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Murcko scaffold

Ring system with 2 rings and 16 atoms

2,317 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
2,317
With full pages
389
Scaffold SMILES

O=C(C=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 2,317 chemicals

2-(3,4-Dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile chemical structure, C16H11NO5, CAS 875283-46-8
2-(3,4-Dihydroxybenzoyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
CAS 875283-46-8C16H11NO5
3-(2,4-Dihydroxyphenyl)-1-phenyl-2-propen-1-one chemical structure, C15H12O3, CAS 92496-59-8
3-(2,4-Dihydroxyphenyl)-1-phenyl-2-propen-1-one
CAS 92496-59-8C15H12O3
2'-4-Dihydroxychalcone chemical structure, C15H12O3
2'-4-Dihydroxychalcone
C15H12O3
3-Hydroxy-1,3-diphenyl-propenone chemical structure, C15H12O2, CAS 1704-15-0
3-Hydroxy-1,3-diphenyl-propenone
CAS 1704-15-0C15H12O2
N-(4-Hydroxy-3-(1-oxo-3-phenyl-2-propen-1-yl)phenyl)acetamide chemical structure, C17H15NO3, CAS 24449-58-9
N-(4-Hydroxy-3-(1-oxo-3-phenyl-2-propen-1-yl)phenyl)acetamide
CAS 24449-58-9C17H15NO3
3-Nitrochalcone chemical structure, C15H11NO3, CAS 614-48-2
3-Nitrochalcone
CAS 614-48-2C15H11NO3
1-(5-Chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one chemical structure, C15H10Cl2O2, CAS 36768-48-6
1-(5-Chloro-2-hydroxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one
CAS 36768-48-6C15H10Cl2O2
alpha-Methylchalcone chemical structure, C16H14O, CAS 4258-37-1
alpha-Methylchalcone
CAS 4258-37-1C16H14O
1,3-Bis(4-(dimethylamino)phenyl)-2-propen-1-one chemical structure, C19H22N2O, CAS 1161-22-4
1,3-Bis(4-(dimethylamino)phenyl)-2-propen-1-one
CAS 1161-22-4C19H22N2O
2',4,4',6'-Tetrahydroxy-3-methoxychalcone chemical structure, C16H14O6, CAS 52218-19-6
2',4,4',6'-Tetrahydroxy-3-methoxychalcone
CAS 52218-19-6C16H14O6
1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one chemical structure, C21H22O4, CAS 54647-08-4
1-[2-Hydroxy-4-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
CAS 54647-08-4C21H22O4
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one chemical structure, C17H16O5, CAS 20621-49-2
1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
CAS 20621-49-2C17H16O5
3-Mercapto-1,3-diphenylprop-2-en-1-one chemical structure, C15H12OS, CAS 2276-40-6
3-Mercapto-1,3-diphenylprop-2-en-1-one
CAS 2276-40-6C15H12OS
3-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-2-propen-1-one chemical structure, C16H14O3, CAS 89406-16-6
3-(4-Hydroxy-3-methoxyphenyl)-1-phenyl-2-propen-1-one
CAS 89406-16-6C16H14O3
2',4'-Dihydroxy-6'-methoxychalcone chemical structure, C16H14O4, CAS 18956-16-6
2',4'-Dihydroxy-6'-methoxychalcone
CAS 18956-16-6C16H14O4
1-(2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl)-3-(4-hydroxyphenyl)-2-propen-1-one chemical structure, C21H22O5, CAS 569-83-5
1-(2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
CAS 569-83-5C21H22O5
2',4',4-Trihydroxy-6'-methoxychalcone chemical structure, C16H14O5, CAS 56121-43-8
2',4',4-Trihydroxy-6'-methoxychalcone
CAS 56121-43-8C16H14O5
3-(4-Chlorophenyl)-1-(4-hydroxyphenyl)-2-propen-1-one chemical structure, C15H11ClO2, CAS 19152-38-6
3-(4-Chlorophenyl)-1-(4-hydroxyphenyl)-2-propen-1-one
CAS 19152-38-6C15H11ClO2
2'-Hydroxy-4,3',4',6'-tetramethoxychalcone chemical structure, C19H20O6, CAS 91856-17-6
2'-Hydroxy-4,3',4',6'-tetramethoxychalcone
CAS 91856-17-6C19H20O6
3-(Diethylamino)-1,3-diphenylprop-2-en-1-one chemical structure, C19H21NO, CAS 5443-62-9
3-(Diethylamino)-1,3-diphenylprop-2-en-1-one
CAS 5443-62-9C19H21NO
1,3-Bis(4-chlorophenyl)but-2-en-1-one chemical structure, C16H12Cl2O
1,3-Bis(4-chlorophenyl)but-2-en-1-one
C16H12Cl2O
2-Propen-1-one, 3-(3-methoxyphenyl)-1-phenyl- chemical structure, C16H14O2, CAS 22966-05-8
2-Propen-1-one, 3-(3-methoxyphenyl)-1-phenyl-
CAS 22966-05-8C16H14O2
Carbanilic acid, p-[p-(dimethylamino)cinnamoyl]-, ethyl ester chemical structure, C20H22N2O3, CAS 5394-70-7
Carbanilic acid, p-[p-(dimethylamino)cinnamoyl]-, ethyl ester
CAS 5394-70-7C20H22N2O3
2-Buten-1-one,1,3-bis(3-nitrophenyl)- chemical structure, C16H12N2O5, CAS 7509-22-0
2-Buten-1-one,1,3-bis(3-nitrophenyl)-
CAS 7509-22-0C16H12N2O5