-05-9C13H14FN3O4S
6-Amino-1,3-dimethyl-2,4-dioxo-N-(1-phenylethyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C14H18N4O4S, CAS 893379-13-0
6-Amino-1,3-dimethyl-2,4-dioxo-N-(1-phenylethyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 893379-13-0C14H18N4O4S
1,3-Dimethyl-2,4-dioxo-N-(1-phenylethyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide chemical structure, C14H17N3O4S, CAS 874806-60-7
1,3-Dimethyl-2,4-dioxo-N-(1-phenylethyl)-1,2,3,4-tetrahydropyrimidine-5-sulfonamide
CAS 874806-60-7C14H17N3O4S